Results 81 to 90 of about 14,817 (259)

Injection Current Distribution Characteristics Identification Based Distribution-Level Fault Line Selection

open access: yesZhongguo dianli
Addressing the challenges posed by the subtle characteristics of single-phase grounding faults in resonant grounding systems, which lead to decreased sensitivity and reliability in fault line selection methods reliant on these characteristics, an ...
Xiaowei WANG   +6 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Research on fault line selection method based on steady state variables

open access: yesAIP Advances
When a single-phase ground fault occurs, the transient zero sequence current will significantly increase. So, it is possible to detect whether a single-phase grounding fault has occurred in the transmission line by calculating and comparing the amplitude of transient zero sequence current.
Sha Wang, Changsheng Liu, Shengkai Wei
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Differential Protection of Distribution Network Based on VMD and Duffing Oscillator

open access: yesZhongguo dianli
The distribution network is grounded through arc suppression coil. When a single-phase grounding fault occurs, the faulting characteristics are often weak and unobvious, which makes it difficult to accurately locate the fault line.
Jianbao ZHANG, Lei WANG, Weijian JIANG
doaj   +1 more source

Time-Frequency Transformation Technique with Various Mother Wavelets for DC Fault Analysis in HVDC Transmission Systems

open access: yesSir Syed University Research Journal of Engineering and Technology, 2023
HVDC transmission has become a cost-effective option for transferring high voltage over greater distances. Protecting an HVDC transmission line is more challenging than protecting an AC transmission line due to its low impedance and absence of zero ...
Hasnain Raza chandio, Aslam Pervez Memon
doaj  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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