Results 111 to 120 of about 316,994 (313)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Tradifional caffle feeding stuffs: fatty acid profile [PDF]

open access: yes, 2005
Dietary pollunsaturated fatty acids (PUFA) are perceived to be healthier ïhan sat$ated fatfy acids. Therefore, in order ïo be able to manipulate the faÍty acid prolìle ofmeat and/or miik, to respond to the consumer demands. knorvledge of the fatty acid
Pires, Jaime   +4 more
core   +1 more source

Lipid Profile and Essential Fatty Acid Concentration in Typhoid Fever Patients

open access: yesAl-Mustansiriyah Journal of Pharmaceutical Sciences, 2010
The activation of inflammatory cells, the release of their mediators, and the excessive production of free radicals may affect circulating lipids, while no evidence supports a role for peroxidation in the pathogenesis of typhoid fever disease.
Amal H.A., Eman S.S.
doaj   +1 more source

Feeding Agro-Industrial By-Products to Light Lambs: Influence on Meat Characteristics, Lipid Oxidation, and Fatty Acid Profile

open access: yes, 2020
The aim of this study was to assess the effects of replacing 44% of conventional feeds in a high-cereal concentrate (CON) with by-products (BYP concentrate; 18% corn distillers dried grains with solubles, 18% dried citrus pulp, and 8% exhausted olive ...
Carro, María Dolores   +7 more
core   +1 more source

Effect of dietary fatty acids on expression of lipogenic enzymes and fatty acid profile in tissues of bulls [PDF]

open access: yes, 2010
This study investigated the effects of dietary linolenic acid (C18:3n-3) v. linoleic acid (C18:2n-6) on fatty acid composition and protein expression of key lipogenic enzymes, acetyl-CoA carboxylase (ACC), stearoyl-CoA desaturase (SCD) and delta 6 ...
Herdmann, A.   +5 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Fatty Acid Profile of Erythrocyte Membranes in Patients with Psoriasis

open access: yesNutrients
Psoriasis is a chronic systemic disease with a multifaceted pathomechanism and immunological basis, with the presence of inflammatory skin lesions and joint ailments. Diseases accompanying psoriasis include metabolic and cardiovascular disorders. It has been suggested that inflammation is involved in the development of each of these conditions.
Mariola Marchlewicz   +9 more
openaire   +2 more sources

Effects of fatty acids on inflammatory markers studies in vitro and in vivo

open access: yes, 2008
Inflammation involves interactions amongst many different cell types as a defense mechanism of the body. Inflammation is also involved in cardiovascular disease (CVD).
Mohd Yusof, Hayati
core  

How the milk chemical composition and fatty acid profile are influenced by physiological factorsin Najdi dairy sheep [PDF]

open access: yes
Sheep milk production is a complex process that is influenced by various factors. This study aims to investigate how the litter size (single vs. twins), birth type (male vs.
Ramzi Ahmed Amran   +6 more
core   +1 more source

Laser‐Induced Graphene from Waste Almond Shells

open access: yesAdvanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova   +9 more
wiley   +1 more source

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