Results 71 to 80 of about 6,127,399 (262)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Hepatoprotective properties of Gentiana SPP: Against non-alcoholic fatty liver disease (NAFLD) [PDF]
, 2018 Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease characterised by the accumulation of fat in the liver. It is estimated that 33 % of the UK population have NAFLD with 2-5 % progressing to non-alcoholic steatohepatitis (NASH).
Boateng, A.
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 2008 Background. Visceral adiposity is the major risk factor for paediatric nonalcoholic fatty liver disease. Aims. Determine the prevalence of nonalcoholic fatty liver disease according to the visceral fat quartile. Subjects.
Prado, Wagner Luiz do [UNIFESP] +10 more
core +1 more source
Now, CMFRI Comes Up With Natural Remedy For Fatty Liver Disease Suchana News dated 27th September 2022 [PDF]
, 2022 In continuation of its major research work on developing natural remedies from marine organisms against various lifestyle diseases, the Central Marine Fisheries Research Institute (CMFRI) has come up with a nutraceutical product from select seaweeds to ...
CMFRI, Library
core +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
, 2015 Introduction. Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases where its frequency in the population varies within 3.0–40.0 %.
Mashura H., Hanych T.
core +1 more source
Performance of Biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in Patients with Severe Obesity: Meta Analysis of Individual Patient Data [PDF]
, 2012 Background Liver biopsy is considered as the gold standard for assessing non-alcoholic fatty liver disease (NAFLD) histologic lesions in patients with severe obesity.
Mathurin, Philippe +60 more
core +2 more sources
Journal of Lipid and AtherosclerosisMetabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) are significant health concerns affecting a large segment of the population and are known to be associated with adverse ...
Walter Masson +2 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source