Results 161 to 170 of about 2,051 (177)

Functional polymorphisms in the FCN2 gene are not associated with invasive pneumococcal disease.

Molecular Immunology, 2007
L-ficolin is a pattern-recognition molecule which binds lipoteichoic acid and Gram-positive bacteria and activates the lectin pathway of complement. Five common functional polymorphisms have recently been identified in the FCN2 gene which encodes L-ficolin: three promoter polymorphisms (at positions -986, -602 and -4) which affect serum L-ficolin ...
S. Chapman, F. Vannberg, C. Khor, S. Segal, C. Moore, K. Knox, N. Day, R. Davies, D. Crook, A. Hill   +9 more
semanticscholar   +3 more sources

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Ficolin-2 and FCN2 in patients with systemic inflammation

Molecular Immunology, 2011
L. Munthe-Fog, D. Hellemann, J. Bonde, P. Garred   +3 more
semanticscholar   +2 more sources

FCN2 c.772G>T polymorphism is associated with chronic adenoiditis and/or tonsillitis, but not -4 A>G and -602 G>A.

International Journal of Pediatric Otorhinolaryngology, 2016
Ficolins are complement activating peptides that play a role in the initial host defense against infectious pathogens. In the present study, we investigated the relationship between single nucleotide polymorphisms (SNPs) in the ficolin 2 gene (FCN2) and chronic adenotonsillitis in pediatric cases.Case-control study.A total of 101 pediatric patients ...
A. Erkan, I. Oz, Y. Terzi, E. Aydın, M. Ozkale, S. Babakurban, Alper Koycu, F. Sahin   +7 more
semanticscholar   +3 more sources

MBL2, FCN1, FCN2 and FCN3-The genes behind the initiation of the lectin pathway of complement.

Molecular Immunology, 2009
Mannose-binding lectin (MBL) and the ficolins (Ficolin-1, Ficolin-2 and Ficolin-3) are soluble collagen-like proteins that are involved in innate immune defence. They bind sugar structures or acetylated compounds present on microorganisms and on dying host cells and they initiate activation of the lectin complement pathway in varying degrees.
P. Garred, Christian Honoré, Y. Ma, L. Munthe-Fog, T. Hummelshøj   +4 more
semanticscholar   +4 more sources

Comparative Genomics and Functional Divergence of Ficolin-2 (FCN2) Across Various Types of Species: A Bioinformatics Approach

Southeast Asia´s Winter 2025 International Conference Proceedings PCSETE-25, PABES-25, BDATE-25, PICSEE-25, BS3HE-25, BICFET-25, BAMT-25 and SHSSM-25

semanticscholar   +2 more sources

The Lack of Association between FCN2 Gene Promoter Region Polymorphisms and Dental Caries in Polish Children

Caries Research, 2017
T. Olszowski, M. Milona, J. Janiszewska-Olszowska, Krzysztof Safranow, K. Skonieczna-Żydecka, A. Walczak, Maciej Sikora, D. Chlubek, A. Madlani, G. Adler   +9 more
semanticscholar   +2 more sources

SAT0498 MBL2 and the FCN2 Polymorphisms in a Group of Pediatric Subjects with Rheumatic Fever: A Case Control Study (Preliminary Data)

Annals of the Rheumatic Diseases, 2015
Background Human ficolins (FCN) and mannan-binding lectin (MBL2) are pattern-recognition proteins involved in innate immunity. It has been suggested a role for MBL2 and FCN2 gene polymorphisms in the pathogenesis of recurrent, severe streptococcal infections and rheumatic carditis. Objectives The aim of this study is to evaluate the presence of MBL2
C. Di Battista, V. Marzetti, L. Stuppia, R. Ferrante, M. Lucantoni, M. Marsili, L. Breda, F. Chiarelli   +7 more
semanticscholar   +2 more sources

Novel DNA alterations in FCN1 and FCN2 genes in atypical HUS patients

Molecular Immunology, 2011
E. Volokhina, D. Westra, A. Spoelstra, N. Kar, L. Heuvel   +4 more
semanticscholar   +2 more sources

[Effect of Mn2+ on pyrene degradation by Flavobacterium sp. FCN2].

Huan jing ke xue= Huanjing kexue, 2009
Mn2+ concentration affecting polycyclic aromatic hydrocarbon pyrene degradation by the Flavobacterium sp. FCN2 was investigated by adding Mn2+ during several periods, which including bacteria cultivation period, bacteria degrading pyrene and enzymatic degradation period.
Man-Li, Wu, Mai-Qian, Nie, Xiao-Chang, Wang, Jun-Mei, Su   +3 more
openaire   +1 more source

Association of FCN1 and FCN2 gene polymorphisms with earlier onset of chronic pseudomonas aeruginosa (Pa) colonisation in cystic fibrosis (CF) patients

European Respiratory Journal, 2011
Background: CF is a multisystem disease with high degree of phenotypic variability especially in lung disease.Modifying genes of innate immunity may be involved in early onset of Pa colonisation.
F. Haerynck, K. Steen, T. Cattaert, B. Loeys, S. Daele, P. Schelstraete, F. Baets   +6 more
semanticscholar   +1 more source