Results 151 to 160 of about 3,118,438 (194)
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Induction of apoptosis by fatty acid ethyl esters in HepG2 cells
Food and Chemical Toxicology, 2005Fatty acid ethyl esters (FAEEs) are esterification products of ethanol and fatty acids which have been found particularly in the organ damaged by ethanol abuse. To evaluate any effect of FAEEs on HepG2 cells, we added FAEEs to cell culture medium. Electrophoresis of DNA from HepG2 cells exposed to 18.5 microM ethyl palmitate (EP) and 10.6 microM ethyl ...
Aydin H.H. +6 more
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Fatty acid ethyl esters: Non-oxidative metabolites of ethanol
Prostaglandins, Leukotrienes and Essential Fatty Acids, 1995Fatty acid ethyl esters are esterification products of fatty acids and ethanol. These compounds have been detected in the serum and cells of individuals following ethanol ingestion. Fatty acid ethyl esters can be quantitated by gas chromatography-mass spectroscopy (GC-MS) in the serum following ethanol ingestion and have been found in concentrations up
M, Laposata +2 more
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Fatty acid ethyl esters: current facts and speculations
Prostaglandins, Leukotrienes and Essential Fatty Acids, 1999Increasing evidence indicates that fatty acid ethyl esters (FAEE) play a role in ethanol-induced organ damage and may serve as long-term markers of ethanol intake. This report summarizes the current knowledge on the toxicity of FAEE, the enzymes associated with FAEE synthesis, FAEE as fatty acid supplements, the in vivo degradation of orally ingested ...
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Fatty acid ethyl esters: nonoxidative metabolites of ethanol
Addiction Biology, 1998AbstractThe story of fatty acid ethyl (FAEE) encompasses nearly 40 years of research. For more than half of this time, the investigation was limited to documenting the presence of ethyl ester synthesis in different cells and tissues. In the last three years, increasing evidence has emerged that FAEE contribute to ethanol‐induced organ damage, with a ...
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Conversion of Alcohol to Ethyl Esters of Fatty Acids by the Lactating Goat
Nature, 1966FRESHLY secreted milk contains a lipogenic principle that will incorporate fatty acids into the ester lipids of the milk1. While investigating this principle with the aid of palmitic-l-14C acid and thin-layer chromatographic analysis of the resulting labelled lipids, we noted a prominent spot on autoradiograms between the solvent front and the position
S, Patton, R D, McCarthy
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Determination of enthalpy of formation of methyl and ethyl esters of fatty acids
Chemistry and Physics of Lipids, 2010Biofuels composed by fatty acid methyl esters are widely used as partly substituting fuels for diesel fossil fuels. Additionally, it is expected that the diesel biofuel norms will be extended to ethyl esters produced from bioethanol in the upcoming years. A precise knowledge of the standard enthalpy of formation is necessary for the calculation of some
Magín, Lapuerta +2 more
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Identification and quantitation of fatty acid ethyl esters in biological specimens
Analytical Biochemistry, 1984Fatty acid ethyl esters, recently described as enzymatic products of nonoxidative ethanol metabolism in the heart, may represent a mediator or marker of ethanol-induced organ pathology such as alcoholic cardiomyopathy. This study was designed to develop a method for the extraction, quantitation, and definitive identification of fatty acid ethyl esters ...
P M, Kinnunen, L G, Lange
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Fatty acid ethyl ester synthesis by human liver microsomes
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996Fatty acid ethyl esters are a family of non-oxidative metabolites of ethanol present in many tissues after ethanol consumption. In this report we demonstrate the existence in human liver of an acyl-CoA:ethanol acyltransferase activity which may be responsible in part for the synthesis of these compounds in vivo.
Treloar, Tony +4 more
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Fatty Acid Ethyl Ester Synthesis in the Preparation of Scotch Whiskey
Alcohol, 1999Fatty acid ethyl esters (FAEE), nonoxidative ethanol metabolites present in human organs commonly damaged by ethanol abuse, have been implicated as mediators of organ damage. FAEE are additives in various foods and beverages to provide flavor or fragrance, and therefore are common dietary lipid constituents. We hypothesized that FAEE could be generated
K A, Goss, R, Alharethi, M, Laposata
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Fatty acid ethyl esters: markers of alcohol abuse and alcoholism
Alcohol, 2004Chronic alcoholism, which is associated with hepatic, pancreatic, and myocardial diseases, is one of the major health problems in the United States with high morbidity and mortality. Many individuals who abuse alcohol chronically die even before reaching the clinical stage of the disease.
Bhupendra S, Kaphalia +4 more
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