Functionalization and Characterization of Magnetic Nanoparticles for the Detection of Ferritin Accumulation in Alzheimer's Disease [PDF]
, 2018 Early diagnosis in Alzheimer's disease (AD), prior to the appearance of marked clinical symptoms, is critical to prevent irreversible neuronal damage and neural malfunction that lead to dementia and death.
Cussó, Lorena +4 more
core +1 more source
Iron-based ferritin nanocore as a contrast agent [PDF]
, 2010 Self-assembling protein cages have been exploited as templates for nanoparticle synthesis. The ferritin molecule, a protein cage present in most living systems, stores excess soluble ferrous iron in the form of an insoluble ferric complex within its ...
Johnson, Eric +4 more
core +2 more sources
Ferritin in cancer therapy: A pleiotropic tumoraffin nanocage‐based transport
Cancer Medicine, 2023 Background Ferritin, a ubiquitously distributed iron storage protein, can specifically target tumor cells through transferrin receptor 1. Due to its rearrangeable nanocage structure, ferritin can be loaded with anticancer drugs.
Guodong Deng +13 more
doaj +1 more source
Electronic structure of nanoscale iron oxide particles measured by scanning tunneling and photoelectron spectroscopies [PDF]
, 2005 We have investigated the electronic structure of nano-sized iron oxide by scanning tunnelling microscopy (STM) and spectroscopy (STS) as well as by photoelectron spectroscopy.
C. A. Johnson +10 more
core +1 more source
Ferritin-based nanomedicine for disease treatment
Medical Review, 2023 Ferritin is an endogenous protein which is self-assembled by 24 subunits into a highly uniform nanocage structure. Due to the drug-encapsulating ability in the hollow inner cavity and abundant modification sites on the outer surface, ferritin nanocage ...
Zhu Yuanjun +7 more
doaj +1 more source
Enhanced Cellular Uptake of H-Chain Human Ferritin Containing Gold Nanoparticles
Pharmaceutics, 2021 Gold nanoparticles (AuNP) capped with biocompatible layers have functional optical, chemical, and biological properties as theranostic agents in biomedicine.
Italo Moglia +5 more
doaj +1 more source
Randomized trial comparing proactive, high-dose versus reactive, low-dose intravenous iron supplementation in hemodialysis (PIVOTAL) : Study design and baseline data [PDF]
, 2018 Background: Intravenous (IV) iron supplementation is a standard maintenance treatment for hemodialysis (HD) patients, but the optimum dosing regimen is unknown.
Anker, Stefan D. +12 more
core +4 more sources
Salt-Dependent Aggregation and Assembly of -Expressed Ferritin
Dose-Response, 2016 Ferritin, with the primary function of iron storage, is a nearly ubiquitous protein found in most living organisms. Our recent investigations suggest that ferritin can assemble nanoparticles.
Wei Sun +7 more
doaj +1 more source
Characterization Analysis of Human Anti-Ferritin Autoantibodies
Antibodies, 2014 Anti-ferritin autoantibodies are found in many animals. Human ferritin-binding proteins (FBPs) were partially purified from human serum by ion-exchange chromatography and immobilized metal affinity chromatography with Zn2+.
Shusaku Higashi +4 more
doaj +1 more source
Effects of the Zanzibar School-Based Deworming Program on Iron Status of Children. [PDF]
, 1998 We evaluated the effects of the Zanzibar school-based deworming program on the iron status of primary school children. Parasitologic and nutritional assessments were carried out at baseline, 6 mo, and 12 mo in 4 nonprogram schools (n = 1002), 4 schools ...
Albonico, M +5 more
core +1 more source