Results 191 to 200 of about 586,099 (248)

Rethinking diabetic retinopathy: Homeostatic mechanisms for retinal clearance

Diabetic Medicine, EarlyView.
In the healthy retina, balanced production and clearance of metabolic waste and fluid maintain retinal homeostasis and normal visual function. Diabetes disrupts this balance, increasing the accumulation of metabolic waste products, including advanced glycation end products (AGEs) and advanced lipoxidation end products (ALEs), while impairing waste and ...
Karis Little, Judith Lechner, Giulia De Rossi, Tara Cullen, Jennifer Perais, Eleni Beli, Noemi Lois, Alan W. Stitt   +7 more
wiley   +1 more source

Sex-Dependent Changes in Quality and Flavor-Related Chemical Profiles of <i>Mytilus coruscus</i> During Long-Term Frozen Storage. [PDF]

Foods
Li R, Xiu X, Xiang J, Xu K, Luo J, Wang Y, Jiang X, Liu Y, Feng T, Xue C.   +9 more
europepmc   +1 more source

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

The FEBS Journal, EarlyView.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger, Alice Wiedmann, Rayan Hassan M. Elshikhidriss, Thomas Brunner   +3 more
wiley   +1 more source

Synthesis and Activity-Based Protein Profiling Identifies Aldo-Keto Reductase 1C3 as Target Protein of Myxoglucamides. [PDF]

Angew Chem Int Ed Engl
Siemon T, Mishra VK, Zhao M, Büssow K, Popoff A, Fu C, Müller R, Jänsch L, Blankenfeldt W, Brönstrup M.   +9 more
europepmc   +1 more source

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

The FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari, Budheswar Dehury, Rounak Roy, Radhakrishnan Periyasamy, Indrashis Bhattacharya, Mahesh Sahare, Srinivasan Vijayraghavan, Souvik Dey   +7 more
wiley   +1 more source

Integrated volatile and non-volatile metabolomics reveal aroma chemotypes in Capsicum cultivars. [PDF]

Food Chem X
He L, Li H, Yin L, YangYi J, Ye C, Xia T, Zhang G, Li H, Li W, Wu T.   +9 more
europepmc   +1 more source

Seasonal variation in preen gland secretions of Tristram's Storm Petrel (Hydrobates tristrami)

Ibis, EarlyView.
Preen gland secretions are known to vary depending on sex, season and species and are thought to play essential roles in avian life history. However, their chemical composition and functions remain largely unclear in Procellariiform seabirds with well‐developed olfactory senses. Storm petrels, known for their distinctive body odour, may use preen gland
Taiki Terajima, Yutaka Yamamoto, Kentaro Nagaoka   +2 more
wiley   +1 more source

From Fatty Acid Precursors to Off-Odor in Canned Antarctic Krill: Matrix-Dependent Odorant Expression Under Retort Sterilization Conditions. [PDF]

Foods
Sun P, Lin S, Tan Y, Qin Y, Bi X, Li D.
europepmc   +1 more source

Benign by design: A paradigm shift in cosmetic ingredient development

International Journal of Cosmetic Science, EarlyView.
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota, Klaus Kümmerer, Isabel Martins de Almeida, Emília Sousa   +3 more
wiley   +1 more source

Identification of mitochondria-associated hub genes related to alcohol-associated liver fibrosis progression in aldehyde dehydrogenase 2 deficiency. [PDF]

Front Physiol
Zhang F, Gao Y.
europepmc   +1 more source