Results 191 to 200 of about 28,581 (261)

Regenerative perfusion bioreactor for biologics production with lower COGs

open access: yesBiotechnology Progress, EarlyView.
Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne   +5 more
wiley   +1 more source

Integrating real-time OUR monitoring with adaptive feeding for enhanced antibody production. [PDF]

open access: yesBioresour Bioprocess
Zhang XR   +6 more
europepmc   +1 more source

Whole-genome DNA methylation analysis of Chinese hamster ovary cells undergoing media adaptation. [PDF]

open access: yesFront Bioeng Biotechnol
Roy S   +7 more
europepmc   +1 more source

Methanol feeding strategies for high-yield production of a collagen-based protein in Komagataella phaffii. [PDF]

open access: yesAppl Microbiol Biotechnol
Ebbecke JP   +5 more
europepmc   +1 more source
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Fed-batch culture technology

Biotechnology Advances, 1986
The use of fed-batch procedures offers distinct advantages over other modes of operation of bioreactors, and is a widely researched technique. These advantages are discussed; some uses of fed-batch procedures and the associated methods of modelling and control are reviewed.
B J, Minihane, D E, Brown
openaire   +2 more sources

An analysis of extended and exponentially‐fed‐batch cultures

Biotechnology and Bioengineering, 1977
AbstractUnder certain conditions it is shown that an extended culture is equivalent to an exponentially‐fed‐batch culture, that an exponentially‐fed‐batch culture (and an extended culture) can be maintained at a steady state and that an exponentially‐fed‐batch culture may be mimicked by a continuous‐flow culture with a constant dilution rate ...
H C, Lim, B J, Chen, C C, Creagan
openaire   +2 more sources

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