Results 91 to 100 of about 395,992 (296)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A New Method for Fault Line Selection of Photovoltaic Power Station Collection Lines Based on TEO Energy

Zhongguo dianli
Carrying out rapid fault selection of PV power station collection lines is of great significance to ensure the stable operation of the system. A fault method for PV power station collection lines based on the zero-sequence current gradient Teager energy ...
Ran ZHENG, Jiayi WU, Haoliang DU, Wulue PAN   +3 more
doaj   +1 more source

Teaching old sensors New tricks: archetypes of intelligence

, 2007
In this paper a generic intelligent sensor software architecture is described which builds upon the basic requirements of related industry standards (IEEE 1451 and SEVA BS- 7986). It incorporates specific functionalities such as real-time fault detection,
Chorti, Arsenia, Harris, Chris J., Karatzas, Dimosthenis, White, Neil M.   +3 more
core  

Identifying Bugs in Make and JVM-Oriented Builds

, 2020
Incremental and parallel builds are crucial features of modern build systems. Parallelism enables fast builds by running independent tasks simultaneously, while incrementality saves time and computing resources by processing the build operations that ...
Chaliasos, Stefanos, Mitropoulos, Dimitris, Sotiropoulos, Thodoris, Spinellis, Diomidis   +3 more
core  

A Taxonomy of model-based testing [PDF]

, 2006
Model-based testing relies on models of a system under test and/or its environment to derive test cases for the system. This paper provides an overview of the field.
Legeard, Bruno, Pretschner, Alexander, Utting, Mark   +2 more
core  

Event-based Failure Prediction in Distributed Business Processes

, 2018
Traditionally, research in Business Process Management has put a strong focus on centralized and intra-organizational processes. However, today's business processes are increasingly distributed, deviating from a centralized layout, and therefore calling ...
Borkowski, Michael, Fdhila, Walid, Nardelli, Matteo, Rinderle-Ma, Stefanie, Schulte, Stefan   +4 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A Single-Phase Ground Fault Line Selection Method in Active Distribution Networks Based on Transformer Grounding Mode Modification

Energies
Reliable fault line selection technology is crucial for preventing fault range expansion and ensuring the reliable operation of distribution networks.
Shi Su, Qingyang Xie, Pengfei Ma, Yuan Li, Fahui Chen, Jing Zhang, Botong Li, Changqi Wang   +7 more
doaj   +1 more source

A fault line selection method of small current grounding system based on wavelet de-noising and improved RBF neural network

Gong-kuang zidonghua, 2014
The paper proposed a fault line selection method of small current grounding system based on wavelet de-noising and improved RBF neural network. Fault information matrix is obtained after normalization processing for maximum of absolute value of de-noised
WANG Xiaowei, WEI Xiangxiang, HOU Yaxiao, GAO Jie   +3 more
doaj   +1 more source

Single-phase earth fault line selection method based on ICEEMAN grid

, 2022
Abstract The neutral resonant grounding system occurs when the single-phase ground fault redundant fault information and the traditional fault routing party to the fault signal characteristics of the poor degree of self-adaptive extraction, routing accuracy is low and other problems.
Ming Lu, Zezhong Liu, Xianke He, Zuguo Chen, Ying Zou   +4 more
openaire   +1 more source