Results 61 to 70 of about 14,817 (259)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Research of Fault Line Selection Method of Distribution Network Based on Transient Zero-sequence Energy

Gong-kuang zidonghua, 2012
For problem of ineffectiveness of traditional line selection methods by use of single feature value caused by complex and random fault borderline, small steady component of fault and reverse phase of instantaneous zero-sequence power when single-phase ...
TIAN Shu, HE Jin-peng, NIE He
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Dancing on the Fault Lines of History

Dancing on the Fault Lines of History collects essential essays by Susan Manning, one of the founders of critical dance studies, recounting her career writing and rewriting the history of modern dance. Three sets of keywords—gender and sexuality, whiteness and Blackness, nationality and globalization—illuminate modern dance histories from multiple ...
openaire   +3 more sources

Single-phase earth fault line selection method based on ICEEMAN grid

, 2022
Abstract The neutral resonant grounding system occurs when the single-phase ground fault redundant fault information and the traditional fault routing party to the fault signal characteristics of the poor degree of self-adaptive extraction, routing accuracy is low and other problems.
Ming Lu, Zezhong Liu, Xianke He, Zuguo Chen, Ying Zou   +4 more
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

A New Method for Fault Line Selection of Photovoltaic Power Station Collection Lines Based on TEO Energy

Zhongguo dianli
Carrying out rapid fault selection of PV power station collection lines is of great significance to ensure the stable operation of the system. A fault method for PV power station collection lines based on the zero-sequence current gradient Teager energy ...
Ran ZHENG, Jiayi WU, Haoliang DU, Wulue PAN   +3 more
doaj   +1 more source

Fault line selection method for distribution network based on measurement of characteristic atom

Gong-kuang zidonghua, 2017
For problems that fault feature extraction was not enough and fault line selection criterion needs samples with long training time in existing fault line selection methods for distribution network, a fault line selection method for distribution network ...
ZHAO Liang, ZHOU Nuoying, WANG Xiaowei
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A Single-Phase Ground Fault Line Selection Method in Active Distribution Networks Based on Transformer Grounding Mode Modification

Energies
Reliable fault line selection technology is crucial for preventing fault range expansion and ensuring the reliable operation of distribution networks.
Shi Su, Qingyang Xie, Pengfei Ma, Yuan Li, Fahui Chen, Jing Zhang, Botong Li, Changqi Wang   +7 more
doaj   +1 more source