Results 21 to 30 of about 38,475 (260)
Frontiers in Immunology, 2022 Serine proteases has been considered to be closely associated with the inflammatory response and tumor progression. As a novel serine protease, the biological function of PRSS23 is rarely studied in cancers.
Shanshan Qin +4 more
semanticscholar +1 more source
Up‐regulated cten by FGF2 contributes to FGF2‐mediated cell migration [PDF]
Molecular Carcinogenesis, 2013 AbstractCten is a focal adhesion molecule that is expressed at very low levels in most normal tissues. Nonetheless, its expression has been found to increase dramatically in many types of cancer including colorectal, breast, gastric, and pancreatic cancer, suggesting that cten may play a critical role during tumorigenesis.
Shih-Ya, Hung +3 more
openaire +2 more sources
Oncogene, 2021 Although radiotherapy is a well-known effective non-surgical treatment for malignant gliomas, the therapeutic efficacy is severely limited due to the radioresistance of tumor cells.
Yu Zhang +9 more
semanticscholar +1 more source
The neuroprotective mechanism of sevoflurane in rats with traumatic brain injury via FGF2
Journal of Neuroinflammation, 2022 Background Traumatic brain injury (TBI) is a kind of acquired brain injury, which is caused by external mechanical forces. Moreover, the neuroprotective role of sevoflurane (Sevo) has been identified in TBI.
Zhong-yu Wang +9 more
semanticscholar +1 more source
Fibroblast Growth Factor-2 Levels are Elevated in The Serum of Patients with Multiple Sclerosis [PDF]
Iranian Journal of Immunology, 2022 Background: Various factors contribute to the pathogenesis of Multiple Sclerosis (MS), one of which is Fibroblast Growth Factor 2 (FGF2). The function of FGF2 is pleiotropic.
Maryam Jari +5 more
doaj +1 more source
Cell Death and Disease, 2021 Metastasis is the predominant reason for high mortality of hepatocellular carcinoma (HCC) patients. It is critical to explore the molecular mechanism underlying HCC metastasis.
Danfei Liu +9 more
semanticscholar +1 more source
Brain Research Bulletin, 2021 Studies have shown that basic fibroblast growth factor (FGF2) is a neurotrophic factor associated with depression. Electroacupuncture (EA) has been shown to be an effective treatment for depression.
Zengyu Yao +6 more
semanticscholar +1 more source
Archives of Medical Science, 2021 Introduction The purpose of this study was to explore the regulatory mechanisms of FGF2 on carotid atherosclerotic plaque development using bioinformatics analysis.
Jian Li +4 more
doaj +1 more source
Multiple Therapeutic Applications of RBM-007, an Anti-FGF2 Aptamer
Cells, 2021 Vascular endothelial growth factor (VEGF) plays a pivotal role in angiogenesis, but is not the only player with an angiogenic function. Fibroblast growth factor-2 (FGF2), which was discovered before VEGF, is also an angiogenic growth factor.
Yoshikazu Nakamura
semanticscholar +1 more source
The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis [PDF]
Bioscience Reports, 2017 We recently found that integrin αvβ3 binds to fibroblast growth factor (FGF)-αvβ31 (FGF1), and that the integrin-binding defective FGF1 mutant (Arg-50 to glutamic acid, R50E) is defective in signalling and antagonistic to FGF1 signalling. R50E suppressed angiogenesis and tumour growth, suggesting that R50E has potential as a therapeutic.
Mori, Seiji +10 more
openaire +4 more sources