Results 81 to 90 of about 543,048 (306)

In vitro Antioxidant Potential of Fatty Acids Obtained by Direct Transmethylation from Fresh Cordia sebestena Flowers

open access: yesAnnals of Tropical Research, 2014
The determination of fatty acid profile of plant material is often attained via multistep procedures. Recent innovation has made it possible to obtain fatty acids from fresh matrix in a single step.
Olubunmi Atolani   +3 more
doaj   +1 more source

Fatty acids profiles of some Spanish wild vegetables [PDF]

open access: yesFood Science and Technology International, 2012
Polyunsaturated fatty acids play an important role in human nutrition, being associated with several health benefits. The analyzed vegetables, in spite of its low fat content, lower than 2%, present a high proportion of polyunsaturated fatty acids of n-3, n-6 and n-9 series, such as α-linolenic, linoleic and oleic acids, respectively.
Morales, Patricia   +5 more
openaire   +3 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Season and altitude effects on milk fatty acid profile in Sarda dairy sheep flocks [PDF]

open access: yes, 2007
Diet plays a major role in modulating the fatty acid composition of ruminant milk. It is also well known that the intake of fresh forages has a positive influence on polyunsaturated fatty acid (PUFA), particularly CLA and omega- 3, compared with diets ...
Garau, Giovanni   +4 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Eating quality of Holstein bull calves fed only grass or purely herbs matches that of concentrate-fed veal calves [PDF]

open access: yes, 2012
Organic meat production from Holstein calves born in dairy herds require that the bull calves are raised outdoor at least 6 months a year, and on large quantities of roughage in the diet.
Jensen, S.K.   +2 more
core  

Prenatal hyperandrogenism induces alterations that affect liver lipid metabolism [PDF]

open access: yes, 2016
Prenatal hyperandrogenism is hypothesized as one of the main factors contributing to26 the development of polycystic ovary syndrome (PCOS). PCOS patients have high risk27 of developing fatty liver and steatosis.
Abruzzese, Giselle Adriana   +6 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Regulatory mechanisms underlying oil palm mesocarp maturation and functional specialization in lipid and carotenoid metabolism [PDF]

open access: yes, 2012
The lipid-rich fleshy mesocarp tissue of the oil palm (Elaeis guineensis) fruit is not only the main source of edible oil for the world, but it is also the richest dietary source of provitamin A. This study examines the transcriptional basis of these two
Dussert, Stéphane   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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