Results 21 to 30 of about 103,350 (330)
Dissecting cell death pathways in fed-batch bioreactors. [PDF]
Biotechnol J, 2023 AbstractChinese hamster ovary (CHO) cells are widely used for production of biologics including therapeutic monoclonal antibodies. Cell death in CHO cells is a significant factor in biopharmaceutical production, impacting both product yield and quality.
Mentlak DA +12 more
europepmc +4 more sources
Egyptian Journal of Biological Pest Control, 2020 The effect of batch and fed-batch fermentation on the cultivation performance of Bacillus thuringiensis was investigated using a 5-l stirred tank bioreactor.
Mohamed Mazmira Mohd Masri +1 more
doaj +1 more source
Comprehensive clone screening and evaluation of fed-batch strategies in a microbioreactor and lab scale stirred tank bioreactor system : application on Pichia pastoris producing Rhizopus oryzae lipase [PDF]
, 2014 Background: In Pichia pastoris bioprocess engineering, classic approaches for clone selection and bioprocess optimization at small/micro scale using the promoter of the alcohol oxidase 1 gene (PAOX1), induced by methanol, present low reproducibility ...
Adelantado Vallvé, Núria +7 more
core +4 more sources
Optimization of fed-batch fermentation processes using the Backtracking Search Algorithm [PDF]
, 2017 Fed-batch fermentation has gained attention in recent years due to its beneficial impact in the economy and productivity of bioprocesses. However, the complexity of these processes requires an expert system that involves swarm intelligence-based ...
Chuah, Joon Huang +3 more
core +2 more sources
Minimal time control of fed-batch processes with growth functions having several maxima [PDF]
, 2010 We address the issue of minimal time optimal control of fedbatch reactor in presence of complex non monotonic kinetics, that can be typically characterized by the combination of two Haldane models. The optimal synthesis may present several singular arcs.
Dochain, Denis, Rapaport, Alain
core +7 more sources
Influence of different SSF conditions on ethanol production from corn stover at high solids loadings [PDF]
, 2015 In this study, three different kinds of simultaneous saccharification and fermentation (SSF) of washed pretreated corn stover with water-insoluble solids (WIS) content of 20% were investigated to find which one resulted in highest ethanol yield at high ...
Bondesson, Pia-Maria +3 more
core +1 more source
Journal of Biological Engineering, 2019 Background Fed-batch conditions are advantageous for industrial cultivations as they avoid unfavorable phenomena appearing in batch cultivations. Those are for example the formation of overflow metabolites, catabolite repression, oxygen limitation or ...
T. Keil +4 more
doaj +1 more source
Levan Production in Shake Flask and Fermenter Influence of Feeding Strategy on Levan Yield and Molecular Weight Distribution [PDF]
E3S Web of Conferences, 2023 Effect of feeding strategy on levan production was studied in a shake flask and a 5 L lab scale fermenter. In a shake flask, levan specific substrate yield (YP/S) increased from 0.35 g levan/g sucrose to 0.48 g levan/g sucrose with repeated batch feeding.
Veerapandian Bhuvaneshwari +5 more
doaj +1 more source
Journal of Biological Engineering, 2020 Background Small-scale cultivation vessels, which allow fed-batch operation mode, become more and more important for fast and reliable early process development.
Timm Keil +3 more
doaj +1 more source
Fisheries and Aquatic Sciences, 2018 As a process for commercial application, production of reducing sugar, antioxidant, and DNA protective compounds from shrimp-shell powder was investigated in a fed-batch biodegradation using Bacillus cereus EW5.
Harun Ar Rashid +2 more
doaj +1 more source