Results 91 to 100 of about 6,127,399 (262)

What is non-alcoholic fatty liver disease (NAFLD), and why is it important?

, 2015
Fatty liver is defined pathologically by stainable fat in hepatocytes (steatosis), or biochemically by hepatic triglyceride content exceeding 5.5%. Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent disorder in which over-nutrition leads to
McCullough, Arthur, Day, Christopher, Farrell, Geoffrey   +2 more
core  

Fatty liver disease in children: modern paradigms

Лечащий Врач
Background. Fatty liver disease is a term that combines pathological conditions, the common feature of which is the accumulation of lipids in the liver.
Anna S. Bevz, Tatyana A. Bokova
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A time to act: improving liver health and outcomes in liver disease

, 2009
A report prepared by the British Association for the Study of the Liver (BASL) and the British Society of Gastroenterology (BSG) Liver ...
Sheron, Nick
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Postprandial Dysmetabolism and Non-Alcoholic Fatty Liver Disease in Relation to Type 2 Diabetes Mellitus and Cardiovascular Risk [PDF]

, 2007
Het aantal gevallen van “ouderdomssuikerziekte” (type 2 diabetes mellitus) neemt in de Westerse wereld snel toe als gevolg van veranderingen in leefstijl (verhoogde consumptie van vet- en energierijke voeding en verminderde lichaamsbeweging), en als ...
Schindhelm, R.K.
core   +5 more sources

Features of therapeutic options for the treatment of non-alcoholic fatty liver disease and carbohydrate metabolism disorders

Лечащий Врач
Background. Diabetes mellitus is one of the most common diseases worldwide, and non-alcoholic fatty liver disease is recognized as the most common chronic liver disease worldwide.
N. A. Petunina, M. E. Telnova, E. V. Goncharova, I. A. Kuzina   +3 more
doaj   +1 more source

The association of vitamin D deficiency with non-alcoholic fatty liver disease

Clinics, 2014
OBJECTIVE: Vitamin D deficiency has been related to diabetes, hypertension, hyperlipidemia and peripheral vascular disease. In this study, we aimed to investigate the role of vitamin D status in non-alcoholic fatty liver disease.
Metin Küçükazman, Naim Ata, Kür?at Dal, Abdullah Özgür Yeniova, Ay?e Kefeli, Sebahat Basyigit, Bora Aktas, Kadir Okhan Akin, Kadir A?ladio?lu, Öznur Sari Üre, Firdes Topal, Ya?ar Nazligül, Esin Beyan, Derun Taner Ertugrul   +13 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Serum osteopontin levels as a predictor of portal inflammation in patients with nonalcoholic fatty liver disease

, 2013
Background: Osteopontin is a secreted phosphorylated glycoprotein that is expressed by a variety of cell types and that mediates numerous and diverse biological functions. Osteopontin knockout mice are protected from obesity-induced hepatic steatosis. In
ÖZEN ALAHDAB, YEŞİM, ATUĞ, ÖZLEN, EREN, FATİH, YILMAZ, YUSUF   +3 more
core   +1 more source