Results 101 to 110 of about 87,565 (266)

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

British Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr, Christiane Dings, Omar Zaher, Frederike Nordmeier, Nadja Walle, Matthias W. Laschke, Michael D. Menger, Peter H. Schmidt, Markus R. Meyer, Thorsten Lehr, Nadine Schaefer   +10 more
wiley   +1 more source

Comparision of Caudal Ropivacaine, Ropivacaine Plus Ketamine and Ropivacaine Plus Fentanyl Administration for Postoperative Analgesia in Children

, 2013
Jeevan Singh, Dikshya Hamal, Avish Karmacharya   +2 more
openalex   +2 more sources

Developing a Co‐Designed Strategy to Improve Labor Monitoring and Management in India Using the World Health Organization Labour Care Guide: A Mixed‐Methods Formative Study

Birth, EarlyView.
ABSTRACT Introduction Nearly half of all perinatal deaths occur during the intrapartum period due to inadequate labor monitoring and intervention. The partograph, a paper‐based labor monitoring tool, can assist providers in recognizing and acting on early signs of fetal–maternal distress if used effectively. In 2020, the World Health Organization (WHO)
Elizabeth Armari, Sunil S. Vernekar, Yeshita Pujar, Veronica Pingray, Fernando Althabe, Luz Gibbons, Mabel Berrueta, Alvaro Ciganda, Rocio Rodriguez, Jayashree Ashok Kumar, Shruti Bhavi Patil, Aravind Karinagannanavar, Raveendra R. Anteen, Pavithra M. R., Savitri Bendigeri, Shukla Shetty, B. Latha, Megha H. M., Suman S. Gaddi, Shaila Chikkagowdra, Bellara Raghavendra, Caroline S. E. Homer, Manjunath Somannavar, Shivaprasad S. Goudar, Joshua P. Vogel   +24 more
wiley   +1 more source

Strategies used to reduce harms associated with fentanyl exposure among rural people who use drugs: multi-site qualitative findings from the rural opioid initiative

Harm Reduction Journal
Aim Illicitly manufactured fentanyl and its analogs are the primary drivers of opioid overdose deaths in the United States (U.S.). People who use drugs may be exposed to fentanyl or its analogs intentionally or unintentionally.
Suzan M. Walters, Robin Baker, David Frank, Monica Fadanelli, Abby E. Rudolph, William Zule, Rob J. Fredericksen, Rebecca Bolinski, Adams L. Sibley, Vivian F. Go, Lawrence J. Ouellet, Mai T. Pho, David W. Seal, Judith Feinberg, Gordon Smith, April M. Young, Thomas J. Stopka   +16 more
doaj   +1 more source

Fentanyl and fentanyl plus lidocaine on attenuation of haemodynamic stress response to laryngoscopy: a comparative study in controlled hypertensive patients posted for laparoscopic cholecystectomy

, 2015
Basant Kumar, Khagaswar Raut, Sidharth Sraban Routray   +2 more
openalex   +2 more sources

Leveraging the ADAM10 prodomain for selective inhibition to enhance recovery after myocardial infarction

British Journal of Pharmacology, EarlyView.
Background and Purpose Inflammation plays a crucial role in the development and progression of numerous acute and chronic diseases such as myocardial infarction (MI) and heart failure. Targeting ADAM proteases, particularly ADAM10, holds promise for fine‐tuning inflammatory responses.
Erik Klapproth, Johanna Marks, Patrick Diaba‐Nuhoho, Sören Grell, Paul Leubauer, Susanne Kämmerer, Johannes R. Soltwedel, Fred Rasmussen, Felix Mejia, Marcia L. Moss, Christopher Prince, Peter Mirtschink, Ben Wielockx, Paul Saftig, Michael Wagner, Kristina Lorenz, Ali El‐Armouche   +16 more
wiley   +1 more source

Comparison of the Effect of Remifentanil Plus Atropine with Fentanyl and Remifentanil Alone on Preterm Infants’ Vital Signs in Non-emergency Intratracheal Intubation

, 2022
Mirhadi Mussavi, Morteza Ghojazadeh, Samayeh dadakhani   +2 more
openalex   +2 more sources

Troriluzole attenuates opioid intake, reinforcing efficacy, seeking behaviours, physical dependence and antinociceptive tolerance in rats

British Journal of Pharmacology, EarlyView.
Background and Purpose Riluzole, approved for amyotrophic lateral sclerosis (ALS), has a glutamate‐modulating profile favourable for mitigating opioid addiction. It reduces neuronal glutamate release and enhances glutamate reuptake, offering advantages over agents that only increase glutamate reuptake.
Ewa Galaj, Saadet Inan, Guo‐Hua Bi, Sonita Wiah, George Adamson, Allen B. Reitz, Zheng‐Xiong Xi, Scott M. Rawls   +7 more
wiley   +1 more source

Single-dose fentanyl sublingual spray for breakthrough cancer pain

Clinical Pharmacology: Advances and Applications, 2013
Donald R Taylor Comprehensive Pain Care PC, Marietta, GA, USA Abstract: Breakthrough cancer pain (BTCP) is defined as a transient exacerbation of pain that arises in patients with otherwise controlled persistent pain. BTCP typically has a rapid onset and
Taylor DR
doaj  

Impact of Three Safety Interventions Targeting Off-Label Use of Immediate-Release Fentanyl on Prescription Trends: Interrupted Time Series Analysis [PDF]

, 2022
Aníbal García‐Sempere, Isabel Hurtado, Salvador Peiró, Francisco Sanchez‐Saez, Clara L. Rodríguez‐Bernal, Magda Puig-Ferrer, Manuel Escolano, Gabriel Sanfélix‐Gimeno   +7 more
openalex   +1 more source