Results 71 to 80 of about 2,012 (174)

Roll with the punches: Fibroblast growth factor 10 alleviates pyroptosis of alveolar epithelial cells in different immune niches

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Our study reveals a marked decrease of serum FGF10 levels in ARDS patients, correlating with P/F ratio, hospitalisation days and mortality rates. We clarify how FGF10 prevents AECs' pyroptosis triggered by different immune cell infiltrations in different ways.
Tianchang Wei, Xiaoyan Chen, Jian Xu, Weiqi Mao, Zhenlin Yang, Yuhan Wang, Yufan Li, Wenting Jin, Cuicui Chen, Cuiping Zhang, Yuanlin Song   +10 more
wiley   +1 more source

Characterization of the role of fibroblast growth factor 10 (Fgf10) and its receptor Fgfr2b on multipotent epithelial progenitor cells during early lung development [PDF]

, 2020
FGF10 signaling through FGFR2b is mandatory during early lung development as the deletion of either the ligand or the receptor leads to lung agenesis. In this dissertation, we report the role of FGF10/FGFR2b signaling on the early lung development (E12.5)
Dilai, Salma
core   +1 more source

Fgf22 regulated by Fgf3/Fgf8 signaling is required for zebrafish midbrain development

Biology Open, 2013
Summary Fibroblast growth factor (Fgf) signaling plays important roles in various developmental processes including brain development. Here, we identified zebrafish fgf22 predominantly expressed in the posterior midbrain and anterior midbrain–hindbrain ...
Ayumi Miyake, Nobuyuki Itoh
doaj   +1 more source

Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling

Developmental Biology, 2008
We previously demonstrated that Fibroblast Growth Factor 10 (FGF10) and its receptor FGFR2b play a key role in controlling the very early stages of mammary gland development during embryogenesis [Mailleux, A.A., Spencer-Dene, B., Dillon, C., Ndiaye, D., Savona-Baron, C., Itoh, N., Kato, S., Dickson, C., Thiery, J.P., and Bellusci, S. (2002).
Parsa, Sara, Ramasamy, Suresh K., De Langhe, Stijn, Gupte, Varsha V., Haigh, Jody J., Medina, Daniel, Bellusci, Savério   +6 more
openaire   +2 more sources

Development of the neurohypophysis: A major neuroendocrine interface

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract The neurohypophysis is a major central neuroendocrine interface regulating reproductive functions and water homeostasis. Distinct neurovascular cell types interact via evolutionarily conserved signaling molecules in the developing neurohypophysis, providing a model system for studying principles in neuroendocrine interface morphogenesis.
Athul R. Ramesh, Naveen Nedunchezhian, Md Hasan Ali, Sebastian Pęcherz, Natalia Kowalewska, Savani Anbalagan   +5 more
wiley   +1 more source

Role of FGF10/FGFR2b Signaling in Mouse Digestive Tract Development, Repair and Regeneration Following Injury

Frontiers in Cell and Developmental Biology, 2019
During embryonic development, the rudimentary digestive tract is initially a tube-like structure. It is composed of epithelial cells surrounded by mesenchymal cells.
Yu-Qing Lv, Yu-Qing Lv, Jin Wu, Xiao-Kun Li, Xiao-Kun Li, Jin-San Zhang, Jin-San Zhang, Saverio Bellusci, Saverio Bellusci, Saverio Bellusci   +9 more
doaj   +1 more source

Lineage Tracing of Distal Lung Epithelial Progenitors in Injury‐Induced Regeneration

The Clinical Respiratory Journal, Volume 19, Issue 12, December 2025.
Lineage tracing reveals the diverse stem‐like progenitors driving distal lung regeneration. We highlight how Clara cells, AT2 cells, bronchioalveolar stem cells, basal‐like progenitors, and other progenitors contribute to injury repair through context‐dependent plasticity.
Jian Xu, Yuhan Wang, Cuiping Zhang, Xiaoyan Chen, Tianchang Wei, Weiqi Mao, Yuanlin Song   +6 more
wiley   +1 more source

Signaling induced by FGFR2b-ligands interactionplays a critical function to control the amplification of the mesenchymal progenitors throughout limb development.

, 2013
(A) FGFR2b-ligands signaling plays a major function in the amplification of the mesenchymal cells that will give rise to the stylopod prior to limb bud induction.
Saverio Bellusci (1874743), Matthew Wheeler (475401), Xiaokun Li (166455), Sheryl Baptista (475400), Thomas Braun (269597), Guillermo Barreto (179056), Mohammad K. Hajihosseini (38987), Denise Al Alam (59722), Caterina Tiozzo (346568), Soula Danopoulos (346564), Gianni Carraro (38982), Sara Parsa (346562), Reza Tabatabai (475399)   +12 more
core   +1 more source

Lacrimal gland development and Fgf10-Fgfr2b signaling are controlled by 2-O- and 6-O-sulfated heparan sulfate

, 2011
Contains fulltext : 96048.pdf (Publisher’s version ) (Open Access)Heparan sulfate, an extensively sulfated glycosaminoglycan abundant on cell surface proteoglycans, regulates intercellular signaling through its binding to various growth
Esko, J.D., Tao, C., Andrea Powers, Kay Grobe, Xin Zhang, Roger Lawrence, Toin H. van Kuppevelt, Zhang, X., Xiuxia Qu, Wellington V. Cardoso, Grobe, K., Jeffrey D. Esko, Lawrence, R., Qu, X., Kuppevelt, A.H.M.S.M. van, Carbe, C., Cardoso, W.V., Christian Carbe, Chenqi Tao, Powers, A.   +19 more
core   +1 more source

A variant of fibroblast growth factor receptor 2 (Fgfr2) regulates left-right asymmetry in zebrafish.

PLoS ONE, 2011
Many organs in vertebrates are left-right asymmetrical located. For example, liver is at the right side and stomach is at the left side in human. Fibroblast growth factor (Fgf) signaling is important for left-right asymmetry.
Da-Wei Liu, Chia-Hao Hsu, Su-Mei Tsai, Chung-Der Hsiao, Wen-Pin Wang   +4 more
doaj   +1 more source