Results 121 to 130 of about 45,688 (235)
Cancer Science, Volume 117, Issue 5, Page 1235-1243, May 2026.RUNX‐dependent transcriptional control of SOS1 reinforces HER2–RAS signaling and may attenuate responses to HER2‐targeted therapies in HER2‐positive gastric cancer. ABSTRACT HER2‐positive gastric cancer represents a distinct molecular subtype characterized by chromosomal instability, variable HER2 amplification, and substantial intratumoral ...
Tatsuya Masuda +3 more
wiley +1 more source
Finding More in Less: Precision Medicine for Pancreatic Cancer Using Residual Cytology Samples
Cytopathology, Volume 37, Issue 3, Page 275-283, May 2026.The study evaluates the use of residual liquid‐based cytology (LBC) samples from pancreatic ductal adenocarcinoma (PDAC) for molecular analysis. It shows that LBC samples preserve nucleic acid quality and remain suitable for next‐generation sequencing (NGS) and MSI testing even after prolonged storage, underscoring their value when other samples are ...
Raquel Antón‐Peñalver +17 more
wiley +1 more source
Fibroblast growth factor receptor 2 (FGFR2) is required for meibomian gland homeostasis in the adult mouse [PDF]
, 2017 Huang, Andrew J. W. +3 more
core +2 more sources
Hepatology Research, Volume 56, Issue 5, Page 853-860, May 2026.ABSTRACT Background and Aim Anti–vascular endothelial growth factor (VEGF) agents are widely used for hepatocellular carcinoma (HCC); inhibition of VEGF‐mediated liver regeneration may compromise hepatic reserve. We investigated the impact of anti‐VEGF therapy on liver function and risk factors for deterioration of albumin–bilirubin (ALBI) score during
Naoshi Nishida +11 more
wiley +1 more source
Molecular pathology of phyllodes tumours of the breast—much more than MED12
Histopathology, Volume 88, Issue 6, Page 1115-1125, May 2026.Phyllodes tumours can develop from fibroadenomas bearing MED12 variants by the development of pTERT alterations (“MED12 pathway”) or de novo (“MED12 independent pathway”). Grade progression is associated with increasing genetic complexity including cancer driver gene aberrations. Molecular alterations can be useful in assigning grade and distinguishing
Jia‐Min B Pang +3 more
wiley +1 more source
Síndrome de Apert, una aproximación para un diagnóstico clínico. Reporte de caso
Salud Uninorte, 2010 Introducción: El síndrome de Apert, o acrocefalosindactilia tipo I, es un síndrome caracterizado por craneosinostosis, acompañada de sindactilia simétrica en las cuatro extremidades, alteraciones maxilofaciales, cutáneas y retardo mental variable.
Diana Ramírez +3 more
doaj
Fibroblast growth factor receptors: their expression and clinicopathological relevance in canine mammary gland tumours [PDF]
, 2014 Mammary gland tumour (CMT) is the most common neoplasm which occurs naturally in dogs. CMT affects mainly female dogs and can lead to metastatic disease and eventually death if untreated.
Dhaliwal, Gurmeet Kaur +6 more
core
Pathways to enhancing prenatal diagnosis of skeletal dysplasias
Pregnancy, Volume 2, Issue 3, May 2026.
Kate Swanson, Mary E. Norton
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.ABSTRACT Gastrointestinal (GI) tumours are one of the most prevalent cancers globally. Even with normal GI function, individuals may develop neoplasms, highlighting the need to better understand the underlying causes of tumorigenesis. The emergence of tumour drug resistance represents the main reason for the failure of drug treatment; thus, it is ...
Mohsen Sharif‐zak +6 more
wiley +1 more source
The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design
ChemMedChem, Volume 21, Issue 7, 14 April 2026.Thalidomide serves as a molecular nexus linking chemistry and biology: advances in synthesis and structural understanding enable protein degradation technologies, while its immunomodulatory activity underpins anti‐inflammatory and anticancer therapies.
Konstantina Nikovia +4 more
wiley +1 more source