Results 31 to 40 of about 7,262 (231)
mBio, 2019 Control of electron flux is critical in both natural and bioengineered systems to maximize energy gains. Both small molecules and proteins shuttle high-energy, low-potential electrons liberated during catabolism through diverse metabolic landscapes ...
Brett W. Burkhart +2 more
doaj +1 more source
Ferredoxin binding site on ferredoxin: NADP+ reductase [PDF]
European Journal of Biochemistry, 1993 The chloroplast enzyme ferredoxin:NADP+ reductase (FNR) catalyzes the reduction of NADP+ by ferredoxin (Fd). FNR and Fd form a 1:1 complex that is stabilized by electrostatic interactions between acidic residues of Fd and basic residues of FNR. To localize lysine residues at the Fd binding site of FNR, the FNR:Fd complex (both proteins from spinach ...
I, Jelesarov +5 more
openaire +2 more sources
mBioNitrogenases are the only enzymes able to fix gaseous nitrogen into bioavailable ammonia and hence are essential for sustaining life. Catalysis by nitrogenases requires both a large amount of ATP and electrons donated by strongly reducing ferredoxins or ...
Holly Addison +3 more
doaj +1 more source
Advanced Science, EarlyView.Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He +8 more
wiley +1 more source
AMB Express, 2019 A diversity of softwood lignin depolymerization processes yield guaiacol as the main low molecular weight product. This key aromatic compound can be utilized as a carbon source by several microbial species, most of which are Gram positive bacteria ...
Javier García-Hidalgo +4 more
doaj +1 more source
A highly stable plastidic-type ferredoxin-NADP(H) reductase in the pathogenic bacterium Leptospira interrogans. [PDF]
PLoS ONE, 2011 Leptospira interrogans is a bacterium that is capable of infecting animals and humans, and its infection causes leptospirosis with a range of symptoms from flu-like to severe illness and death.
Daniela L Catalano-Dupuy +3 more
doaj +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Growth-promoting effect on iron-sulfur proteins on axenic cultures of Entamoeba dispar
Parasite, 2006 A growth-promoting factor (GPF) that promotes the growth of Entamoeba dispar under axenic culture conditions was found in fractions of mitochondria (Mt), hydrogenosomes (Hg) and chloroplasts (Cp) obtained from cells of six different protozoan, mammalian ...
Khalifa S.A.M. +5 more
doaj +1 more source
Advanced Science, EarlyView.A redox‐active conductive carrier of tannic acid‐modified iron‐biochar with superior wettability is demonstrated to regulate direct electron transfer at the anaerobic biofilm‐carrier interface by enhancing the cytochrome c‐mediated pathway. For the first time, integrated evidence from spectroscopy, electrochemical analyses, and metatranscriptomics ...
Junli Tian +5 more
wiley +1 more source
Advanced Science, EarlyView.A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang +9 more
wiley +1 more source