Results 91 to 100 of about 2,012 (174)

Expression and signaling of the tyrosine kinase FGFR2b/KGFR regulates phagocytosis and melanosome uptake in human keratinocytes

, 2010
Membrane and actin cytoskeleton dynamics during phagocytosis can be triggered and amplified by the signal transduction of receptor tyrosine kinases.
Flavia Persechino, Maria Rosaria Torrisi, F. Persechino, Laura Leone, Cristina Scrofani, PURPURA, VALERIA, TORRISI, Maria Rosaria, Valeria Purpura, Francesca Belleudi, BELLEUDI, Francesca, SCROFANI, CRISTINA, LEONE, LAURA   +11 more
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بیان و تخلیص ناحیه‌ی کینازی پروتئین نوترکیب گیرنده‌ی عامل رشد فیبروبلاستی نوع 2b و بررسی تغییرات ساختاری آن بر اثر برهم‌کنش آن با گالیک اسید

مجله دانشکده پزشکی اصفهان, 2016
مقدمه: گیرنده‌ی‏ عامل رشد فیبروبلاستی 2b (FGFR2b یا Fibroblast growth factor receptor 2b) در مسیر پیام‏رسانی سلولی و تنظیم فرایندهای مهم زیستی نظیر تمایز و تکثیر سلولی نقش اساسی دارد.
Faezeh Seyyed-Attaran, Dariush Ilghari, Nematollah Gheibi, Mehdi Sahmani, Hossein Piri   +4 more
doaj  

FGF10 Signaling in Heart Development, Homeostasis, Disease and Repair

Frontiers in Genetics, 2018
Essential muscular organ that provides the whole body with oxygen and nutrients, the heart is the first organ to function during embryonic development.
Fabien Hubert, Sandy M. Payan, Francesca Rochais   +2 more
doaj   +1 more source

Advanced progress in research and diagnosis of gastric cancer in 2022

Zhongguo aizheng zazhi, 2023
Gastric cancer is one of the malignant tumors with high incidence in China, with a 5-year relative survival rate of about 40%, which is characterized by low early diagnosis rate, large tumor load, high heterogeneity and poor prognosis.
Jinling JIANG, Chenfei ZHOU, Chao WANG, Liqin ZHAO, Junwei WU, Jun ZHANG   +5 more
doaj  

Translational research in acute lung injury and pulmonary fibrosis attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair

, 2020
© 2015 the American Physiological Society Fibroblast growth factors (Fgfs) mediate organ repair. Lung epithelial cell overexpression of Fgf10 postbleomycin injury is both protective and therapeutic, characterized by increased survival and attenuated ...
Henneke I., Quantius J., Königshoff M., Li X., Wilhelm J., Jones M., Rizvanov A., Hezel S., Herold S., Goth K., Bellusci S., Agha E., Seeger W., Günther A., Mackenzie B., Alam D., Chao C.   +16 more
core  

Translational research in acute lung injury and pulmonary fibrosis attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair [PDF]

, 2015
© 2015 the American Physiological Society Fibroblast growth factors (Fgfs) mediate organ repair. Lung epithelial cell overexpression of Fgf10 postbleomycin injury is both protective and therapeutic, characterized by increased survival and attenuated ...
Henneke I., Quantius J., Königshoff M., Li X., Wilhelm J., Jones M., Rizvanov A., Hezel S., Herold S., Goth K., Bellusci S., Agha E., Seeger W., Günther A., Mackenzie B., Alam D., Chao C.   +16 more
core  

Hs3st3-Modified Heparan Sulfate Controls KIT+ Progenitor Expansion by Regulating 3-O-Sulfotransferases [PDF]

, 2014
SummaryThe exquisite control of growth factor function by heparan sulfate (HS) is dictated by tremendous structural heterogeneity of sulfated modifications.
Isabelle M.A. Lombaert, Cowherd, Samuel N, Matthew P. Hoffman, Patel, Vaishali N, Lombaert, Isabelle M A, Yongmei Xu, Jian Liu, Samuel N. Cowherd, Vaishali N. Patel, Xu, Yongmei, Liu, Jian, Nicholas W. Shworak, Shworak, Nicholas W, Hoffman, Matthew P, Cowherd, Samuel N., Hoffman, Matthew P., Patel, Vaishali N., Lombaert, Isabelle M.A., Shworak, Nicholas W.   +18 more
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Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer

Molecular Therapy: Nucleic Acids
Impaired fibroblast growth factor receptor (FGFR) signaling is associated with many human conditions, including growth disorders, degenerative diseases, and cancer.
Vladimira Zlinska, Zuzana Feketova, Aleksandra Czyrek, Julia Chudzian, Martina Lenarcic Zivkovic, Vlad-Constantin Ursachi, Pooja Dudeja, Bohumil Fafilek, Jan Rynes, Gustavo Rico-Llanos, Adolf Koudelka, Tanaya Roy, Martyna Biadun, Vendula Raskova, Katerina Svozilova, Michaela Stroblova, Mateusz Krzyscik, Kalina Hristova, Daniel Krowarsch, Silvie Foldynova-Trantirkova, Malgorzata Zakrzewska, Lukas Trantirek, Pavel Krejci   +22 more
doaj   +1 more source

A novel mouse Fgfr2 mutant, hobbyhorse (hob), exhibits complete XY gonadal sex reversal.

PLoS ONE, 2014
The secreted molecule fibroblast growth factor 9 (FGF9) plays a critical role in testis determination in the mouse. In embryonic gonadal somatic cells it is required for maintenance of SOX9 expression, a key determinant of Sertoli cell fate.
Pam Siggers, Gwenn-Aël Carré, Debora Bogani, Nick Warr, Sara Wells, Helen Hilton, Chris Esapa, Mohammad K Hajihosseini, Andy Greenfield   +8 more
doaj   +1 more source

In vitro Wnt signaling inhibition and fgfr2b expression.

, 2014
Representative examples of stage b2 lung explant culture, at D0∶0h (A, D, G, J) and D2∶48h (B, E, H, K) treated with DMSO (A, B), 20 µM (D, E), 30 µM (G, H) and 40 µM FH535 (J, K) and probed with fgfr2b (C, F, I, L); n = 4 for each stage.
Eduarda Carvalho-Correia (668144), Jorge Correia-Pinto (227737), Paulo daMota (668145), Rute Silva Moura (668143)   +3 more
core   +1 more source