Results 31 to 40 of about 19,752 (209)
Vitamin D, a modulator of musculoskeletal health in chronic kidney disease [PDF]
, 2017 The spectrum of activity of vitamin D goes beyond calcium and bone homeostasis, and growing evidence suggests that vitamin D contributes to maintain musculoskeletal health in healthy subjects as well as in patients with chronic kidney disease (CKD ...
Jordi Bover +6 more
core +2 more sources
Klotho controls the brain-immune system interface in the choroid plexus. [PDF]
, 2018 Located within the brain's ventricles, the choroid plexus produces cerebrospinal fluid and forms an important barrier between the central nervous system and the blood.
Ho, Kaitlyn +7 more
core +1 more source
Klotho pathways, myelination disorders, neurodegenerative diseases, and epigenetic drugs [PDF]
, 2020 In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by
Chen, Xiaohong +15 more
core +1 more source
International Journal of Nephrology and Renovascular Disease, 2021 Yaser Ammar,1 Amira Mohamed,1 Gihane Khalil,2 Dalia Maharem1 1Internal Medicine Department, Medical Research Institute, Alexandria University, Alexandria, Egypt; 2Chemical Pathology Department, Medical Research Institute, Alexandria University ...
Ammar Y, Mohamed A, Khalil G, Maharem D
doaj
Kidney & Blood Pressure Research, 2021 Introduction: Phosphate homeostasis is regulated by a complex network involving the parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), and calcitriol acting on several organs including the kidney, intestine, bone, and parathyroid gland ...
Nicole Gehring +3 more
doaj +1 more source
Analysis of Thisbe and Pyramus functional domains reveals evidence for cleavage of Drosophila FGFs [PDF]
, 2010 Background: As important regulators of developmental and adult processes in metazoans, Fibroblast Growth Factor (FGF) proteins are potent signaling molecules whose activities must be tightly regulated.
Stathopoulos, Angelike, Tulin, Sarah
core +4 more sources
Pleiotropic Actions of FGF23 [PDF]
Toxicologic Pathology, 2017 Fibroblast growth factor-23 (FGF23) is a bone-derived hormone, mainly produced by osteoblasts and osteocytes in response to increased extracellular phosphate and circulating vitamin D hormone. Endocrine FGF23 signaling requires co-expression of the ubiquitously expressed FGF receptor 1 (FGFR1) and the co-receptor α-Klotho (Klotho).
openaire +2 more sources
Serum fibroblast growth factor 23, serum iron and bone mineral density in premenopausal women [PDF]
, 2016 Fibroblast growth factor 23 (FGF23) circulates as active protein and inactive fragments. Low iron status increases FGF23 gene expression, and iron deficiency is common. We hypothesized that in healthy premenopausal women, serum iron influences C-terminal
Acton, Anthony +7 more
core +1 more source
Frontiers in Physiology, 2018 Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and vitamin D metabolism. In patients with acute kidney injury (AKI), FGF23 levels rise rapidly after onset of AKI and are associated with AKI progression and increased mortality.
Daniela Egli-Spichtig +2 more
doaj +1 more source
Inflammation, iron and vitamin D metabolism in different cardiomyopathy aetiologies
Pteridines, 2020 Immune activation coincides with disturbances in iron and vitamin D metabolism in patients with cardiomyopathy. In this study, we investigated whether there are differences regarding immune activation, iron and vitamin D metabolism between the different ...
Lanser Lukas +6 more
doaj +1 more source