Results 61 to 70 of about 543,048 (306)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nutrient and fatty acid deposition in broilers fed different dietary fatty acid profiles

Poultry Science, 2002
The aim of this study was to determine the effect of different dietary fatty acid profiles on efficiency of energy, fat, nitrogen, and fatty acid deposition in broiler chickens. Sixty female broiler chickens were fed a basal diet without additional fat or with 4 other diets with different fats (tallow, olive, sunflower, and linseed oils) at 10% from 28
Crespo, N., Esteve-Garcia, Enric
openaire   +3 more sources

A Study on the Fatty Acid Profile and Conjugated Linoleic Acid (CLA) Content in Common Thai Indigenous Chickens Raised by Natural Farming in Nakhon Phanom Province

Walailak Journal of Science and Technology, 2011
This research studied the fatty acid profile and conjugated linoleic acid (CLA) content in common Thai indigenous chickens (5 months old) raised by natural farming in Nakhon Phanom province.
Tanom TATHONG, Santisook WORRAWATTANATAM
doaj   +1 more source

Bifidobacterium breve with α-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome [PDF]

, 2012
peer-reviewedThe aim of this study was to compare the impact of dietary supplementation with a Bifidobacterium breve strain together with linoleic acid & α-linolenic acid, for 7 weeks, on colonic sensitivity and fatty acid metabolism in rats.
Barrett, Eoin, Cryan, John F., Dinan, Timothy G., Fitzgerald, Gerald F, Fitzgerald, Patrick, Kiely, Barry, O'Toole, Paul W., Quigley, Eamonn M., Ross, R Paul, Shanahan, Fergus, STANTON, CATHERINE   +10 more
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Tradifional caffle feeding stuffs: fatty acid profile [PDF]

, 2005
Dietary pollunsaturated fatty acids (PUFA) are perceived to be healthier ïhan sat$ated fatfy acids. Therefore, in order ïo be able to manipulate the faÍty acid prolìle ofmeat and/or miik, to respond to the consumer demands. knorvledge of the fatty acid
Dias, L.G., Morais, Jorge Sá, Peres, António M., Pires, Jaime, Sousa, Fernando Ruivo de   +4 more
core  

Sustainability vs. Quality in gilthead seabream (Sparusaurata L.) farming: are trade-offs inevitable? [PDF]

, 2017
European aquaculture industry should be at the forefront of sustainable development, providing healthy and safe food of the highest quality to the consumer, through an environmentally sound approach.
Adams, Alasalvar, Allan, Amerio, Anastasiou, Ashie, Axel, Bagni, Benedito-Palos, Benedito-Palos, Benedito-Palos, Brundtland, Buttle, Carrera, Castro, Castro, Coppes, Damez, EFSA, EFSA, European Commission, European Commission, European Commission, Fagioli, FAO, FAO, Ferreira Pinto, Flos, Focardi, Fountoulaki, Francesco, Ganga, Ghatass, Ginés, Giuffrida, Gonçalves, Grigorakis, Grigorakis, Grigorakis, Haard, Hall, Haro, Hatlen, Hernández, Hernández, Hu, Huidobro, Huidobro, Hyldig, Iglesias, Izquierdo, Izquierdo, Jackson, Lawal, Lindemann, Martínez-Llorens, Martínez-Llorens, Matos, Matos, Matos, Matos, Matos, Meloni, Mennella, Menoyo, Mente, Mente, Mochizuki, Montero, Morales, Moretti, Nasopoulou, Naylor, Nengas, Nilsen, Nogueira, Nácher-Mestre, Nácher-Mestre, Orban, Ortuño, Picard, Piccino, Poli, Poli, Prein, Pérez, Ramalho Ribeiro, Reilly, Richard, Roncarati, Semenov, Sigholt, Silva, Silva, Sánchez-Lozano, Tejada, Terova, Trocino, Trushenski, Turchini, Urbieta, Valente, Verbeke, Vizcaíno, Volpato, Wassef, Xuan, Zhang, Álvarez, Álvarez, Álvarez-Chávez, Ólafsdóttir, Ólafsdóttir   +112 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Fatty Acid Profiles and Production in Marine Phytoplankton [PDF]

Marine Drugs, 2019
Microalgae are the primary producers of carbon in marine ecosystems, fixing carbon and subsequently generating various biomolecules such as carbohydrates, proteins and lipids. Most importantly, microalgae are the generators and main suppliers of ω3 polyunsaturated fatty acids (ω3PUFA) in the marine ecosystem, which have a fundamental importance for the
openaire   +4 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source