Results 11 to 20 of about 1,285,314 (289)
Limiting habenular hyperactivity ameliorates maternal separation-driven depressive-like symptoms
Nature Communications, 2017 Early-life stress primes depression in adulthood. This study shows that early maternal separation leads to lateral habenula (LHb) hyperactivity and causes depressive-like phenotypes, the latter being reversible when LHb hyperactivity is reduced ...
Anna Tchenio +3 more
doaj +1 more source
Somato-Dendritic Regulation of Raphe Serotonin Neurons; A Key to Antidepressant Action
Frontiers in Neuroscience, 2018 Several lines of evidence implicate serotonin (5-hydroxytryptamine, 5-HT)in regulating personality traits and mood control. Serotonergic neurons are classically thought to be tonic regular-firing, “clock-like” neurons.
Emily Quentin +8 more
doaj +1 more source
Encoding many-valued logic in {\lambda}-calculus
, 2020 We extend the well-known Church encoding of two-valued Boolean Logic in $\lambda$-calculus to encodings of $n$-valued propositional logic (for $3\leq n\leq 5$) in well-chosen infinitary extensions in $\lambda$-calculus.
de Vries, Fer-Jan
core +1 more source
The effects of the design and development of a chemistry curriculum reform on teachers’ professional growth: a case study [PDF]
, 2010 A curriculum innovation requires new learning material for students and a preparation program for teachers, in which teacher learning is a key ingredient.
Coenders, Fer +3 more
core +2 more sources
Evidence for suboxic nitrification in recent marine sediments [PDF]
, 2002 The classical scheme of biogeochemical zones (BGZ) is known to be an oversimplification of the microbial processes that occur in organic-rich marine sediments.
Davies, I.M. +6 more
core +2 more sources
Refining the Role of 5-HT in Postnatal Development of Brain Circuits
Frontiers in Cellular Neuroscience, 2017 Changing serotonin (5-hydroxytryptamine, 5-HT) brain levels during critical periods in development has long-lasting effects on brain function, particularly on later anxiety/depression-related behaviors in adulthood.
Anne Teissier +8 more
doaj +1 more source
Scientific Reports, 2021 Proper maternal care is an essential factor of reproductive success in mammals, involving a repertoire of behaviors oriented toward the feeding and care of the offspring.
Aude Muzerelle +8 more
doaj +1 more source
mGluR-LTD at Excitatory and Inhibitory Synapses in the Lateral Habenula Tunes Neuronal Output
Cell Reports, 2016 Excitatory and inhibitory transmission onto lateral habenula (LHb) neurons is instrumental for the expression of positive and negative motivational states.
Kristina Valentinova, Manuel Mameli
doaj +1 more source
Conformational state-dependent regulation of GABAA receptor diffusion and subsynaptic domains
iScience, 2022 Summary: The efficacy of GABAergic synapses relies on the number of postsynaptic GABAA receptors (GABAARs), which is regulated by a diffusion capture mechanism.
Zaha Merlaud +8 more
doaj +1 more source
Neurobiology of Disease, 2019 Parkinson's disease (PD) is characterized by severe locomotor deficits due to the disappearance of dopamine (DA) from the dorsal striatum. The development of PD symptoms and treatment-related complications such as dyskinesia have been proposed to result ...
Louise-Laure Mariani +4 more
doaj +1 more source