Results 11 to 20 of about 87,565 (266)

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Research Progress on Machine Learning Assisted Non-Targeted Screening Strategy for Identification of Fentanyl Analogs [PDF]

Fayixue Zazhi, 2023
In recent years, the types and quantities of fentanyl analogs have increased rapidly. It has become a hotspot in the illicit drug control field of how to quickly identify novel fentanyl analogs and to shorten the blank regulatory period.
Yu-qi CAO, Yan SHI, Ping XIANG, Yin-long GUO
doaj   +1 more source

Assessment of Drug–Drug Interaction Risk Between Intravenous Fentanyl and the Glecaprevir/Pibrentasvir Combination Regimen in Hepatitis C Patients Using Physiologically Based Pharmacokinetic Modeling and Simulations

Infectious Diseases and Therapy, 2023
Introduction An unsafe injection practice is one of the major contributors to new hepatitis C virus (HCV) infections; thus, people who inject drugs are a key population to prioritize to achieve HCV elimination.
Dwaipayan Mukherjee, Michelle Collins, Douglas E. Dylla, Jatinder Kaur, Dimitri Semizarov, Anthony Martinez, Brian Conway, Tipu Khan, Nael M. Mostafa   +8 more
doaj   +1 more source

Impact of Intrathecal Fentanyl on Hospital Outcomes for Patients Undergoing Primary Total Hip Arthroplasty With Neuraxial Anesthesia

Arthroplasty Today, 2021
Background: Intrathecal opioids have been used to reduce pain after total joint arthroplasty; however, the utility of these drugs is disputed. We examined the impact of eliminating intrathecal fentanyl on outcomes for patients undergoing direct anterior ...
McKayla Kelly, BS, Justin Turcotte, PhD, MBA, Jacob Aja, PA-C, James MacDonald, MD, Paul King, MD   +4 more
doaj   +1 more source

Development of a New Method Based on Copper Sulfide Nanoparticles for the Determination of Fentanyl in Biological Samples [PDF]

ImmunoAnalysis, 2022
Background: Fentanyl is an opioid analgesic drug extensively used to alleviate pain with no consciousness loss. To address the fentanyl crisis from the criminal and medical perspectives,the development of a free drug determination methodology for this ...
Sedigheh Mohammadzadeh, Zahra Karimzadeh
doaj   +1 more source

“It wasn’t here, and now it is. It’s everywhere": fentanyl’s rising presence in Oregon’s drug supply

Harm Reduction Journal, 2022
Background Illicit fentanyl has contributed to a drastic increase in overdose drug deaths. While fentanyl has subsumed the drug supply in the Northeastern and Midwestern USA, it has more recently reached the Western USA.
Sarah S. Shin, Kate LaForge, Erin Stack, Justine Pope, Gillian Leichtling, Jessica E. Larsen, Judith M. Leahy, Andrew Seaman, Daniel Hoover, Laura Chisholm, Christopher Blazes, Robin Baker, Mikaela Byers, Katie Branson, P. Todd Korthuis   +14 more
doaj   +1 more source

“It's my frenemy”: A qualitative exploration of knowledge and perceptions of fentanyl use during the COVID-19 pandemic in people who use drugs at a syringe services program in Philadelphia, PA

Frontiers in Public Health, 2022
BackgroundExacerbated by the COVID-19 pandemic and the proliferation of fentanyl and fentanyl analogs, overdose deaths have surged in the United States, making it important to understand how individuals who use drugs experience and perceive the risks of ...
Sarah Bauerle Bass, Sarah Bauerle Bass, Patrick J. A. Kelly, Sphoorti Pandit-Kerr, Jenine Pilla, Katherine Morris, Erin Larsen, Jennifer P. Wisdom, Phillip R. Torralva   +8 more
doaj   +1 more source

Effects of chronic fentanyl administration on behavioral characteristics of mice

Neuropsychopharmacology Reports, 2019
Background Fentanyl, a synthetic opioid categorized as a narcotic analgesic, has a 100‐ to 200‐fold stronger effect than most opioids, such as morphine. Fatal accidents due to chronic use and abuse of fentanyl are a worldwide social problem.
Kazuki Fujii, Yumie Koshidaka, Mayumi Adachi, Keizo Takao   +3 more
doaj   +1 more source

Comparative study of haemodynamic effects of intravenous ketamine-fentanyl and propofol-fentanyl for laryngeal mask airway insertions in children undergoing herniotomy under general anaesthesia in a nigerian tertiary hospital

Nigerian Postgraduate Medical Journal, 2022
Background: Insertion of laryngeal mask airway (LMA) with propofol in children may cause hypotension, laryngospasm and apnoea. Ketamine and fentanyl have been combined separately with propofol to prevent depression of cardiovascular system during LMA ...
Ajibade Okeyemi, Aliyu Zakari Suleiman, Olubukola Olanrewaju Oyedepo, Benjami Olusomi Bolaji, Babajide Majeed Adegboye, Olufemi Adebayo Ige   +5 more
doaj   +1 more source

Fentanyl for labour pain management: a scoping review

BMC Pregnancy and Childbirth, 2022
Background Labour pain has been identified as an important reason for women to prefer caesarean section (CS). Fentanyl is one of the short acting opioids recommended by World Health Organization for pain relief during labour. This study aimed to identify
Kyaw Lwin Show, Chetta Ngamjarus, Kiattisak Kongwattanakul, Siwanon Rattanakanokchai, Chatuporn Duangkum, Meghan A. Bohren, Ana Pilar Betrán, Monsicha Somjit, Wint Ye Hla Win, Pisake Lumbiganon   +9 more
doaj   +1 more source