Results 61 to 70 of about 2,012 (174)
Orthodontics &Craniofacial Research, Volume 29, Issue 3, Page 538-545, June 2026.ABSTRACT Objective Mandibular retrognathism (MR) is a skeletal malocclusion in which patients have a deficient mandibular length, resulting in a more posterior position of the mandible. We aimed to investigate the association between Single nucleotide polymorphisms (SNPs) in Fibroblast Growth Factor Receptor 2 (FGFR2) gene and MR in germans.
Caio Luiz Bitencourt Reis +9 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.FGF10‐FGFR2 signaling is progressively impaired during liver fibrosis. FGF10 restoration protects hepatocytes from inflammatory and apoptotic injury. Hepatocyte FGFR2 mediates FGF10‐driven suppression of fibrogenic remodeling through the GSK3β/NF‐κB axis.
Xuanxin Yang +20 more
wiley +1 more source
Scientific Reports, 2021 Clostridium botulinum neurotoxin serotype A (BoNT/A) is a potent neurotoxin that serves as an effective therapeutic for several neuromuscular disorders via induction of temporary muscular paralysis.
Nicholas G. James +7 more
doaj +1 more source
"FGFR2b recombinant protein structural changes in interaction with Naringin" [PDF]
, 2016 Background: FGFR2b plays a significant role in cell signaling pathway, regulating several key biological processes including cellular differentiation and proliferation.
emad, tavakkoli
core
Stem cell mediated lung repair after influenza-induced injury: role of the Fgf10/Fgfr2b axis [PDF]
, 2015 Influenza virus pneumonia causes apoptosis of alveolar epithelial cells, disruption of the epithelial barrier and edema formation that affects gas exchange dramatically, resulting in the acute respiratory distress syndrome with poor outcome.
Quantius, Jennifer
core +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, Volume 600, Issue 2, Page 140-163, January 2026.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
The keratinocyte differentiation induced by FGFR2b requires sequential involvement of PKCa and PKCd
, 2018 The fibroblast growth factor receptors (FGFRs) are receptor tyrosine kinases expressed, by tissuespecific alternative splicing, in epithelial IIIb or mesenchymal IIIc isoforms and controlling key physiological processes, such as cell proliferation ...
Belleudi, F +4 more
core +1 more source
A deletion of
BMC Medical Genetics, 2011 Background Signalling by fibroblast growth factor receptor type 2 (FGFR2) normally involves a tissue-specific alternative splice choice between two exons (IIIb and IIIc), which generates two receptor isoforms (FGFR2b and FGFR2c respectively) with ...
Klatt Regan EM +3 more
doaj +1 more source
American Journal of Medical Genetics Part A, Volume 200, Issue 1, Page 215-222, January 2026.ABSTRACT Apert syndrome is a recognizable craniofacial condition characterized by craniosynostosis, hypertelorism, exorbitism, midface hypoplasia, and complex symmetrical bony and cutaneous ‘mitten’ syndactyly of all four limbs. Around 98% of affected patients have one of two heterozygous missense variants in the FGFR2 gene, encoding either p ...
Ramy Saad +8 more
wiley +1 more source
Sox10 Regulates Plasticity of Epithelial Progenitors toward Secretory Units of Exocrine Glands
Stem Cell Reports, 2019 Summary: Understanding how epithelial progenitors within exocrine glands establish specific cell lineages and form complex functional secretory units is vital for organ regeneration.
Harleen K. Athwal +8 more
doaj +1 more source