Results 161 to 170 of about 3,812 (172)

Impact of HIV-1 Tat on FDFT1 Suppression, Changes in Cholesterol Level, and KSHV Replication in BCBL1 Cells

Current HIV Research
Introduction: The present study investigated the molecular mechanism by which the transactivator of transcription (Tat) protein of Human Immunodeficiency Virus 1 (HIV-1) acti-vates the replication cycle of Kaposi's Sarcoma-associated Herpesvirus (KSHV). Methods: BCBL-1 cells were initially infected with lentivirus overexpressing HIV-1 Tat.
Qiaozhen Liu, Xiaoying Chen, Dewen Liu, Yuting Zou, Weiling Yang, Ziyi Cao, Yao Ding, Weihang Ji, Na Xiao, Huaying Tang, Yan Jiang, Liandeng Wei, Yi Zeng   +12 more
openaire   +1 more source

Artemisitene induces apoptosis of breast cancer cells by targeting FDFT1 and inhibits the growth of breast cancer patient-derived organoids

Phytomedicine
Artemisitene (ATT) is a natural bioactive compound with anti-breast cancer activity. However, the direct target and clinical efficacy of ATT on breast cancer are still unclear. The current study aimed to identify the target protein and underlying mechanism of ATT in anti-breast cancer.
Dong Chen, Guangxin Li, Lianxiang Luo, Tengyu Lin, Xinyu Chu, Kangdi Liu, Tianli Lai, Yinglin Liao, Xian Lin, Jian Chen   +9 more
openaire   +2 more sources

A piRNA chemosensitizes doxorubicin in tongue squamous cell carcinoma by targeting FDFT1 and inhibiting the EIF3H/HIF1α/CYPOR axis

Archives of Biochemistry and Biophysics
Doxorubicin (DOX) is a classical chemotherapeutic for various cancers that acts by intercalating within the DNA strand and inhibiting the function of topoisomerase, resulting in DNA break-induced apoptosis. Acquired chemoresistance has become a challenge for DOX therapy, but the possible solutions to overcome this problem are under investigation in ...
Trisha Chattopadhyay, Priyajit Biswal, Sruti Biswal, Bibekanand Mallick   +3 more
openaire   +2 more sources

684 NOVEL CANDIDATE GENE FOR PROSTATE CANCER (PC) SUSCEPTIBILITY, FARNECYL-DIPHOSPHATE FARNECYLTRANSFERASE 1 (FDFT1) : ASSOCIATIONS OF FDFT1 GENE VARIANTS WITH PC RISK, AND FDFT1 PROTEIN FUNCTION EVALUATION IN PC CELLS

Journal of Urology, 2010
Hiroshi Matsui, Yuji Fukuma, Tatsuya Hamano, Hidekazu Koike, Yoshitaka Sekine, Nobuaki Ohtake, Seiji Nakata, Kazuhiro Suzuki   +7 more
openaire   +1 more source

751 A NOVEL CANDIDATE GENE OF SUSCEPTIBILITY TO PROSTATE CANCER, FARNECYL-DIPHOSPHATE FARNECYLTRANSFERASE 1 (FDFT1) GENE: ASSOCIATION BETWEEN THE VARIANTS OF THE FDFT1 GENE AND THE PROSTATE CANCER RISK, AND THE EVALUATION OF THE FDFT1 PROTEIN FUNCTION TO THE PROSTATE CANCER CELLS

European Urology Supplements, 2010
H. Matsui, Y. Fukuma, T. Hamano, H. Koike, Y. Sekine, N. Ohtake, S. Nakata, K. Suzuki   +7 more
openaire   +1 more source

402 Somatic epigenetic mosaicism of FDFT1 underlies non-hereditary localized form of porokeratosis

Journal of Investigative Dermatology
S. Saito, Y. Saito, S. Sato, S. Aoki, H. Fujita, Y. Ito, N. Ono, T. Funakoshi, T. Kawai, H. Suzuki, T. Sasaki, K. Hata, K. Kataoka, K. Kosaki, M. Amagai, K. Nakabayashi, A. Kubo   +16 more
openaire   +1 more source

602 ASSOCIATION OF POLYMORPHIC MARKERS C3386A OF HMGCR GENE AND G(-198)A OF FDFT1 GENE WITH CORONARY ARTERY DISEASE

Atherosclerosis Supplements, 2011
A.N. Brovkin, K.A. Blagodatskikh, D.A. Zateyshchikov, L.O. Minushkina, A.G. Nikitin, V.V. Nosikov   +5 more
openaire   +1 more source

Mapping of the GATA4, NEIL2, FDFT1 genes and CTSB‐associated microsatellites to the centromeric region of BTA8

Animal Genetics, 2004
A, Plis-Finarov, H, Hudson, B, Roe, M, Ron, E, Seroussi   +4 more
openaire   +2 more sources

Dysregulation of FDFT1 expression in Parkinson's Disease.

openaire   +1 more source

FDFT1 Reduces Stemness and Autocrine/Juxtacrine Signaling in FOLFOX-resistant Colon Cancer Cells

JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
openaire   +1 more source