Results 31 to 40 of about 29,080 (157)
Asian Journal of AndrologyFibroblast growth factor receptor 1 (FGFR1) mutations are associated with congenital hypogonadotropic hypogonadism (CHH) through inheritance or spontaneous occurrence.
Yu-Fan Yang +5 more
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Fibroblast growth factor receptor 1 amplification in laryngeal squamous cell carcinoma. [PDF]
PLoS ONE, 2018 Fibroblast growth factor receptor 1 (FGFR1) has been noted to be amplified in a variety of squamous cell carcinomas (SCCa) of the head, neck, and lung and increased copy number (CN) is a predictor of poor outcomes.
Jesus Monico +4 more
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Circ_0000885 Enhances Osteosarcoma Progression by Increasing FGFR1 Expression via Sponging MiR-1294
Cancer Management and Research, 2020 Yinxian Chen, Sicheng Zhang, Chuanqing Bai, Zhiye Guan, Wenjian Chen Department of Orthopedic, Children’s Hospital of Anhui Medical University, Hefei, Anhui 230032, People’s Republic of ChinaCorrespondence: Wenjian ChenDepartment of ...
Chen Y, Zhang S, Bai C, Guan Z, Chen W
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Cancer Management and Research, 2020 Weisheng Guo,1 Lin Zhao,1 Guangya Wei,1 Peng Liu,1 Yu Zhang,1 Liran Fu2 1Department of Hepatobiliary Surgery, Henan Province Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine ...
Guo W +5 more
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Reciprocal regulatory mechanism between miR-214-3p and FGFR1 in FGFR1-amplified lung cancer [PDF]
Oncogenesis, 2019 AbstractMicroRNA (miRNA) and fibroblast growth factor receptor 1 (FGFR1) dysregulation are considered to play an important role in tumor proliferation, invasion, and metastasis. However, the regulatory mechanism between miRNAs and FGFR1 in lung cancer remains unclear and extremely critical.
Ying Yang +10 more
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npj Precision Oncology, 2022 Lung cancer is the leading cause of cancer-related deaths worldwide. Fibroblast growth factor receptor 1 (FGFR1) gene amplification is one of the most prominent and potentially targetable genetic alterations in squamous-cell lung cancer (SQCLC).
Omar Elakad +12 more
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The sum is greater than the FGFR1 partner [PDF]
Cancer Cell, 2004 Cancer-associated chromosomal translocations create chimeric oncoproteins that contribute to aberrant growth by dominant or dominant negative mechanisms. Interestingly, genes such as MLL, RARA, and EWS are fused to multiple partners. This molecular promiscuity can provide important functional information, as specific translocations may be associated ...
Braun, Benjamin S, Shannon, Kevin
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FGFR1 expression defines clinically distinct subtypes in pancreatic cancer
Journal of Translational Medicine, 2018 Background The clinical significance of fibroblast growth factor receptor 1 (FGFR1) protein expression in pancreatic cancer is largely unknown. In this study, we aimed investigate the clinical significance of FGFR1 expression in pancreatic cancer ...
Farhan Haq +6 more
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Impairment of sperm motility in mice with heterozygous deletion of fibroblast growth factor receptor 1 [PDF]
Jichu yixue yu linchuangObjective To investigate the effect of heterozygous deletion of fibroblast growth factor receptor 1 (FGFR1) on reproductive function in congenital hypogonadotropic hypogonadism (CHH).
LI Chenyang, LI Ting, WANG Xi, NIE Min, WU Xueyan, MAO Jiangfeng, HAN Qin
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Frontiers in Cell and Developmental Biology, 2021 The underlying mechanism of fibroblast growth factor receptor 1 (FGFR1) mediated carcinogenesis is still not fully understood. For instance, FGFR1 upregulation leads to endocrine therapy resistance in breast cancer patients.
Syeda Kiran Riaz +19 more
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