Results 31 to 40 of about 52,157 (235)

The Association Between Salivary FGF2 and Physiological and Psychological Components of the Human Stress Response

Chronic Stress, 2022
Background Fibroblast Growth Factor 2 (FGF2) is a neurotrophic protein that has been implicated as a biomarker for anxiety and depressive disorders, which comprise a significant component of the global burden of disease.
Emma M. Bryant, Rick Richardson, Bronwyn M. Graham   +2 more
doaj   +1 more source

Elongation factor 2-diphthamide is critical for translation of two IRES-dependent protein targets, XIAP and FGF2, under oxidative stress conditions [PDF]

, 2013
Elongation factor-2 (eEF2) catalyzes the movement of the ribosome along the mRNA. A single histidine residue in eEF2 (H715) is modified to form diphthamide. A role for eEF2 in cellular stress responses is highlighted by the fact that eEF2 is sensitive to
Argüelles Castilla, Sandro, Ayala Gómez, Antonio, Camandola, Simonetta, Cutler, Roy G.   +3 more
core   +1 more source

FGF2 translationally induced by hypoxia is involved in negative and positive feedback loops with HIF-1alpha. [PDF]

PLoS ONE, 2008
BACKGROUND: Fibroblast growth factor 2 (FGF2) is a major angiogenic factor involved in angiogenesis and arteriogenesis, however the regulation of its expression during these processes is poorly documented.
Caroline Conte, Elodie Riant, Céline Toutain, Françoise Pujol, Jean-François Arnal, Françoise Lenfant, Anne-Catherine Prats   +6 more
doaj   +1 more source

Expression of the FGFR2c mesenchymal splicing variant in human keratinocytes inhibits differentiation and promotes invasion [PDF]

, 2018
The altered isoform switching of the fibroblast growth factor receptor 2 (FGFR2) and aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells is involved in cancer progression.
Anacker, Barbaresi, Barton, Belleudi, Boukamp, Brooks, Candi, Capone, Chaffer, Dotto, Feng, Gaggioli, Getsios, Goetz, Grose, Harmon, Haugsten, Ishiwata, Izar, Jones, Kawase, Matsuda, Oh, Oltean, Peng, Petiot, Pickard, Pickard, Purpura, Raffa, Ramsey, Ranieri, Ranieri, Shamir, Shih, Simpson, Truong, Turner, Warzecha, Warzecha, Yang, Ye, Zhang, Zhao   +43 more
core   +1 more source

Reversal of Chemotherapy Resistance to Cisplatin in NSCLC by miRNA-195-5p via Targeting the FGF2 Gene

Pharmacogenomics and Personalized Medicine, 2021
Hao Wang,1,2 Zhi-lin Sui,1 Xian-xian Wu,1 Peng Tang,1 Hong-dian Zhang,1 Zhen-tao Yu1,3 1Department of Esophageal Cancer, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy of Tianjin City, Tianjin ...
Wang H, Sui Z, Wu X, Tang P, Zhang H, Yu Z   +5 more
doaj  

Fibroblast Growth Factor 2 Protein Stability Provides Decreased Dependence on Heparin for Induction of FGFR Signaling and Alters ERK Signaling Dynamics

Frontiers in Cell and Developmental Biology, 2019
Fibroblast growth factor 2 (FGF2) plays important roles in tissue development and repair. Using heparan sulfates (HS)/heparin as a cofactor, FGF2 binds to FGF receptor (FGFR) and induces downstream signaling pathways, such as ERK pathway, that regulate ...
Zuzana Koledova, Zuzana Koledova, Jakub Sumbal, Jakub Sumbal, Anas Rabata, Gabin de La Bourdonnaye, Gabin de La Bourdonnaye, Radka Chaloupkova, Radka Chaloupkova, Barbara Hrdlickova, Jiri Damborsky, Jiri Damborsky, Jiri Damborsky, Veronika Stepankova   +13 more
doaj   +1 more source

Effect of Endurance Training and Stem Cell on Fgf2 and Mmp13 Gene Expression in Knee Tissue of Rats with Osteoarthritis

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2021
Introduction: The aim of this study was to investigate the effect of endurance training and stem cell injection on FGF2 and MMP13 gene expression in knee tissue of rats with knee osteoarthritis.
Mahnaz Alinejad, Alireza Barari, Asieh Abbasi Daloii, Parvin Farzanegi   +3 more
doaj  

Investigating the Involvement of Fibroblast Growth Factors in Adipose Tissue Thermogenesis

European Journal of Biology
Objective: Thermogenesis in white and brown adipose tissues can be induced by various stimuli, including cold exposure, β-adrenergic stimulation, and tumor growth.
Serkan Kır
doaj   +1 more source

FGF2 Binding, Signaling, Angiogenesis Are Modulated by Heparanase in Metastatic Melanoma Cells

Neoplasia: An International Journal for Oncology Research, 2006
Heparanase (HPSE) and fibroblast growth factor-2 (FGF2) are critical regulators of melanoma angiogenesis and metastasis. Elevated HPSE expression contributes to melanoma progression; however, further augmentation of HPSE presence can inhibit ...
Jane Reiland, Doty Kempf, Madhuchhanda Roy, Yvonne Denkins, Dario Marchetti   +4 more
doaj   +1 more source

A Cardiac Mitochondrial FGFR1 Mediates the Antithetical Effects of FGF2 Isoforms on Permeability Transition

Cells, 2021
Mitochondria, abundant organelles in high energy demand cells such as cardiomyocytes, can determine cell death or survival by regulating the opening of mitochondrial permeability transition pore, mPTP.
Wattamon Srisakuldee, Barbara E. Nickel, Robert R. Fandrich, Feixong Zhang, Kishore B. S. Pasumarthi, Elissavet Kardami   +5 more
doaj   +1 more source