Results 21 to 30 of about 764,021 (214)

Organic Anion Transporting Polypeptide (OATP) 1B3 is a Significant Transporter for Hepatic Uptake of Conjugated Bile Acids in HumansSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: OATP1B3/SLCO1B3 is a human liver-specific transporter for the clearance of endogenous compounds (eg, bile acid [BA]) and xenobiotics.
Qiong Pan   +16 more
doaj   +1 more source

To identify and examine the different causes of liver disease in Sri Lanka [PDF]

open access: yes, 2017
© 2017 The Authors. Published by International Journal of Science and Research. This is an open access article available under a Creative Commons licence.
Aslam, Fahim, Kulasena, Hashan
core   +1 more source

The role of lipid and lipoprotein metabolism in non-alcoholic fatty liver disease [PDF]

open access: yes, 2017
Due to the epidemic of obesity across the world, nonalcoholic fatty liver disease (NAFLD) has become one of the most prevalent chronic liver disorders in children and adolescents.
Anania, Caterina   +4 more
core   +2 more sources

Hepatic Aquaporin 10 Expression Is Downregulated by Activated NFκB Signaling in Human Obstructive Cholestasis

open access: yesGastro Hep Advances, 2023
Background and Aims: Recent studies reported that the hepatic expression of AQP8 and AQP9 was downregulated in bile duct-ligated (BDL) rats and that overexpression of human AQP1 in the rat liver attenuated cholestasis.
Min Liao   +10 more
doaj   +1 more source

Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway. [PDF]

open access: yes, 2008
The liver is responsible for key metabolic functions, including control of normal homoeostasis in response to diet and xenobiotic metabolism/detoxification.
Finn, Robert   +3 more
core   +4 more sources

DNA Hydroxymethylation at the Interface of the Environment and Nonalcoholic Fatty Liver Disease. [PDF]

open access: yes, 2019
Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent forms of chronic liver disorders among adults, children, and adolescents, and a growing epidemic, worldwide.
Besaratinia, Ahmad, Tommasi, Stella
core   +1 more source

Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. [PDF]

open access: yes, 2017
Disruption of hepatocyte growth hormone (GH) signaling through disruption of Jak2 (JAK2L) leads to fatty liver. Previously, we demonstrated that development of fatty liver depends on adipocyte GH signaling.
Camporez, João Paulo G   +10 more
core   +1 more source

Sodium Butyrate Supplementation Inhibits Hepatic Steatosis by Stimulating Liver Kinase B1 and Insulin-Induced GeneSummary

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2021
Background and Aims: Butyric acid is an intestinal microbiota-produced short-chain fatty acid, which exerts salutary effects on alleviating nonalcoholic fatty liver disease (NAFLD).
Ze-Hua Zhao   +21 more
doaj   +1 more source

Targeting Thyroid Hormone/Thyroid Hormone Receptor Axis: An Attractive Therapy Strategy in Liver Diseases

open access: yesFrontiers in Pharmacology, 2022
Thyroid hormone/thyroid hormone receptor (TH/TR) axis is characterized by TH with the assistance of plasma membrane transporters to combine with TR and mediate biological activities.
Qianyu Tang   +4 more
doaj   +1 more source

Gut metabolomics and 16S rRNA sequencing analysis of the effects of arecoline on non-alcoholic fatty liver disease in rats

open access: yesFrontiers in Pharmacology, 2023
Introduction: Non-alcoholic fatty liver disease (NAFLD) has gradually become the primary cause of fatty liver disease. Betel nuts have been used to treat gastrointestinal diseases.Methods: In the present study, we analyzed the pathology, serology, gut ...
Lingping Zhu   +4 more
doaj   +1 more source

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