Results 1 to 10 of about 52,157 (235)

Decrease in excitatory neurons, astrocytes and proliferating progenitors in the cerebral cortex of mice lacking exon 3 from the Fgf2 gene [PDF]

BMC Neuroscience, 2008
Background The Fgf2 gene is expressed in the brain neuroepithelium during embryonic development and in astroglial cells throughout life. Previous knockout studies suggested that FGF2 plays a role in the proliferation of neural progenitors in the ...
Sanford L Philip, Doetschman Thomas, Shin Dana, Ohkubo Yasushi, Chen Kesi, Li Hongqi, Vaccarino Flora M   +6 more
doaj   +4 more sources

FGF2 Attenuated Inflammation-Mediated Cardiac Damage: A Novel Mechanistic Insight into the AMPK–FUNDC1–Mitophagy [PDF]

Research
Septic cardiomyopathy, a severe complication of sepsis, is characterized by high morbidity and mortality rates, and its effective management remains an important challenge.
Pingjun Zhu, Xi Wang, Xinjie Han, Yan Wang, Yongkai Ding, Min Zhu, Xin Zhang, Qian Xu, Yukun Li, Zhongxuan Li, Zhi Lu, Qi Zhang, Yan Yin, Guogang Xu, Yingzhen Du   +14 more
doaj   +2 more sources

Plasma membrane transbilayer asymmetry of PI(4,5)P2 drives unconventional secretion of Fibroblast Growth Factor 2 [PDF]

Nature Communications
Unconventional secretion of Fibroblast Growth Factor 2 (FGF2) is mediated by direct translocation across the plasma membrane. This process is initiated by PI(4,5)P2-dependent FGF2 oligomerization at the inner plasma membrane leaflet.
Manpreet Kaur, Fabio Lolicato, Walter Nickel   +2 more
doaj   +2 more sources

Nuclear FGF2 orchestrates phase separation-mediated rDNA chromatin architecture to control BMSCs cell fate [PDF]

Bone Research
Ribosomal RNA (rRNA) synthesis is intricately tied to cellular growth and proliferation. Basic fibroblast growth factor (FGF2), a pivotal factor for bone marrow mesenchymal stem cells (BMSCs), can stimulates rRNA transcription, though the underlying ...
Hengguo Zhang, Zifei Wang, Zhenqing Liu, Xuan Li, Wansu Sun, Wenyu Zhen, Fei Xu, Rui Wang, Qi Yin, Shuqin Cao, Mingyue Wu, Jiacai He, Jianguang Xu, Yang Li, Quan Yuan   +14 more
doaj   +2 more sources

The Effect of Altered Mucin1, FGF2, and HBEGF Gene Expression at The Ectopic Implantation Site and Endometrial Tissues in The Tubal Pregnancy Pathogenesis: A Case-Control Study [PDF]

International Journal of Fertility and Sterility, 2023
Background: Ectopic pregnancy (EP) is defined as implantation and development of an embryo outside of the uterinetissue. Women undergoing assisted reproductive technologies (ART), particularly frozen embryo transfer (FET), arein high-risk populations for
Nadia Noghrehalipour, Reza Aflatoonian, Ali Rahimipour, Samaneh Aghajanpour, Aida Najafian, Zahra Chekini, Firouzeh Ghaffari, Faranak Kazerouni   +7 more
doaj   +1 more source

Placental vascularization in middle and late gestation in the pig

Reproduction and Fertility, 2022
The aims of this study were to determine the changes in the capillary area density in relation to fetal development, to determine immunoexpression of angiogenic factors and to compare their mRNA expression throughout pig gestation. Samples were collected
Mariana Rita Fiorimanti, Andrea Lorena Cristofolini, María José Moreira-Espinoza, María Belén Rabaglino, Claudio Gustavo Barbeito, Cecilia Inés Merkis   +5 more
doaj   +1 more source

Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]

, 2013
The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
A Mansukhani, AK Coussens, BD Stamper, BK Huang, BU Ang, C Owen, C Yao, CB Harvey, CH Shackleton, CW Li, D Gomez, D Johnson, DC Robinson, DP Rice, DT Gault, G Radetti, G Ramajayam, GA Brent, GM Morriss-Kay, GR Williams, H Kohara, H Miraoui, HJ Kim, J Connerney, J Esparza, J Zumbrunn, JA Greenwald, Jack C. Yu, James J. Cray, JH Bassett, JH Oh, JL Penfold, JM Britto, JQ Feng, JS Morey, K Kasono, KA Kapp-Simon, Kameron Khaksarfard, KM Lee, M Bodo, M Menking, M Segni, MH Sheng, MM Cohen Jr, Mohammed Elsalanty, PJ Marie, R Rice, S Akita, S Wadhwa, S Weiss, SA Boyadjiev, SA Rasmussen, Seth M. Weinberg, W Arlt, W Riggs Jr, WM Chadduck, Xing-Ming Shi, Y Xiong, Z von Marschall   +58 more
core   +12 more sources

Photothermal raster image correlation spectroscopy of gold nanoparticles in solution and on live cells [PDF]

Royal Society Open Science, 2015
Raster image correlation spectroscopy (RICS) measures the diffusion of fluorescently labelled molecules from stacks of confocal microscopy images by analysing correlations within the image.
D. J. Nieves, Y. Li, D. G. Fernig, R. Lévy   +3 more
doaj   +1 more source

Fibroblast Growth Factor-2 Levels are Elevated in The Serum of Patients with Multiple Sclerosis [PDF]

Iranian Journal of Immunology, 2022
Background: Various factors contribute to the pathogenesis of Multiple Sclerosis (MS), one of which is Fibroblast Growth Factor 2 (FGF2). The function of FGF2 is pleiotropic.
Maryam Jari, Javad Sadeghi allah abadi, Davood Fathi, Marzieh Attar, Zahra Maleki, Majid Shahbazi   +5 more
doaj   +1 more source

Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]

, 2006
We report a multiwavelength (X-ray, ultraviolet/optical/infrared, radio) analysis of the relativistic tidal disruption event candidate Sw J2058+05 from 3 months to 3 yr post-discovery in order to study its properties and compare its behavior with that of
Bower, Geoffrey C., Brown, Gregory C., Cenko, S. Bradley, Dolan, Stephen, Filippenko, Alexei V., Fruchter, Andrew S., Greiner, Jochen, Horesh, Assaf, Hounsell, Rebekah A., Levan, Andrew J., O'Brien, Paul T., Page, Kim L., Pasham, Dheeraj R., Rau, Arne, Tanvir, Nial R., Wiersema, Klaas   +15 more
core   +5 more sources