Results 81 to 90 of about 9,527 (221)
Uric Acid, Arterial Stiffness and Blood Pressure: A Population‐Based Cohort Study
ABSTRACT Background and Aim Serum uric acid (SUA) has long been linked to elevated blood pressure (BP) in observational clinical studies. Nonetheless, data regarding the correlation between SUA and BP are controversial in randomized controlled trials and mendelian randomization research.
Lijun Li +5 more
wiley +1 more source
Gout – a treatable condition [PDF]
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked FilesÞvagsýrugigt er liðbólgusjúkdómur sem í flestum tilfellum er læknanlegur en ...
Björn Guðbjörnsson +3 more
core +1 more source
Fatal Tumor Lysis Syndrome Induced by Pembrolizumab in Advanced Renal Pelvis Cancer
ABSTRACT Introduction Tumor lysis syndrome (TLS) arises from the rapid breakdown of tumor cells during oncological treatment. Although TLS is rarely observed in solid tumors, few studies have documented instances of TLS associated with pembrolizumab. This report presents a case involving pembrolizumab‐induced TLS.
Takashi Asakura +3 more
wiley +1 more source
Особенности лечения подагры у пациентов пожилого возраста [PDF]
Представлен обзор литературы по проблеме лечения подагры у пациентов пожилого ...
Андрианова, М. А. +3 more
core +2 more sources
Increased Adenine Nucleotide Degradation in Skeletal Muscle Atrophy [PDF]
Adenine nucleotides (AdNs: ATP, ADP, AMP) are essential biological compounds that facilitate many necessary cellular processes by providing chemical energy, mediating intracellular signaling, and regulating protein metabolism and solubilization.
Brault, Jeffrey J. +2 more
core +1 more source
Three metabolites, pyroglutamylglycine (pyroGluGly), phenylalanine (Phe), and phenylalanyltryptophan (PheTrp), were identified as candidate DILI biomarkers. The serum concentrations of pyroGluGly, Phe, and PheTrp demonstrated a high differentiating ability in patients with mixed and cholestatic DILI compared with those in patients who recovered from ...
Kosuke Saito +22 more
wiley +1 more source
Relationship Between Characteristics of Medications and Drug-Induced Liver Disease Phenotype and Outcome [PDF]
Background & Aims: It is not known if specific characteristics of medication are associated with type of drug-induced liver injury (DILI) or outcome.
Chalasani, Naga +8 more
core +1 more source
The last defence? Surgical aspects of gouty arthritis of hand and wrist [PDF]
OBJECTIVE: To review the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of gouty arthritis of the hand and wrist, with a focus on the surgical aspects. DATA SOURCES AND EXTRACTION: Electronic databases including MEDLINE,
Fung, BKK, Tang, CKY
core
Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy [PDF]
INTRODUCTION: Two replicate randomized, placebo-controlled six-month trials (RCTs) and an open-label treatment extension (OLE) comprised the pegloticase development program in patients with gout refractory to conventional therapy.
Baraf, Herbert SB +9 more
core +2 more sources
K, Wittköpper, J, Emons, A, El-Armouche
openaire +5 more sources

