Results 261 to 270 of about 52,203 (302)

Glycerol production by fermentation: A fed‐batch approach

Biotechnology and Bioengineering, 1987
In this investigation the bioconversion of glycerol from glucose was studied in a laboratory fermentor using an alkaline medium with a fed batch mode of carbon source addition yielding 30% glycerol concentration in the final broth. (Refs. 9).
P, Vijaikishore, N G, Karanth
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Optimization for a recombinantE. coli fed-batch fermentation

Applied Biochemistry and Biotechnology, 1995
The operating strategy that produces the maximum foreign protein expression for a fed-batch process is desired. This is achieved by using a feasible quadratic programming (FSQP) algorithm with a structured model that describes cell growth and product formation for recombinant E. coli.
Q, Chen, W E, Bentley, W A, Weigand
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Fed-batch versus batch fermentation

Bioprocess Engineering, 1994
This article concerns the comparison between batch and fed-batch fermentation based on productivity and including the analysis of the implications on product manufacturing cost.
openaire   +1 more source

Modeling for Control of Fed-Batch Fermenters

IFAC Proceedings Volumes, 2000
Abstract A simple method for controlling fed-batch fermenters is presented. Two linear models are derived for control design. The first one relates the input to the desired operating point. The second model describes the exponential cell growth as an unstable disturbance.
Sergio Valentinotti, Ulf Holmberg, Christopher Cannizzaro, Dominique Bonvin   +3 more
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Adaptive Control of Fed-Batch Fermentation Processes

IFAC Proceedings Volumes, 1988
Abstract In this paper, it is shown how a simple adaptive control algorithm can contribute to optimize the yield of fermentation processes operated in fed-batch. The proposed algorithm does not require any prior analytical expression for the fermentation parameters (like the specific growth rate or the specific production rate).
D. Dochain, G. Bastin
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Microbial growth kinetics of fed-batch fermentations

Applied Microbiology and Biotechnology, 1988
Fed-batch fermenters are generally operated with the addition of small doses of nutrients, therefore the volume of the fermentation broth increases with time. Batch fermenters generally contain and almost constant volume of broth and a logistic equation has been commonly employed to simulate microbial growth in them.
F. �zadali, M. �zilgen
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Optimal nonsingular control of fed‐batch fermentation

Biotechnology and Bioengineering, 1991
AbstractPresented is a new simple method for multidimensional optimization of fed‐batch fermentations based on the use of the orthogonal collocation technique. Considered is the problem of determination of optimal programs for fermentor temperature, substrate concentration in feed, feeding profile, and process duration.
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Sauerstoff-fed-batch: Prozeßführung — Fermenter — Meßgeräte

1981
Diese Arbeit befast sich mit Prozesfuhrungsstrategien fur die Bildung von Sekundarmetabohten unter Sauerstofflimitierung. Ausgehend von einer Kinetik der spezifischen Produktbildungsrate als Funktion der spezifischen Sauerstoffaufnahmerate wird der Sauerstoff-fed-batch in seinen Modifikationen definiert und erlautert.
I. Adler, J. Lehmann
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Parameter Adaptive Control of the Fed-Batch Penicillin Fermentation

IFAC Proceedings Volumes, 1985
Abstract This paper describes a study to investigate the application of parameter adaptive control to mould growth in a fed-batch fermentation for penicillin production. Two models for the penicillin fermentation are described: a new mechanistic model is outlined and compared with a model based upon the work of Bajpai with an extension to include ...
G.A. Montague, A.J. Morris, A.R. Wright, M. Aynsley, A. Ward   +4 more
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Simple nonsingular control approach to fed‐batch fermentation optimization

Biotechnology and Bioengineering, 1989
AbstractDetermination of the optimal feed rate for fed‐batch fermentation is normally a problem in singular control with a state inequality constraint and as such is, in general, difficult to solve, especially for those described by a large number of dynamic mass balance equations.
J M, Modak, H C, Lim
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