Results 91 to 100 of about 7,115 (188)

SHANK2-FGFR1: A Novel FGFR1 Rearrangement in a Patient with Intestinal Adenocarcinoma

Journal of the College of Physicians and Surgeons Pakistan, 2021
Hongguang, Sheng, Yugang, Jiang, Ling, Li   +2 more
openaire   +3 more sources

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

Cytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu, Mokhtar Abdelhammed, Xu Cao, Nisha S. Ramani   +3 more
wiley   +1 more source

Insight into resistance mechanisms of AZD4547 and E3810 to FGFR1 gatekeeper mutation via theoretical study

, 2017
Donglou Liang,1,* Qiaowan Chen,2,* Yujin Guo,1 Ting Zhang,3 Wentao Guo4 1Pharmacy Department, Jining First People’s Hospital, 2Department of Obstetrics, Affiliated Hospital of Jining Medical University, Jining, Shandong, 3Department of ...
Liang D, Chen Q, Zhang T, Guo Y, Guo W
core  

The consistency of intermolecular hydrogen bonds across the MD simulation (final 10 ns) for FGF2–FGFR1 residues.

, 2017
The occurrence of inter-molecular hydrogen bonds between FGF2–FGFR1 residues (shown on y-axis) and small molecule ligands (NSGMs and HS06) are shown for each frame of the final 10 ns of the MD run.
Nehru Viji Sankaranarayanan (3617105), Balaji Nagarajan (3738106), Umesh R. Desai (299178), Bhaumik B. Patel (1330791)   +3 more
core   +1 more source

Transcriptomic profiling of subpopulations of mouse embryonic subplate neurons

Journal of Anatomy, EarlyView.
To study gene expression in subpopulations of cortical subplate neurons (Lpar1‐EGFP‐positive and D1B‐positive SpN clusters), we applied gene expression profiling, including bulk microarray analysis, single‐cell RNA sequencing (scRNA‐seq), and Visium spatial transcriptomics, and identified both overlapping and unique gene expression signatures ...
Hitomi Achiwa, Yuichiro Hara, Hideya Kawaji, Minori Oshima, Noe Kaneko, Ayumu Morioka, Anna Hoerder‐Suabedissen, Zoltán Molnár, Chiaki Ohtaka‐Maruyama   +8 more
wiley   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Fator de crescimento fibroblástico básico e seus receptores em relação à atividade proliferativa na placenta bubalina em diferentes fases da gestação Basic fibloblast growth factor and its receptors in relation to proliferative activity in the buffalo placenta during gestation

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007
Estudou-se a distribuição espaço-temporal do fator de crescimento fibroblástico básico (bFGF), do receptor 1 do fator de crescimento fibroblástico (FGFR1) e do receptor 2 do fator de crescimento fibroblástico (FGFR2) na placenta bubalina, correlacionando-
L.P. Artoni, C.E.B. Moura, E.M. Barbosa Jr, D.B. Campos, F.T.V Pereira, P.C. Papa   +5 more
doaj   +1 more source

Immune platelet transfusion refractoriness associated with anti‐CD36 alloimmunisation in a Brazilian patient with platelet CD36 deficiency

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Immune platelet transfusion refractoriness (PTR) is usually mediated by anti‐HLA class I antibodies; immunisation against CD36 (platelet glycoprotein IV [GPIV]) is relatively rare. Platelet CD36 deficiency shows marked ethnic variability and is seldom reported in admixed Latin American populations.
Rayane Dayse Alves Conserva, Luiz Frederico Bezerra Honorato Junior, Ana Paula Hitomi Yokoyama, Thiago Henrique Costa, Luis Henrique Cardoso Fedeli, Ana Cynira Franco Marret, Eduardo Perez Bastos, Fabio Pires de Souza Santos, Luana Nobrega Costa, Livia Chiosini de Nadai, Carolina Bonet‐Bub, Jose Mauro Kutner   +11 more
wiley   +1 more source

FGFR1 and FGFR4 oncogenicity depends on n-cadherin and their co-expression may predict FGFR-targeted therapy efficacy

, 2020
Fondos FEDERBackground Fibroblast growth factor receptor (FGFR)1 and FGFR4 have been associated with tumorigenesis in a variety of tumour types. As a therapeutic approach, their inhibition has been attempted in different types of malignancies, including ...
Quintanal Villalonga, Álvaro, Ojeda Márquez, Laura, López-Ríos Moreno, Fernando, Paz-Ares Rodríguez, Luis Gonzaga   +3 more
core   +1 more source

miRNA-133b targets FGFR1 and presents multiple tumor suppressor activities in osteosarcoma

Cancer Cell International, 2018
Background Osteosarcoma (OS) is the most common bone malignancy prevalent in children and young adults. MicroRNA-133b (miR-133b), through directly targeting the fibroblast growth factor receptor 1 (FGFR1), is increasingly recognized as a tumor suppressor
Gan Gao, Zhen Tian, Huan-Ye Zhu, Xun-Yan Ouyang   +3 more
doaj   +1 more source