Results 121 to 130 of about 37,073 (238)
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman +2 more
wiley +1 more source
, 2017 Supplementary Figure S1. Confirmation of secondary point mutation in FGFR2-ZMYM4 allele. Supplementary Figure S2. Homology between FGFR2 and FGFR3 proteins. Supplementary Figure S3. FGFR2-OPTN fusion detected in all autopsy lesions.
Alberto Bardelli (163979) +31 more
core +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Inherited factors account for a large share of breast cancer susceptibility, yet the biological consequences of most risk variants are still poorly understood. To address this gap, we studied 175 breast cancer risk variants confirmed by genome‐wide association studies and gathered the genes that lie near them.
Sultana Jannat +11 more
wiley +1 more source
Fgfr2 deficiency leads to locomotor deficits in adult mice.
, 2014 (A–D) Cresyl-violet stained brightfield (A,C) and darkfield (B,D) views of sagittal sections from adult Fgfr2lox/lox (control, A,B) and Nestin-Cre;Fgfr2lox/lox (Fgfr2 cKO, C,D) cerebella, hybridized with a radioactive Fgfr2 exon 5 riboprobe.
Sabit Delic (591297) +10 more
core +1 more source
A Ser252Trp substitution in mouse FGFR2 results in hyperplasia of embryonic salivary gland parenchyma [PDF]
, 2021 九州歯科大学博士（歯学）Objectives: Mutations in the fibroblast growth factor receptor 2 (FGFR2) gene are responsible for several severe forms of craniosynostotic disorders, such as Apert and Crouzon syndromes.
Kometani-Gunjigake Kaori +8 more
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Head &Neck, Volume 48, Issue 11, Page 3193-3201, November 2026.ABSTRACT Background Adenoid cystic carcinoma (ACC) is a rare malignancy with a propensity for perineural invasion and hematogenous spread. Central nervous system (CNS) involvement is uncommon, and detailed clinical and genomic data on this aspect of the disease remain limited.
Omar Elghawy +7 more
wiley +1 more source
Liquid Biopsy: Past, Present, and Future
MedComm, Volume 7, Issue 11, November 2026.Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu +8 more
wiley +1 more source
Primers used for FGFR2 promoter constructs.
, 2013 Primers used for FGFR2 promoter constructs.
Sirio D’Amici (403067) +6 more
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MedComm, Volume 7, Issue 11, November 2026.This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin +6 more
wiley +1 more source
The multifaceted roles and mechanisms of necroptosis in cancer cells remain incompletely understood. Here, we demonstrate that FGFR2 inhibition potently inhibits esophageal squamous cell carcinoma (ESCC) by inducing necroptosis in a RIP1/MLKL-dependent ...
Dongshao Chen +15 more
core +1 more source