Results 21 to 30 of about 35,769 (259)

The underlying mechanisms of FGF2 in carotid atherosclerotic plaque development revealed by bioinformatics analysis

Archives of Medical Science, 2021
Introduction The purpose of this study was to explore the regulatory mechanisms of FGF2 on carotid atherosclerotic plaque development using bioinformatics analysis.
Jian Li, Haifeng Wang, Chenjie Dong, Junling Huang, Wenlin Ma   +4 more
doaj   +1 more source

Fibroblast growth factor-2 bound to specific dermal fibroblast-derived extracellular vesicles is protected from degradation

Scientific Reports, 2022
Fibroblast growth factor-2 (FGF2) has multiple roles in cutaneous wound healing but its natural low stability prevents the development of its use in skin repair therapies.
Isabelle Petit, Ayelet Levy, Soline Estrach, Chloé C. Féral, Andrea Gonçalves Trentin, Florent Dingli, Damarys Loew, Jieqiong Qu, Huiqing Zhou, Clotilde Théry, Céline Prunier, Daniel Aberdam, Olivier Ferrigno   +12 more
doaj   +1 more source

ADAMDEC1 and FGF2/FGFR1 signaling constitute a positive feedback loop to maintain GBM cancer stem cells

Molecular & Cellular Oncology, 2020
Identification of targetable mechanisms that maintain glioblastoma cancer stem cells (CSCs) remain a priority. Our study reveals a new mechanism by which a disintegrin and metalloproteinase domain-like protein decysin 1 promotes CSC maintenance through ...
Ana Jimenez-Pascual, Justin D. Lathia, Florian A. Siebzehnrubl   +2 more
doaj   +1 more source

Dimerization capacities of FGF2 purified with or without heparin-affinity chromatography. [PDF]

PLoS ONE, 2014
Fibroblast growth factor-2 (FGF2) is a pleiotropic growth factor exhibiting a variety of biological activities. In this article, we studied the capacity of FGF2 purified with or without heparin affinity chromatography to self-associate. Analyzing the NMR
Natalia Platonova, Géraldine Miquel, Liang-Yuan Chiu, Said Taouji, Elisabetta Moroni, Giorgio Colombo, Eric Chevet, Shih-Che Sue, Andreas Bikfalvi   +8 more
doaj   +1 more source

Associations of Plasma FGF2 Levels and Polymorphisms in the FGF2 Gene with Obesity Phenotypes in Han Chinese Population [PDF]

Scientific Reports, 2016
AbstractObesity is highly heritable, but the specific genes influencing obesity related traits are largely unknown. Fibroblast growth factor 2 (FGF2) could influence adipocyte differentiation. However, the association of FGF2 polymorphisms and obesity remains unclear.
Ruo-Han Hao, Yan Guo, Shan-Shan Dong, Gai-Zhi Weng, Han Yan, Dong-Li Zhu, Xiao-Feng Chen, Jia-Bin Chen, Tie-Lin Yang   +8 more
openaire   +2 more sources

Mathematical analysis of a model for the growth of the bovine corpus luteum [PDF]

, 2013
The corpus luteum (CL) is an ovarian tissue that grows in the wound space created by follicular rupture. It produces the progesterone needed in the uterus to maintain pregnancy.
Mann, George, Jeffrey, Mike R., Owen, Marcus, Prokopiou, Sotiris, Prokopiou, Sotiris A., Owen, Markus R., Byrne, Helen, Jeffrey, Mike R, Mann, George E., Byrne, Helen M., Robinson, Robert S., Robinson, RL   +11 more
core   +1 more source

mRNA sequencing reveals the distinct gene expression and biological functions in cardiac fibroblasts regulated by recombinant fibroblast growth factor 2 [PDF]

PeerJ, 2023
After myocardial injury, cardiac fibroblasts (CFs) differentiate into myofibroblasts, which express and secrete extracellular matrix (ECM) components for myocardial repair, but also promote myocardial fibrosis.
Changye Sun, Mengru Bai, Yangyang Jia, Xiangqin Tian, Yonglong Guo, Xinhui Xu, Zhikun Guo   +6 more
doaj   +2 more sources

Hypoxic regulation of the expression of anti-angiogenic genes in U87 glioma cells with loss of function of ern1 signaling enzyme

Біологічні студії, 2012
The angiogenesis is an important component of tumor growth and tightly associated with hypoxia. The expression level of genes related to regulation of angiogenesis (BAI2, SPARC, TIMP1, TIMP2, TIMP3, TIMP4, THBS1, THBS2, ADAMTS5 and FGF2) in glioma ...
K. I. Kubaichuk, D. O. Minchenko, S. V. Danilovskyi, A. Y. Kuznetsova, A. K. Jassim, O. H. Minchenko   +5 more
doaj   +1 more source

FGF2 translationally induced by hypoxia is involved in negative and positive feedback loops with HIF-1alpha. [PDF]

PLoS ONE, 2008
BACKGROUND: Fibroblast growth factor 2 (FGF2) is a major angiogenic factor involved in angiogenesis and arteriogenesis, however the regulation of its expression during these processes is poorly documented.
Caroline Conte, Elodie Riant, Céline Toutain, Françoise Pujol, Jean-François Arnal, Françoise Lenfant, Anne-Catherine Prats   +6 more
doaj   +1 more source

A New Role for FGF2 as an Endogenous Inhibitor of Anxiety [PDF]

The Journal of Neuroscience, 2009
Human postmortem studies have demonstrated that fibroblast growth factor-2 (FGF2) expression is decreased in the brain of depressed individuals. It remained unclear, however, whether this is a consequence of the illness or whether FGF2 plays a primary role in the control of mood and emotions.
Javier A, Perez, Sarah M, Clinton, Cortney A, Turner, Stanley J, Watson, Huda, Akil   +4 more
openaire   +2 more sources