Results 11 to 20 of about 446,586 (304)
Obtaining Boiler Fuel Gas to Reduce Air Pollution: The Policy of the Federal Power Commission [PDF]
, 1968 Receptors interacting with the constant domain of immunoglobulins (Igs) have a number of important functions in vertebrates. They facilitate phagocytosis by opsonization, are key components in antibody-dependent cellular cytotoxicity as well as ...
Akula, Srinivas +2 more
core +4 more sources
Fc Binding by FcγRIIa Is Essential for Cellular Activation by the Anti-FcγRIIa mAbs 8.26 and 8.2
Frontiers in Immunology, 2021 FcγR activity underpins the role of antibodies in both protective immunity and auto-immunity and importantly, the therapeutic activity of many monoclonal antibody therapies.
Bruce D. Wines +15 more
doaj +1 more source
pH Dependence and Stoichiometry of Binding to the Fc Region of IgG by the Herpes Simplex Virus Fc Receptor gE-gI [PDF]
, 2004 Herpes simplex virus type 1 encodes two glycoproteins, gE and gI, that form a heterodimer on the surface of virions and infected cells. The gE-gI heterodimer has been implicated in cell-to-cell spread of virus and is a receptor for the Fc fragment of IgG.
Bjorkman, Pamela J. +2 more
core +1 more source
Annual Review of Immunology, 2003 The IgA receptor family comprises a number of surface receptors including the polymeric Ig receptor involved in epithelial transport of IgA/IgM, the myeloid specific IgA Fc receptor (FcαRI or CD89), the Fcα/μR, and at least two alternative IgA receptors.
Monteiro, R.C., van de Winkel, J.G.J.
openaire +3 more sources
, 2008 The aggregation of cell surface Fc receptors by immune complexes induces a number of important antibody-dependent effector functions. It is becoming increasingly evident that the organization of key immune proteins has a significant impact on the function of these proteins.
Maree S, Powell, P Mark, Hogarth
+6 more sources
Enhanced metabolism of LDL aggregates mediated by specific human monocyte IgG Fc receptors.
Journal of Lipid Research, 1995 Macrophage-derived foam cells are important constituents of atheromatous lesions. In addition to the scavenger receptor pathway, uptake of immune complexed lipoproteins through IgG Fc receptors (Fc gamma receptors) represents an additional pathway of ...
P M Morganelli +3 more
doaj +1 more source
Journal of Extracellular Vesicles, 2020 Production of extracellular vesicles (EVs) involved in intercellular communication is a common capacity of most cell types. Upon encountering opsonized microorganisms, neutrophilic granulocytes release EVs that compromise bacterial growth. We carried out
Ákos M. Lőrincz +11 more
doaj +1 more source
Expression, Purification, and Biophysical Characterization of a Secreted Anthrax Decoy Fusion Protein in Nicotiana benthamiana. [PDF]
, 2017 Anthrax toxin receptor-mediated drug development for blocking anthrax toxin action has received much attention in recent decades. In this study, we produced a secreted anthrax decoy fusion protein comprised of a portion of the human capillary ...
Dandekar, Abhaya M +8 more
core +2 more sources
mAbs, 2019 The neonatal Fc receptor (FcRn) promotes antibody recycling through rescue from normal lysosomal degradation. The binding interaction is pH-dependent with high affinity at low pH, but not under physiological pH conditions.
Brian C. Mackness +11 more
doaj +1 more source
Electron tomography of late stages of FcRn-mediated antibody transcytosis in neonatal rat small intestine [PDF]
, 2012 The neonatal Fc receptor (FcRn) transports maternal immunoglobulin (IgG) across epithelia to confer passive immunity to mammalian young. In newborn rodents, FcRn transcytoses IgG from ingested milk across the intestinal epithelium for release into the ...
Bjorkman, Pamela J. +2 more
core +2 more sources