Results 41 to 50 of about 1,358,366 (163)

Abscisic Acid Deficiency Alters Epicuticular Wax Metabolism and Morphology That Leads to Increased Cuticle Permeability During Sweet Orange (Citrus sinensis) Fruit Ripening

Frontiers in Plant Science, 2020
Citrus fruit ripening is coupled with the synthesis and deposition of epicuticular waxes, which reduces water loss during fruit postharvest storage.
Paco Romero, María Teresa Lafuente
doaj   +1 more source

Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. [PDF]

, 2004
BACKGROUND: Some animal studies have suggested that conjugated linoleic acid (CLA) supplementation may have therapeutic potential with respect to insulin sensitivity and lipid metabolism, which are important cardiovascular disease (CVD) risk factors ...
Mullen, Anne, Anne Mullen, John J Nolan, Moloney, F, Yeow, Toh-Peng, Toh-Peng Yeow, Helen M Roche, Yeow, TP, Roche, HM, Fiona Moloney, Mullen, A, Nolen, JJ, Moloney, Fiona, Nolan, John J, Roche, Helen M   +14 more
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Effect of animal and industrial trans fatty acids on HDL and LDL cholesterol levels in humans - a quantitative review [PDF]

, 2010
Background: Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower HDL cholesterol, raise LDL cholesterol, and increase the risk of coronary heart ...
Wanders Anne J., Brouwer, I.A.; id_orcid, Martijn B. Katan, Katan Martijn B., Martijn B Katan, Ingeborg A Brouwer, Anne J. Wanders, Brouwer, I.A., Katan, M.B.; id_orcid, Katan, M.B., Anne J Wanders, Wanders, A.J., Ingeborg A. Brouwer, Brouwer Ingeborg A.   +13 more
core   +4 more sources

How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome

Lipids in Health and Disease, 2006
Introduction Herein, we expand our previous work on the effects of long chain polyunsaturated fatty acids (LC-PUFA) on the murine hepatic transcriptome using novel statistical and bioinformatic approaches for evaluating microarray data.
Roberts Matthew A, Berger Alvin, Hoff Bruce   +2 more
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Establishment of the tree shrew as an alcohol-induced Fatty liver model for the study of alcoholic liver diseases. [PDF]

PLoS ONE, 2015
Currently, the pathogenesis of alcoholic liver diseases (ALDs) is not clear. As a result, there is no effective treatment for ALDs. One limitation is the lack of a suitable animal model for use in studying ALDs.
Huijie Xing, Kun Jia, Jun He, Changzheng Shi, Meixia Fang, Linliang Song, Pu Zhang, Yue Zhao, Jiangnan Fu, Shoujun Li   +9 more
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Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry

Biomolecules, 2022
Aiming to elucidate the system-wide effects of the alcohol-induced increase in the content of cytochrome P450 2E1 (CYP2E1) on drug metabolism, we explored the array of its protein-protein interactions (interactome) in human liver microsomes (HLM) with ...
Dmitri R. Davydov, Bikash Dangi, Guihua Yue, Deepak S. Ahire, Bhagwat Prasad, Victor G. Zgoda   +5 more
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Targeting Hepatic Protein Carbonylation and Oxidative Stress Occurring on Diet-Induced Metabolic Diseases through the Supplementation with Fish Oils

Marine Drugs, 2018
The present study addressed the ability of long-chain ω-3 polyunsaturated fatty acids (ω-3 PUFA), i.e., eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), to ameliorate liver protein damage derived from oxidative stress and induced ...
Silvia Muñoz, Lucía Méndez, Gabriel Dasilva, Josep Lluís Torres, Sara Ramos-Romero, Marta Romeu, María Rosa Nogués, Isabel Medina   +7 more
doaj   +1 more source

Supplementation with n-3 long-chain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells [PDF]

, 2014
BACKGROUND: Studies in animal models and in cultured cells have shown that fatty acids can induce alterations in the DNA methylation of specific genes. There have been no studies of the effects of fatty acid supplementation on the epigenetic regulation ...
Burdge, Graham C., Mori, T.A., Karen A Lillycrop, Samuel P Hoile, Rebecca Clarke-Harris, Clarke-Harris, R., Graham C Burdge, Beilin, L.J., Philip C Calder, Lawrence J Beilin, Calder, P.C., Huang, R.C., Lillycrop, Karen A., Trevor A Mori, Hoile, Samuel P., Rae-Chi Huang   +15 more
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The role of bacterial metabolites derived from aromatic amino acids in non-alcoholic fatty liver disease

Alʹmanah Kliničeskoj Mediciny, 2020
The review deals with the role of aromatic amino acids and their microbial metabolites in the development and progression of non-alcoholic fatty liver disease (NAFLD).
E. S. Shcherbakova, T. S. Sall, S. I. Sitkin, T. Ya. Vakhitov, E. V. Demyanova   +4 more
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miR-1182-mediated ALDH3A2 inhibition affects lipid metabolism and progression in ccRCC by activating the PI3K-AKT pathway

Translational Oncology
In clear cell renal cell carcinoma (ccRCC), dysregulated lipid metabolism plays a pivotal role in tumor initiation and progression. This study delves into the unexplored landscape of Dysregulated Aldehyde Dehydrogenase 3 Family Member A2 (ALDH3A2) in ...
Qingyang Lv, Jian Shi, Daojia Miao, Diaoyi Tan, Chuanyi Zhao, Zhiyong Xiong, Xiaoping Zhang   +6 more
doaj   +1 more source