Results 1 to 10 of about 1,358,366 (163)

Studying fatty aldehyde metabolism in living cells with pyrene-labeled compounds [PDF]

Journal of Lipid Research, 2012
The lack of fatty aldehyde dehydrogenase function in Sjögren Larsson Syndrome (SLS) patient cells not only impairs the conversion of fatty aldehydes into their corresponding fatty acid but also has an effect on connected pathways. Alteration of the lipid
Markus A. Keller, Katrin Watschinger, Karsten Lange, Georg Golderer, Gabriele Werner-Felmayer, Albin Hermetter, Ronald J.A. Wanders, Ernst R. Werner   +7 more
doaj   +7 more sources

Monitoring of fatty aldehyde dehydrogenase by formation of pyrenedecanoic acid from pyrenedecanal

Journal of Lipid Research, 2010
Fatty aldehyde dehydrogenase (EC 1.2.1.48) converts long-chain fatty aldehydes to the corresponding acids. Deficiency in this enzyme causes the Sjogren Larsson Syndrome, a rare inherited disorder characterized by ichthyosis, spasticity, and mental ...
Markus A. Keller, Katrin Watschinger, Georg Golderer, Manuel Maglione, Bettina Sarg, Herbert H. Lindner, Gabriele Werner-Felmayer, Alessandro Terrinoni, Ronald J.A. Wanders, Ernst R. Werner   +9 more
doaj   +4 more sources

Fatty acid metabolism-related genes are associated with flavor-presenting aldehydes in Chinese local chicken

Frontiers in Genetics, 2022
Aldehydes are primary volatile organic compounds (VOCs) in local Chinese chicken meat and contribute green grass, fatty, citrus, and bitter almond aromas to chicken meat. To understand the genetic basis of these aldehyde VOC aromas, we used approximately
Xiaoya Yuan, Huanxian Cui, Yuxi Jin, Wenjuan Zhao, Xiaojing Liu, Yongli Wang, Jiqiang Ding, Li Liu, Jie Wen, Guiping Zhao   +9 more
doaj   +3 more sources

Fatty aldehyde and fatty alcohol metabolism: Review and importance for epidermal structure and function [PDF]

Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids, 2014
Normal fatty aldehyde and alcohol metabolism is essential for epidermal differentiation and function. Long-chain aldehydes are produced by catabolism of several lipids including fatty alcohols, sphingolipids, ether glycerolipids, isoprenoid alcohols and certain aliphatic lipids that undergo α- or ω-oxidation.
William Rizzo
exaly   +3 more sources

Fatty aldehyde dehydrogenases in Acinetobacter sp. strain HO1-N: role in hexadecanol metabolism. [PDF]

Journal of Bacteriology, 1985
The role of fatty aldehyde dehydrogenases (FALDHs) in hexadecane and hexadecanol metabolism was studied in Acinetobacter sp. strain HO1-N. Two distinct FALDHs were demonstrated in Acinetobacter sp. strain HO1-N: a membrane-bound, NADP-dependent FALDH activity induced 5-, 15-, and 9-fold by growth on hexadecanol, dodecyl aldehyde, and hexadecane ...
W R Finnerty
exaly   +3 more sources

Sjögren-Larsson syndrome: A biochemical rationale for using aldehyde-reactive therapeutic agents

Molecular Genetics and Metabolism Reports, 2022
Sjögren-Larsson syndrome (SLS) is a neurocutaneous disease caused by mutations in ALDH3A2 that result in deficient fatty aldehyde dehydrogenase (FALDH) activity and impaired fatty aldehyde and fatty alcohol oxidation.
William B. Rizzo, Dana S'aulis, Elizabeth Dorwart, Zachary Bailey   +3 more
doaj   +1 more source

Untargeted Metabolomic Analysis of Sjögren–Larsson Syndrome Reveals a Distinctive Pattern of Multiple Disrupted Biochemical Pathways

Metabolites, 2023
Sjögren–Larsson syndrome (SLS) is a rare inherited neurocutaneous disease characterized by ichthyosis, spastic diplegia or tetraplegia, intellectual disability and a distinctive retinopathy.
Hongying Daisy Dai, Fang Qiu, Kimberly Jackson, Marcus Fruttiger, William B. Rizzo   +4 more
doaj   +1 more source

TRP Channels as Sensors of Aldehyde and Oxidative Stress

Biomolecules, 2021
The transient receptor potential (TRP) cation channel superfamily comprises more than 50 channels that play crucial roles in physiological processes. TRP channels are responsive to several exogenous and endogenous biomolecules, with aldehydes emerging as
Katharina E. M. Hellenthal, Laura Brabenec, Eric R. Gross, Nana-Maria Wagner   +3 more
doaj   +1 more source

Omics Sequencing of Saccharomyces cerevisiae Strain with Improved Capacity for Ethanol Production

Fermentation, 2023
Saccharomyces cerevisiae is the most important industrial microorganism used to fuel ethanol production worldwide. Herein, we obtained a mutant S. cerevisiae strain with improved capacity for ethanol fermentation, from 13.72% (v/v for the wild-type ...
Zhilong Lu, Ling Guo, Xiaoling Chen, Qi Lu, Yanling Wu, Dong Chen, Renzhi Wu, Ying Chen   +7 more
doaj   +1 more source

METABOLIC FUNCTION OF BRANCHED-CHAIN VOLATILE FATTY ACIDS, GROWTH FACTORS FOR RUMINOCOCCI II [PDF]

Journal of Bacteriology, 1962
Allison , M. J. (Dairy Cattle Research Branch, USDA, Beltsville, Md.), M. P. Bryant, I. Katz, and M. Keeney . Metabolic function of branched-chain volatile fatty acids, growth factors for ruminococci. II. Biosynthesis of higher branched-chain fatty acids and aldehydes. J. Bacteriol. 83:
M J, ALLISON, M P, BRYANT, I, KATZ, M, KEENEY   +3 more
openaire   +2 more sources