Results 141 to 150 of about 7,115 (188)
Mutated FGFR1 is an oncogenic driver and therapeutic target in high-risk neuroblastoma
Fibroblast growth factor receptor 1 (FGFR1) is recurrently mutated at p.N546 in neuroblastoma. We here sought to examine whether mutant FGFR1 is an oncogenic driver, a predictive biomarker, and an actionable vulnerability in this malignancy.Ibruli, Nadliv, Rognlien, Anne Gro Wesenberg, Hellmann, Anna-Maria, Grüll, Holger, Kahlert, Yvonne, Chesler, Louis, Shukla, Neerav N., Hero, Barbara, Iglesias, Fiorella, Schramm, Kathrin, Schleiermacher, Gudrun, Westermann, Frank, Reinhardt, H. Christian, Werner, Jan-Michael, Henssen, Anton G., Petersen, Josephine, Höppner, Stefanie, Thomas, Roman K., Gunnes, Maria Winther, George, Sally L., Masliah-Planchon, Julien, Witt, Olaf, Molenaar, Jan, Eggert, Angelika, Barone, Giuseppe, Boland, Jana, Malchers, Florian, Bernkopf, Marie, Bagatell, Rochelle, Simon, Thorsten, Schulte, Johannes H., Rosswog, Carolina, Schultheis, Anne M., Hemstedt, Nadine, Büttner, Reinhard, Bartenhagen, Christoph, Werr, Lisa, Peifer, Martin, Hughes, Debbie, Fischer, Matthias, Decarolis, Boris, Langenberg, Karin Ps, Capasso, Mario, Dammert, Marcel A., Surrey, Lea F., Taschner-Mandl, Sabine, Beiske, Klaus Hermann, Bagatell, R, Grüll, H, Ibruli, N, Schulte, JH, Chesler, L, Reinhardt, HC, Schramm, K, Decarolis, B, Bernkopf, M, Beiske, Klaus H, Eggert, A, Witt, O, Langenberg, Karin P, Capasso, M, Dammert, MA, Rosswog, C, Thomas, Roman K, Langenberg, KP, Shukla, Neerav N, Boland, J, Dammert, Marcel A, George, Sally L, Hero, B, Schleiermacher, G, Masliah-Planchon, J, Simon, T, Büttner, R, Rognlien, AGW, Taschner-Mandl, S, Gunnes, MW, Reinhardt, H Christian, Surrey, LF, Henssen, Anton G, George, SL, Peifer, M, Schulte, Johannes H, Iglesias, F, Thomas, RK, Bartenhagen, C, Höppner, S, Petersen, J, Molenaar, J, Barone, G, Shukla, NN, Fischer, M, Hellmann, A-M, Beiske, KH, Hughes, D, Surrey, Lea F, Henssen, AG, Werner, J-M, Malchers, F, Schultheis, AM, Hemstedt, N, Schultheis, Anne M, Westermann, F, Werr, L, Kahlert, Y +104 morecore +1 more sourceThe FGFR1 N546K mutation confers resistance to pemigatinib in MLN-ZMYM2::FGFR1
LeukemiaKhalid Shoumariyeh, Stefan Haug, Juliana Schwaab, Julie K. Pfeil, Jannis Stappenbeck, Annette Schmitt-Graeff, Nicole Naumann, Greta Waltemode, Robert Zeiser, Cornelius Miething, Wolf-Karsten Hofmann, Manja Meggendorfer, Sven Diederichs, Justus Duyster, Andreas Reiter +14 moreopenaire +3 more sourcesAnti-FGFR1 aptamer-tagged superparamagnetic conjugates for anticancer hyperthermia therapy
, 2017 Przemysław M Jurek,* Konrad Zabłocki,* Urszula Waśko, Maciej P Mazurek, Jacek Otlewski, Filip Jeleń Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Poland *These authors contributed equally to this work Abstract ...Otlewski J, Jurek PM, Waśko U, Zabłocki K, Mazurek MP, Jeleń F +5 morecore
