Results 41 to 50 of about 6,610 (202)

Circ_0000885 Enhances Osteosarcoma Progression by Increasing FGFR1 Expression via Sponging MiR-1294

Cancer Management and Research, 2020
Yinxian Chen, Sicheng Zhang, Chuanqing Bai, Zhiye Guan, Wenjian Chen Department of Orthopedic, Children’s Hospital of Anhui Medical University, Hefei, Anhui 230032, People’s Republic of ChinaCorrespondence: Wenjian ChenDepartment of ...
Chen Y, Zhang S, Bai C, Guan Z, Chen W
doaj  

Fibroblast growth factor receptor 1 amplification in laryngeal squamous cell carcinoma. [PDF]

PLoS ONE, 2018
Fibroblast growth factor receptor 1 (FGFR1) has been noted to be amplified in a variety of squamous cell carcinomas (SCCa) of the head, neck, and lung and increased copy number (CN) is a predictor of poor outcomes.
Jesus Monico, Brandon Miller, Luminita Rezeanu, Warren May, Donna C Sullivan   +4 more
doaj   +1 more source

Dmp1-Cre-mediated conditional deletion of Fgfr1 from the floxed Fgfr1 allele (Fgfr1^flox) in different tissues.

, 2014
(A) Schematic illustration of wild-type (Fgfr1+), floxed Fgfr1 allele before (Fgfr1flox) and after deletion (Fgfr1Δflox) of the lox P cassette containing Exon 8–14 via Cre-mediated recombination.
Yingjuan Liang (608326), Leigh Darryl Quarles (306499), Zhousheng Xiao (306496), Li Cao (106383), Jinsong Huang (308466), Xiaobin Han (608327)   +5 more
core   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Dual roles of endothelial FGF-2-FGFR1-PDGF-BB and perivascular FGF-2-FGFR2-PDGFRβ signaling pathways in tumor vascular remodeling.

, 2018
Perivascular cells are important cellular components in the tumor microenvironment (TME) and they modulate vascular integrity, remodeling, stability, and functions.
X Yang (5161994), O Dubey (7718567), X Wang (1378959), K Hosaka (7653353), Y Cao (7653362), T Seki (7653350), Y Yang (6099497), M Scherzer (7803833), M Nakamura (7803827), P Andersson (7803830), Y Zhang (5998940)   +10 more
core   +6 more sources

Circ_0015756 Aggravates Hepatocellular Carcinoma Development by Regulating FGFR1 via Sponging miR-610

Cancer Management and Research, 2020
Weisheng Guo,1 Lin Zhao,1 Guangya Wei,1 Peng Liu,1 Yu Zhang,1 Liran Fu2 1Department of Hepatobiliary Surgery, Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine ...
Guo W, Zhao L, Wei G, Liu P, Zhang Y, Fu L   +5 more
doaj  

Reciprocal regulatory mechanism between miR-214-3p and FGFR1 in FGFR1-amplified lung cancer [PDF]

Oncogenesis, 2019
AbstractMicroRNA (miRNA) and fibroblast growth factor receptor 1 (FGFR1) dysregulation are considered to play an important role in tumor proliferation, invasion, and metastasis. However, the regulatory mechanism between miRNAs and FGFR1 in lung cancer remains unclear and extremely critical.
Ying Yang, Ziming Li, Hong Yuan, Wenxiang Ji, Kaixuan Wang, Tingting Lu, Yongfeng Yu, Qingyu Zeng, Fan Li, Weiliang Xia, Shun Lu   +10 more
openaire   +2 more sources

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

FGFR1 expression.

, 2015
FGFR1 expression.
Ronald Simon (997), Lia Burkhardt (824184), Susanne Burdak-Rothkamm (824185), Frank Jacobsen (22692), Guido Sauter (124861), Till Krech (121538), Jule Kohlhaussen (824183), Katharina von Loga (500695), Stefan Steurer (514479)   +8 more
core   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source