Generalization gradients for fear and disgust in human associative learning
Scientific Reports, 2021 Previous research indicates that excessive fear is a critical feature in anxiety disorders; however, recent studies suggest that disgust may also contribute to the etiology and maintenance of some anxiety disorders.
Jinxia Wang +4 more
doaj +1 more source
Impaired contextual modulation of memories in PTSD: an fMRI and psychophysiological study of extinction retention and fear renewal [PDF]
, 2014 Post-traumatic stress disorder (PTSD) patients display pervasive fear memories, expressed indiscriminately. Proposed mechanisms include enhanced fear learning and impaired extinction or extinction recall. Documented extinction recall deficits and failure
Abelson, James L +6 more
core +1 more source
Extinction in Human Fear Conditioning [PDF]
Biological Psychiatry, 2006 Although most extinction research is conducted in animal laboratories, the study of extinction learning in human fear conditioning has gained increasing attention over the last decade. The most important findings from human fear extinction are reviewed in this article.
Hermans, Dirk +3 more
openaire +3 more sources
Avoidant symptoms in PTSD predict fear circuit activation during multimodal fear extinction [PDF]
, 2013 Convergent evidence suggests that individuals with posttraumatic stress disorder (PTSD) exhibit exaggerated avoidance behaviors as well as abnormalities in Pavlonian fear conditioning.
Israel eLiberzon +4 more
core +2 more sources
Functional imaging of stimulus convergence in amygdalar neurons during Pavlovian fear conditioning. [PDF]
PLoS ONE, 2009 BACKGROUND:Associative conditioning is a ubiquitous form of learning throughout the animal kingdom and fear conditioning is one of the most widely researched models for studying its neurobiological basis.
Sabiha K Barot +3 more
doaj +1 more source
Hippocampal structural plasticity accompanies the resulting contextual fear memory following stress and fear conditioning [PDF]
, 2013 The present research investigated the resulting contextual fear memory and structural plasticity changes in the dorsal hippocampus (DH) following stress and fear conditioning. This combination enhanced fear retention and increased the number of total and
Calfa, Gaston Diego +2 more
core +1 more source
Frontiers in Behavioral Neuroscience, 2009 Early life trauma alters later life emotions, including fear. To better understand mediating mechanisms, we subjected pups to either predictable or unpredictable trauma, in the form of paired or unpaired odor-0.5mA shock conditioning which, during a ...
Stephanie Moriceau +11 more
doaj +1 more source
Maintenance of aversive memories shown by fear extinction-impaired phenotypes is associated with increased activity in the amygdaloid-prefrontal circuit [PDF]
, 2016 Although aversive memory has been mainly addressed by analysing the changes occurring in average populations, the study of neuronal mechanisms of outliers allows understanding the involvement of individual differences in fear conditioning and extinction.
Caioli, Silvia +5 more
core +1 more source
Dopamine D1-like receptor signalling in the hippocampus and amygdala modulates the acquisition of contextual fear conditioning [PDF]
, 2015 RATIONALE: Dopamine D1-like receptor signalling is involved in contextual fear conditioning, but the brain regions involved and its role in other contextual fear memory processes remain unclear.
Bast, Tobias +8 more
core +4 more sources
Frontiers in Neural Circuits, 2021 Post-traumatic stress disorder (PTSD) is a debilitating and chronic fear-based disorder. Pavlovian fear conditioning protocols have long been utilised to manipulate and study these fear-based disorders.
Nicholas Chaaya +21 more
doaj +1 more source