Results 1 to 10 of about 2,830,510 (203)
Mechanisms and disease consequences of nonalcoholic fatty liver disease.
Cell, 2021 Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver injury that can lead to cirrhosis and hepatocellular carcinoma.
R. Loomba, S. Friedman, G. Shulman
semanticscholar +3 more sources
Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease.
New England Journal of Medicine, 2021 BACKGROUND The prognoses with respect to mortality and hepatic and nonhepatic outcomes across the histologic spectrum of nonalcoholic fatty liver disease (NAFLD) are not well defined.
A. Sanyal +16 more
semanticscholar +3 more sources
A multi-society Delphi consensus statement on new fatty liver disease nomenclature.
Journal of Hepatology, 2023 The principal limitations of the terms nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are the reliance on exclusionary confounder terms and the use of potentially stigmatising language. This study set out to determine if
M. Rinella +52 more
semanticscholar +2 more sources
陆军军医大学学报, 2023 Objective To explore the effect and molecular mechanism of artesunate (ART) on cholestatic liver fibrosis induced by 3, 5-diethoxycarbonyl-1, 4-dihydro-2, 4, 6-collidine (DDC).
TANG Wan +3 more
doaj +1 more source
Hepatology, 2023 Background and Aims: NAFLD is a leading cause of liver-related morbidity and mortality. We assessed the global and regional prevalence, incidence, and mortality of NAFLD using an in-depth meta-analytic approach.
Z. Younossi +5 more
semanticscholar +1 more source
陆军军医大学学报, 2023 Objective To screen and verify the Hub genes involved in conjugated bile acid-induced hepatocyte metabolism through transcriptome sequencing analysis. Methods Primary mouse hepatocytes were treated with taurocholic acid (TCA), and the gene expression of ...
ZHANG Mengni +4 more
doaj +1 more source
Frontiers in Nutrition, 2022 Recent studies have revealed that sarcopenia is closely associated with obesity and non-alcoholic steatohepatitis (NASH). However, few attempted to explore the cause-and-effect relationship between sarcopenic obesity and NASH.
Zi-Xuan Wang +9 more
doaj +1 more source
Carrier-free curcumin nanoassemblies for enhancing therapy effects in inflammation related disease
Materials & Design, 2022 Hyperinflammation can lead to tissue injury, organ failure, and even fatalities by overproducing proinflammatory cytokines. The long-term safety and outstanding anti-inflammatory ability of natural products have attracted much attention, but the low ...
Liangjun Zhang +9 more
doaj +1 more source
Journal of Hepatology, 2020 The exclusion of other chronic liver diseases including "excess" alcohol intake has till now been necessary to establish a diagnosis of metabolic-dysfunction-associated fatty liver disease (MAFLD).
M. Eslam +29 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2023 To date, non-alcoholic fatty liver disease (NAFLD) is the most frequent liver disease, affecting up to 70% of patients with diabetes. Currently, there are no specific drugs available for its treatment.
R. Nevola +8 more
semanticscholar +1 more source