Results 91 to 100 of about 480,216 (163)

Intra-amygdala injections of neuropeptide S block fear-potentiated startle

, 2010
Injections of neuropeptide S (NPS) into the lateral ventricle induce a strong hyperactivity. Since most behavioral paradigms are dependent of spontaneous locomotor activity, this makes it difficult to interpret the role of NPS in such paradigms.
Fendt, Markus, Buerki, Hugo, Imobersteg, Stefan, Mcallister, Kevin, Sailer, Andreas, Stefan Imobersteg, Hugo Bürki, Markus Fendt, Kevin H. McAllister, Andreas W. Sailer   +9 more
core   +1 more source

Pharmacology of human experimental anxiety

Brazilian Journal of Medical and Biological Research, 2003
This review covers the effect of drugs affecting anxiety using four psychological procedures for inducing experimental anxiety applied to healthy volunteers and patients with anxiety disorders.
F.G. Graeff, A. Parente, C.M. Del-Ben, F.S. Guimarães   +3 more
doaj   +1 more source

Repeated elicitation of the acoustic startle reflex leads to sensitisation in subsequent avoidance behaviour and induces fear conditioning [PDF]

, 2011
Background: Autonomous reflexes enable animals to respond quickly to potential threats, prevent injury and mediate fight or flight responses. Intense acoustic stimuli with sudden onsets elicit a startle reflex while stimuli of similar intensity but with ...
Vincent M Janik, Götz Thomas, Gotz, Thomas, Janik Vincent M, Janik, Vincent, Thomas Götz, Gotz, Thomas; id_orcid, Janik, Vincent; id_orcid   +7 more
core   +1 more source

Modeling startle eyeblink electromyogram to assess fear learning [PDF]

, 2017
Pavlovian fear conditioning is widely used as a laboratory model of associative learning in human and nonhuman species. In this model, an organism is trained to predict an aversive unconditioned stimulus from initially neutral events (conditioned stimuli,
Bach, DR, Khemka, S, Tzovara, A, Gerster, S, Quednow, BB   +4 more
core  

Transfer of Conditioned Fear-potentiated Startle across Equivalence Classes. An Exploratory Study

, 2016
Research on fear conditioning is key to understanding the genesis and maintenance of anxiety disorders. A still scarce but growing evidence shows that fear-conditioned arousal reactions may transfer amongst physically dissimilar but symbolically related (
López Medina, Miguel Ángel, Hernández López, Mónica, Rodríguez Valverde, Miguel   +2 more
core  

Pharmacological analysis of fear-potentiated startle.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 1994
1. The potentiated startle paradigm measures conditioned fear by an increase in the amplitude of a simple reflex (the acoustic startle reflex) in the presence of a cue previously paired with shock. This paradigm offers a number of advantages as an alternative to most animal tests of fear or anxiety because it involves no operant and is reflected by an ...
openaire   +1 more source

Acoustic startle and fear‐potentiated startle in rats selectively bred for fast and slow kindling rates: relation to monoamine activity

, 2000
The acoustic startle response, prepulse inhibition, fear-potentiated startle and monoamine activity induced by either, a novel stimulus or a cue previously paired with foot-shock (fear-conditioning), were assessed in rats selectively bred for differences
Merali, Zul, Shawn Hayley, Hayley, Shawn, Hymie Anisman, Anisman, Hymie, Owen Kelly, Borowski, Thomas, Zul Merali, McIntyre, Dan C, Thomas Borowski, Dan C. McIntyre, Owen, Kelly   +11 more
core   +1 more source

Fear conditioning following unilateral temporal lobectomy : dissociation of conditioned startle potentiation and autonomic learning

, 2005
The present study investigated fear-potentiated startle and autonomic learning in brain-lesioned patients in a classical fear-conditioning paradigm. Startle blink and skin conductance responses of 30 patients who underwent unilateral temporal lobectomy ...
Schroeder, Henry W. S., Runge, Uwe, Kessler, Christof, Weike, Almut I., Hamm, Alfons, Schupp, Harald T.   +5 more
core   +1 more source

Associations between PACAP levels and psychophysiological indicators of fear and arousal in adults with posttraumatic stress symptoms

Journal of Mood and Anxiety Disorders
Posttraumatic stress disorder (PTSD) is associated with heightened fear responding and decreased fear regulation, as demonstrated with psychophysiological measures (e.g., autonomic function) and circulating biomarkers of stress, such as pituitary ...
Antonia V. Seligowski, Kevin J. Clancy, Eylül Akman, Michael Lewis, Victor May, Caitlin Ravichandran, Sydney A. Jobson, Daniel E. Bradford, Sayamwong E. Hammack, William A. Carlezon, Jr., Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso   +12 more
doaj   +1 more source

Involvement of subcortical and cortical afferents to the lateral nucleus of the amygdala in fear conditioning measured with fear- potentiated startle in rats trained concurrently with auditory and visual conditioned stimuli

, 1995
The goal of this work was to test the involvement, in fear conditioning, of afferents to the lateral nucleus of the amygdala originating from the auditory thalamus, auditory cortex, and perirhinal area.
M Davis, S Campeau
core   +1 more source