Results 101 to 110 of about 9,527 (221)

Febuxostat efficiently reduces the progression of chronic kidney disease in asymptomatic hyperuricemia: an interventional study

The Egyptian Journal of Internal Medicine
Background Therapeutic approaches for addressing asymptomatic chronic kidney disease (CKD) with renal impairment requires careful consideration, as there is a lack of substantial evidence endorsing specific medications.
Showkat Azad, Pradip Kumar Dutta, Md Nurul Huda, Mohammad Abdul Kader, Biplob Kumar Barua, Mohammad Shawkat Ali, Maria Mehjabin Akhi, Mishu Rahman, Jannatul Efte Ekra, Md. Sujan Islam, Sadia Afrin, Mohammed Mehadi Hassan Chowdhury, Subodh Kumar Sarkar, Ashekul Islam   +13 more
doaj   +1 more source

Comparative efficacy and safety of febuxostat and allopurinol in chronic kidney disease stage 3–5 patients with asymptomatic hyperuricemia: a network meta-analysis

Renal Failure
Objective This study evaluates and compares the effectiveness and safety of febuxostat and allopurinol in chronic kidney disease (CKD) stages 3–5 patients with asymptomatic hyperuricemia using a network meta-analysis.Methods A systematic review and ...
Jiaojiao Chen, Yanyun Zhang, Yinglin Wang, Lu Chen   +3 more
doaj   +1 more source

Febuxostat improves outcome in a rat model of cancer cachexia [PDF]

, 2015
Masaaki Konishi, Loes Pelgrim, Anika Tschirner, Anna Baumgarten, Stephan von Haehling, Sandra Palus, Wolfram Doehner, Stefan D. Anker, Jochen Springer   +8 more
openalex   +1 more source

Renoprotective Effect of Febuxostat Compared with Allopurinol in Hyperuricemic Chronic Kidney Disease Patients Stage 3 and 4 [PDF]

, 2022
Heba Elshair, Yasser Nienaa, Rana Koreen, Noha Elkholy   +3 more
openalex   +1 more source

Neue Erkenntnisse zur Pathophysiologie und Therapie der Gicht [PDF]

, 2018
Zusammenfassung: Gicht wird durch die Ablagerung von Mononatriumurat- (MNU-)Kristallen im Gewebe verursacht, durch die eine lokale Entzündungsreaktion ausgelöst wird. Bei älteren Menschen ist sie die häufigste entzündliche Gelenkerkrankung.
So, A.
core  

POS0282 UPDATE ON COMPARATIVE CARDIOVASCULAR SAFETY OF FEBUXOSTAT VERSUS ALLOPURINOL AMONG PATIENTS WITH GOUT [PDF]

, 2022
Anna Shin, Y. J. Ha, Y. J. Lee, E. B. Lee, E. H. Kang   +4 more
openalex   +1 more source

Efficacy and safety of febuxostat in elderly female patients

Clinical Interventions in Aging, 2014
Tomohiro Mizuno,1,2 Takahiro Hayashi,3 Sayo Hikosaka,1 Yuka Shimabukuro,1 Maho Murase,1 Kazuo Takahashi,2 Hiroki Hayashi,2 Yukio Yuzawa,2 Tadashi Nagamatsu,1 Shigeki Yamada3 1Department of Analytical Pharmacology, Graduate School of Pharmacy, Meijo ...
Mizuno T, Hayashi T, Hikosaka S, Shimabukuro Y, Murase M, Takahashi K, Hayashi H, Yuzawa Y, Nagamatsu T, Yamada S   +9 more
doaj  

Xanthine oxidoreductase inhibition ameliorates high glucose-induced glomerular endothelial injury by activating AMPK through the purine salvage pathway

Scientific Reports
Xanthine oxidoreductase (XOR) contributes to reactive oxygen species production. We investigated the cytoprotective mechanisms of XOR inhibition against high glucose (HG)-induced glomerular endothelial injury, which involves activation of the AMP ...
Keum-Jin Yang, Hwajin Park, Yoon-Kyung Chang, Cheol Whee Park, Suk Young Kim, Yu Ah Hong   +5 more
doaj   +1 more source

Antioxidant action of xanthine oxidase inhibitor febuxostat protects the liver and blood vasculature in SHRSP5/Dmcr rats [PDF]

, 2023
M. Kakimoto, Moe Fujii, Ikumi Sato, Koki Honma, Hinako Nakayama, Sora Kirihara, Taketo Fukuoka, Shang Ran, Satoshi Hirohata, Kazuya Kitamori, Shusei Yamamoto, Shogo Watanabe   +11 more
openalex   +1 more source

Cardiovascular safety of febuxostat versus allopurinol among the Asian patients with or without gout: A systematic review and meta‐analysis

Clinical and Translational Science
The cardiovascular (CV) safety of febuxostat compared to allopurinol for the treatment of hyperuricemia among Asian patients is uncertain. In this study, we conducted a systematic review and meta‐analysis to compare the CV safety profiles of febuxostat ...
Jian‐hao Deng, Peng‐hui Lai, Li‐shan Xie, Shu‐sheng Qiu, De‐sheng Qiu, Jia‐xing Zhang   +5 more
doaj   +1 more source