Results 11 to 20 of about 188,238 (387)

Intraoperative fentanyl in endoscopic procedures and their impact on PACU time and costs [PDF]

open access: yesPerioperative Medicine
Background Extended stays in the postanesthesia care unit (PACU) pose challenges in high-volume endoscopies. This study investigates the impact of intraoperative fentanyl use on PACU duration, postoperative pain, and financial implications in outpatient ...
Miho Akabane   +4 more
doaj   +2 more sources

Charting the Fourth Wave: Geographic, Temporal, Race/Ethnicity, and Demographic Trends in Polysubstance Fentanyl Overdose Deaths in the United States, 2010-2021

open access: yesmedRxiv, 2022
Aims: To characterize polysubstance death in the United States during the transition to the fourth wave of the overdose crisis. To characterize co-involved substances in fatal overdose involving synthetic opioids (mainly illicitly manufactured fentanyl ...
Joseph R. Friedman, Chelsea L. Shover
semanticscholar   +1 more source

Sex- and Dose-Dependent Differences in the Development of an Addiction-Like Phenotype Following Extended-Access Fentanyl Self-Administration

open access: yesFrontiers in Pharmacology, 2022
Opioid use disorder (OUD) is a major epidemic in the United States, and fentanyl is a major culprit. The National Institute on Drug Abuse has highlighted an urgent need for research on the risks and outcomes of OUD with fentanyl; a better understanding ...
E. B. Towers, Ben Setaro, W. J. Lynch
semanticscholar   +1 more source

Increasing presence of xylazine in heroin and/or fentanyl deaths, Philadelphia, Pennsylvania, 2010–2019

open access: yesInjury Prevention, 2021
Reports from active drug users state that xylazine, the veterinary tranquilliser, has been increasing in the illicit drug supply in Philadelphia. To describe trends and characteristics of unintentional deaths from heroin and/or fentanyl overdose with ...
Jewell Johnson   +3 more
semanticscholar   +1 more source

Evidence of Buprenorphine-precipitated Withdrawal in Persons Who Use Fentanyl

open access: yesJournal of addiction medicine, 2021
Objectives Buprenorphine can precipitate withdrawal in opioid-dependent persons with recent fentanyl use. However, the prevalence of this phenomenon is not clinically established.
Neil B. Varshneya   +4 more
semanticscholar   +1 more source

How μ-opioid receptor recognizes fentanyl

open access: yesNature Communications, 2021
Roughly half of the drug overdose-related deaths in the United States are related to synthetic opioids represented by fentanyl which is a potent agonist of mu-opioid receptor (mOR).
Q. Vo   +3 more
semanticscholar   +1 more source

Suicide by Fentanyl [PDF]

open access: yesToxicology Letters, 2006
Suicide by FentanylFentanyl is a potent, short-acting narcotic analgesic widely used as surgical anaesthetic. This article presents a case in which fentanyl was self-injected by a 41-year old nurse, an employee at the hospital emergency department, who was found dead at home. She had no known history of drug and alcohol abuse.
Marija Definis-Gojanović   +1 more
openaire   +6 more sources

Mass Spectral Character of Fentanyl Analogues [PDF]

open access: yesFayixue Zazhi, 2019
Objective To provide the reference for the identification of unknown fentanyl analogues by studying the characteristic ions and main fragmentation pathways of fentanyl analogues in the modes of collision induced dissociation (CID) and electron ionization
YAN Jin, HUA Zhen-dong, JIA Wei, et al.
doaj   +1 more source

The anomalous pharmacology of fentanyl

open access: yesBritish Journal of Pharmacology, 2021
Fentanyl is a key therapeutic, used in anaesthesia and pain management. It is also increasingly used illicitly and is responsible for a large and growing number of opioid overdose deaths, especially in North America.
E. Kelly   +5 more
semanticscholar   +1 more source

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