Results 51 to 60 of about 1,285,314 (289)

Neuronal migration and its disorders affecting the CA3 region

Frontiers in Cellular Neuroscience, 2014
In this review, we focus on CA3 neuronal migration disorders in the rodent. We begin by introducing the main steps of hippocampal development, and we summarize characteristic hippocampal malformations in human.
Richard eBelvindrah, Richard eBelvindrah, Richard eBelvindrah, Marika eNosten-Bertrand, Marika eNosten-Bertrand, Marika eNosten-Bertrand, Fiona eFrancis, Fiona eFrancis, Fiona eFrancis   +8 more
doaj   +1 more source

eXnet: An Efficient Approach for Emotion Recognition in the Wild

Sensors, 2020
Facial expression recognition has been well studied for its great importance in the areas of human−computer interaction and social sciences. With the evolution of deep learning, there have been significant advances in this area that also surpass ...
Muhammad Naveed Riaz, Yao Shen, Muhammad Sohail, Minyi Guo   +3 more
doaj   +1 more source

Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse

Frontiers in Neuroscience, 2023
Over the last decade, a large variety of alterations of the Contactin Associated Protein 2 (CNTNAP2) gene, encoding Caspr2, have been identified in several neuronal disorders, including neurodevelopmental disorders and peripheral neuropathies.
Carmen Cifuentes-Diaz, Carmen Cifuentes-Diaz, Carmen Cifuentes-Diaz, Giorgia Canali, Giorgia Canali, Giorgia Canali, Marta Garcia, Marta Garcia, Marta Garcia, Mélanie Druart, Mélanie Druart, Mélanie Druart, Taylor Manett, Taylor Manett, Taylor Manett, Mythili Savariradjane, Mythili Savariradjane, Mythili Savariradjane, Camille Guillaume, Camille Guillaume, Camille Guillaume, Corentin Le Magueresse, Corentin Le Magueresse, Corentin Le Magueresse, Laurence Goutebroze, Laurence Goutebroze, Laurence Goutebroze   +26 more
doaj   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Fer química

Educació Química, 2010
Es presenta una experiència feta amb alumnat de tercer d'ESO de diferents instituts d'educació secundària deCatalunya en el marc de l'experiència innovadora anomenada «Campus Ítaca» de la Universitat Autònoma deBarcelona (UAB), que té com a objectiu animar els estudiants a seguir els seus estudis.
Izquierdo i Aymerich, Mercè, Merino Rubilar, Cristian   +1 more
openaire   +4 more sources

Entre pays et paysages

Géographie et Cultures, 2005
Rurutu Island, in the French Polynesian Archipelago, is experiencing since 1995 a tourism development linked to the seasonal presence of the humpback whale.
Yannick Fer, Gwendoline Malogne‑Fer
doaj   +1 more source

CXCL12 targets the primary cilium cAMP/cGMP ratio to regulate cell polarity during migration

Nature Communications, 2023
Directed cell migration requires sustained cell polarisation. In migrating cortical interneurons, nuclear movements are directed towards the centrosome that organises the primary cilium signalling hub.
Melody Atkins, Maud Wurmser, Michèle Darmon, Fiona Roche, Xavier Nicol, Christine Métin   +5 more
doaj   +1 more source

Inhibition of Focal Adhesion Restricts Chemoresistance in Pancreatic Cancer by Targeting SLC7A11 Mediated Ferroptosis

Advanced Science, EarlyView.
FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang, Hui Yang, Baoyuan Zhang, Yongsu Ma, Kuangen Zhang, Peng Wang, Jiapeng Yang, Zaiqi Wang, Rong Liu, Xiaodong Tian, Ning Zhang, Yinmo Yang   +11 more
wiley   +1 more source

Absolutely Feasible Synchronous Reluctance Machine Rotor Barrier Topologies with Minimal Parametric Complexity

Machines, 2022
The first step in the synchronous reluctance machine design is the selection of rotor flux barrier type. The literature provides various barrier construction methods with a common goal of reducing parametric complexity.
Branko Ban, Stjepan Stipetic
doaj   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source