Results 61 to 70 of about 180,670 (278)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Methodological considerations in the analysis of fecal glucocorticoid metabolites in tufted capuchins (Cebus apella) [PDF]

, 2013
Analysis of fecal glucocorticoid (GC) metabolites has recently become the standard method to monitor adrenocortical activity in primates noninvasively. However, given variation in the production, metabolism, and excretion of GCs across species and even ...
Wheeler, Brandon C., Michael Heistermann, Tiddi, Barbara, Brandon C. Wheeler, Heistermann, M., Tiddi, B., Kalbitzer, U., Visalberghi, E., Wheeler, Brandon C, Visalberghi, Elisabetta, Heistermann, Michael, Wheeler, B., Elisabetta Visalberghi, Urs Kalbitzer, Kalbitzer, Urs, Barbara Tiddi   +15 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Gut microbiome predictors of Escherichia coli sequence type 131 colonization and lossResearch in context

EBioMedicine
Summary: Background: Escherichia coli sequence type 131 (ST131), specifically its fluoroquinolone-resistant H30R clade (ST131-H30R), is a global multidrug-resistant pathogen.
Daniel E. Park, Maliha Aziz, Benjamin J. Koch, Kelsey Roach, Connie Clabots, James R. Johnson, Lance B. Price, Cindy M. Liu   +7 more
doaj   +1 more source

Prevalence and household risk factors for fecal carriage of ESBL-producing, sequence type 131, and extraintestinal pathogenic Escherichia coli among children in southern Taiwan

Journal of Microbiology, Immunology and Infection, 2022
Background: The rapidly increasing prevalence of antimicrobial-resistant Escherichia coli (E. coli) is a global concern. This study determined the prevalence and risk factors for the fecal carriage of drug-resistant E. coli and extraintestinal pathogenic
Ming-Fang Cheng, Pei-Yu Ho, Jiun-Ling Wang, Fan-Chen Tseng, Jenn-Tzong Chang, I-Fei Huang, Chih-Hsin Hung   +6 more
doaj   +1 more source

A mathematical model of serotype replacement in pneumococcal carriage following vaccination. [PDF]

, 2013
A number of childhood vaccination programmes have recently introduced vaccination against Streptococcus pneumoniae, the pneumococcus, a major cause of pneumonia and meningitis.
Bottomley, Christian, Roca, Anna, Hill, Philip C, Isham, Valerie, Greenwood, Brian   +4 more
core   +1 more source

Fecal Carriage of Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococcus in Healthy Children [PDF]

Antimicrobial Agents and Chemotherapy, 2014
Methicillin resistant Staphylococcus aureus (MRSA) and vancomycin resistant enterococci (VRE) present major challenges (1-4).…
Emily A, Gurnee, I Malick, Ndao, Jessica E, McGhee, Barbara B, Warner, Phillip I, Tarr, Stephanie A, Fritz, Carey-Ann D, Burnham   +6 more
openaire   +2 more sources

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Fecal Carriage of Carbapenem Resistant Enterobacterales and Associated Factors Among Admitted Patients in Saint Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia

Infection and Drug Resistance, 2023
Yonas Mekonnen,1,2 Semaria Solomon,1 Alganesh Gebreyohanns,1 Dejenie Shiferaw Teklu,2 Zeleke Ayenew,2 Amete Mihret,2 Zelalem Tazu Bonger3 1Department of Medical Microbiology, Immunology and Parasitology, Saint Paul’s Hospital Millennium Medical College ...
Mekonnen Y, Solomon S, Gebreyohanns A, Teklu DS, Ayenew Z, Mihret A, Bonger ZT   +6 more
doaj  

Multi-serotype pneumococcal nasopharyngeal carriage prevalence in vaccine naïve Nepalese children, assessed using molecular serotyping. [PDF]

, 2015
Invasive pneumococcal disease is one of the major causes of death in young children in resource poor countries. Nasopharyngeal carriage studies provide insight into the local prevalence of circulating pneumococcal serotypes.
Gurung, M, Kandasamy, Rama, Neelam Adhikari, David R Murdoch, Katherine A Gould, Murdoch, DR, Thapa, A, Adhikari, N, Hinds, Jason, Shrestha, S, Gould, Katherine A., Anushil Thapa, Kandasamy, R ; https://orcid.org/, Waldron, Denise E., Stephen Thorson, Rama Kandasamy, Waldron, DE, Gould, KA, Ndimah, S, Thorson, Stephen, Kelly, Dominic F., Shrijana Shrestha, Thorson, S, Dominic F Kelly, Meeru Gurung, Thapa, Anushil, Andrew J Pollard, Murdoch, David R., Ndimah, Susan, Shrestha, Shrijana, Denise E Waldron, Hinds, J, Pollard, Andrew J., Kandasamy, R, Adhikari, Neelam, Jason Hinds, Kelly, DF, Gurung, Meeru, Pollard, AJ, Pollard, Andrew, Susan Ndimah   +40 more
core   +2 more sources