Results 101 to 110 of about 9,243 (198)

The Pharmacodynamics, Pharmacokinetics, and Safety of Arhalofenate in Combination with Febuxostat When Treating Hyperuricemia Associated with Gout [PDF]

open access: bronze, 2016
Alexandra Steinberg   +5 more
openalex   +1 more source

Sintesis, penilaian biologi dan kajian dok sebatian auron ke atas enzim xantin oksidase [PDF]

open access: yes, 2018
Perencatan aktiviti xantin oksidase (XO) merupakan satu pendekatan terapeutik yang berkesan dalam rawatan penyakit seperti gout dan hiperurikemia. Selain itu, penggunaan perencat XO juga dapat diluaskan kepada rawatan kecederaan contohnya reperfusi ...
Ang, Serene   +4 more
core  

Patients Prescribed Anakinra for Acute Gout Have Baseline Increased Burden of Hyperuricemia, Tophi, and Comorbidities, and Ultimate All-Cause Mortality. [PDF]

open access: yes, 2019
Objective:The interleukin-1 (IL-1) receptor antagonist anakinra is an effective, off-label option in acute gout flares, when conventional therapy options are narrowed.
Pedersen, Brian   +2 more
core  

Febuxostat efficiently reduces the progression of chronic kidney disease in asymptomatic hyperuricemia: an interventional study

open access: yesThe Egyptian Journal of Internal Medicine
Background Therapeutic approaches for addressing asymptomatic chronic kidney disease (CKD) with renal impairment requires careful consideration, as there is a lack of substantial evidence endorsing specific medications.
Showkat Azad   +13 more
doaj   +1 more source

Neue Erkenntnisse zur Pathophysiologie und Therapie der Gicht [PDF]

open access: yes, 2018
Zusammenfassung: Gicht wird durch die Ablagerung von Mononatriumurat- (MNU-)Kristallen im Gewebe verursacht, durch die eine lokale Entzündungsreaktion ausgelöst wird. Bei älteren Menschen ist sie die häufigste entzündliche Gelenkerkrankung.
So, A.
core  

Antioxidant action of xanthine oxidase inhibitor febuxostat protects the liver and blood vasculature in SHRSP5/Dmcr rats [PDF]

open access: gold, 2023
M. Kakimoto   +11 more
openalex   +1 more source

Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice [PDF]

open access: gold, 2019
Yu Mizuno   +15 more
openalex   +1 more source

Cardiovascular safety of febuxostat versus allopurinol among the Asian patients with or without gout: A systematic review and meta‐analysis

open access: yesClinical and Translational Science
The cardiovascular (CV) safety of febuxostat compared to allopurinol for the treatment of hyperuricemia among Asian patients is uncertain. In this study, we conducted a systematic review and meta‐analysis to compare the CV safety profiles of febuxostat ...
Jian‐hao Deng   +5 more
doaj   +1 more source

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