The role of lipid and lipoprotein metabolism in non-alcoholic fatty liver disease [PDF]
, 2017 Due to the epidemic of obesity across the world, nonalcoholic fatty liver disease (NAFLD) has become one of the most prevalent chronic liver disorders in children and adolescents.
Anania, Caterina +4 more
core +2 more sources
Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway. [PDF]
, 2008 The liver is responsible for key metabolic functions, including control of normal homoeostasis in response to diet and xenobiotic metabolism/detoxification.
Finn, Robert +3 more
core +4 more sources
Cellular and Molecular Gastroenterology and Hepatology, 2023 Background & Aims: OATP1B3/SLCO1B3 is a human liver-specific transporter for the clearance of endogenous compounds (eg, bile acid [BA]) and xenobiotics.
Qiong Pan +16 more
doaj +1 more source
To identify and examine the different causes of liver disease in Sri Lanka [PDF]
, 2017 © 2017 The Authors. Published by International Journal of Science and Research. This is an open access article available under a Creative Commons licence.
Aslam, Fahim, Kulasena, Hashan
core +1 more source
Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. [PDF]
, 2017 Disruption of hepatocyte growth hormone (GH) signaling through disruption of Jak2 (JAK2L) leads to fatty liver. Previously, we demonstrated that development of fatty liver depends on adipocyte GH signaling.
Camporez, João Paulo G +10 more
core +1 more source
Gastro Hep Advances, 2023 Background and Aims: Recent studies reported that the hepatic expression of AQP8 and AQP9 was downregulated in bile duct-ligated (BDL) rats and that overexpression of human AQP1 in the rat liver attenuated cholestasis.
Min Liao +10 more
doaj +1 more source
Metabolic profiling of fatty liver in young and middle-aged adults : Cross-sectional and prospective analyses of the Young Finns Study [PDF]
, 2016 Nonalcoholic fatty liver is associated with obesity-related metabolic disturbances, but little is known about the metabolic perturbations preceding fatty liver disease. We performed comprehensive metabolic profiling to assess how circulating metabolites,
Ala-Korpela, Mika +15 more
core +5 more sources
The effect of 12 weeks regular physical activity and vitamin E in the treatment of non-alcoholic steatohepatitis: A pilot study [PDF]
, 2015 Background: Despite the prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH), there was no treatment has been proven to be effective in these common diseases.
Eslami, L. +5 more
core +7 more sources
Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium. [PDF]
, 2019 ObjectivePopulations of Mexican American ancestry are at an increased risk for nonalcoholic fatty liver disease. The objective of this study was to determine whether loci in known and novel genes were associated with variation in aspartate ...
Chen, Yii-Der I +15 more
core +2 more sources
DNA Hydroxymethylation at the Interface of the Environment and Nonalcoholic Fatty Liver Disease. [PDF]
, 2019 Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent forms of chronic liver disorders among adults, children, and adolescents, and a growing epidemic, worldwide.
Besaratinia, Ahmad, Tommasi, Stella
core +1 more source