Modeling Supports Combinatorial Effects Between Pharmacological and Non-Pharmacological Interventions to Prevent Opioid-Induced Cardiac Arrest. [PDF]
Clin Pharmacol TherFew studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Thrasher B +12 more
europepmc +2 more sources
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Safety of opioid patch initiation in Australian residential aged care [PDF]
, 2015 Explores opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Abstract Objective: To explore opioid use by aged care facility residents before and after initiation of transdermal opioid patches. Design:
Elizabeth Roughead +2 more
core +1 more source
Infectious Diseases and Therapy, 2023 Introduction An unsafe injection practice is one of the major contributors to new hepatitis C virus (HCV) infections; thus, people who inject drugs are a key population to prioritize to achieve HCV elimination.
Dwaipayan Mukherjee +8 more
doaj +1 more source
Assessing the 2004-2018 fentanyl misusing issues reported to an international range of adverse reporting systems [PDF]
, 2019 © 2019 Schifano, Chiappini, Corkery and Guirguis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania +3 more
core +4 more sources
Taiwanese Journal of Obstetrics & Gynecology, 2011 Objective: Pain affects many cancer patients in advancing stages, lowering the level of their quality of life. Morphine has long been the “gold standard” for the treatment of cancer pain; however, its side effects, particularly sedation and cognitive ...
Chiharu Kanamori +3 more
doaj +1 more source
Development of a New Method Based on Copper Sulfide Nanoparticles for the Determination of Fentanyl in Biological Samples [PDF]
ImmunoAnalysis, 2022 Background: Fentanyl is an opioid analgesic drug extensively used to alleviate pain with no consciousness loss. To address the fentanyl crisis from the criminal and medical perspectives,the development of a free drug determination methodology for this ...
Sedigheh Mohammadzadeh, Zahra Karimzadeh
doaj +1 more source
Research Progress on Machine Learning Assisted Non-Targeted Screening Strategy for Identification of Fentanyl Analogs [PDF]
Fayixue Zazhi, 2023 In recent years, the types and quantities of fentanyl analogs have increased rapidly. It has become a hotspot in the illicit drug control field of how to quickly identify novel fentanyl analogs and to shorten the blank regulatory period.
Yu-qi CAO, Yan SHI, Ping XIANG, Yin-long GUO
doaj +1 more source
Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) [PDF]
, 2018 The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
Adamek +196 more
core +1 more source