Results 51 to 60 of about 195,889 (397)
Systemic Administration of Tempol Attenuates the Cardiorespiratory Depressant Effects of Fentanyl
Frontiers in Pharmacology, 2021 Fentanyl is a high-potency opioid receptor agonist that elicits profound analgesia and suppression of breathing in humans and animals. To date, there is limited evidence as to whether changes in oxidant stress are important factors in any of the actions ...
Santhosh Baby +9 more
doaj +1 more source
Fentanyl vapor self-administration model in mice to study opioid addiction
Science Advances, 2020 Fentanyl vapor self-administration in mice provides a novel and noninvasive model to study opioid addiction. Intravenous drug self-administration is considered the “gold standard” model to investigate the neurobiology of drug addiction in rodents ...
Khaled Moussawi +9 more
semanticscholar +1 more source
Higher doses of naloxone are needed in the synthetic opioid era
Substance Abuse Treatment, Prevention, and Policy, 2019 There has been a dramatic increase of deaths due to illicit fentanyl. We examined the pharmacology of fentanyl and reviewed data on the number of repeat doses of naloxone used to treat fentanyl overdoses.
Ronald B. Moss, Dennis J. Carlo
doaj +1 more source
Asphyxiation with a Fentanyl Patch [PDF]
Case Reports in Oncology, 2013 Narcotics are frequently prescribed to alleviate pain in patients with serious medical illnesses such as cancer. Because of their nonoral route of administration, fentanyl patches are now being frequently prescribed. However, the widespread use of fentanyl patches has been associated with medication errors and misuse [Butts and Jatoi: J Opioid Manag ...
Aaron S. Mansfield, Aminah Jatoi
openaire +4 more sources
Intravenous fentanyl self-administration in male and female C57BL/6J and DBA/2J mice
Scientific Reports, 2023 The genetic mechanisms underlying fentanyl addiction, a highly heritable disease, are unknown. Identifying these mechanisms will lead to better risk assessment, early diagnosis, and improved intervention.
Michael Leonardo +4 more
doaj +1 more source
High and Hyper: Fentanyl Induces Psychomotor Side-Effects in Healthy Pigs
Animals, 2023 Analgesic effects of fentanyl have been investigated using behavior. The behavioral effects of fentanyl and possible serotonergic influence are largely unknown.
Nora Digranes +2 more
doaj +1 more source
Harm Reduction Journal, 2020 Background The opioid epidemic has caused an increase in overdose deaths which can be attributed to fentanyl combined with various illicit substances. Drug checking programs have been started by many harm reduction groups to provide tools for users to ...
Tracy-Lynn E. Lockwood +2 more
semanticscholar +1 more source
Spatial Concentration of Opioid Overdose Deaths in Indianapolis: An Application of the Law of Crime Concentration at Place to a Public Health Epidemic [PDF]
, 2019 The law of crime concentration at place has become a criminological axiom and the foundation for one of the strongest evidence-based policing strategies to date.
Carter, Jeremy G. +2 more
core +1 more source
Ain Shams Journal of Anesthesiology, 2020 Background Intravenous lidocaine has been shown to be an analgesic and anti-inflammatory medication with modulation of excessive inflammatory response.
Mostafa K. Abdellatif, Tamer H. Ibrahim
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Microorganisms, 2022 Gut bacteria influence neural circuits in addiction-related behaviors. Given the association between opioid use, gastrointestinal distress, and microbial dysbiosis in humans and mice, we test the hypothesis that interactions between gut bacteria and the ...
Michelle Ren, Shahrdad Lotfipour
doaj +1 more source