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The Essential Fatty Acids

Nutrition in Clinical Practice, 1992
In animal and human tissues, there are four families of fatty acids that are derived from the precursors palmitoleic, oleic, linoleic, and linolenic acids. Of these, linoleic and linolenic acids are essential dietary elements for humans and all higher animals. The four precursor fatty acids are metabolized (through desaturation and chain elongation) to
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ESSENTIAL FATTY ACIDS AND PROSTAGLANDINS

1974
Arachidonic acid takes part in a number of complicated enzymic processes in which not only the prostaglandins but also the intermediate products of their biosynthesis have important physiological effects. The prostaglandin-synthesizing system can convert a large number of nonnatural substrates, leading to the formation of substituted prostaglandins ...
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Essential fatty acids and acne

Journal of the American Academy of Dermatology, 1986
Acne is characterized by hyperkeratosis of the follicular epithelium, leading to horny impactions that may lie dormant as open or closed comedones or may cause inflammation of the follicle. Although persons with acne have consistently been observed to have elevated levels of sebum secretion, no mechanism relating sebum secretion rates to comedogenesis ...
D T, Downing   +3 more
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Essential Fatty Acids and Osteoarthritis

Arthritis Care & Research
ObjectiveInflammation worsens joint destruction in osteoarthritis (OA) and aggravates pain. Although n‐3 fatty acids reduce inflammation, different n‐3 fatty acids have different effects on inflammation and clinical outcomes, with eicosapentaenoic acid (EPA) having the strongest effect.
David T. Felson   +9 more
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Essential fatty acids in mitochondria

Archives of Biochemistry and Biophysics, 1961
Abstract The fatty acid contents of mitochondria from chicken liver, beef heart, rat liver, catfish liver, carp liver, salmon liver, and salmon heart were determined by gas-liquid chromatography of the methyl esters. The degree of unsaturation of the fatty acids increased in the above order, and the molar amounts of essential fatty acids, arachidonic
T, RICHARDSON, A L, TAPPEL, E H, GRUGER
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Essential Fatty Acids Revisited

Archives of Pediatrics & Adolescent Medicine, 1980
Polyunsaturated fatty acids (PUFAs) are aliphatic monocarboxylic acids with two or more double bonds in any positional arrangement or geometric configuration. Those PUFAs that prevent or relieve the symptoms of dietary deficiency in humans and animals are named, therefore, the essential fatty acids (EFAs).
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Essential fatty acids and the skin

British Journal of Dermatology, 1989
The realisation that essential fatty acids are of crucial importance for the maintenance of a healthy skin coincided with their discovery. Burr and Burr (1) first described the symptoms of essential fatty acid deficiency thus: “An abnormal, scaly condition of the skin is observed between the 70th and 90th day of life.
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Essential Fatty Acids in Testes

1977
Burr & Burr (1929, 1930) originally observed that essential fatty acids are necessary for the maintenance of normal testicular function in rats. Since then the lipid composition of testes and the metabolism of testicular lipids have been studied by many investigators in an attempt to relate these to the development and function of the testis.
J G, Coniglio   +2 more
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ECZEMA AND ESSENTIAL FATTY ACIDS

Archives of Pediatrics and Adolescent Medicine, 1947
DERMATOLOGIC conditions classified perforce under the comprehensive and admittedly unsatisfactory term "eczema" constitute one of the chief problems encountered in the practice of medicine. True enough, as diagnostic methods have improved, the number of clinical conditions so designated has become fewer.
A. E. HANSEN   +4 more
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How Essential Are Fatty Acids?

JAMA, 1961
ALTHOUGH the existence of essential fatty acids (EFA) has been known for 30 years, clinical interest in these dietary substances has been slight until recently. The possible relationship of EFA to the prevention or therapy of degenerative diseases such as atherosclerosis has projected these nutrients into the first rank of medical problems and interest.
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