Results 161 to 170 of about 14,825 (199)

Safety of fibrates in cholestatic liver diseases

open access: yesLiver International, 2021
Off-label use of fibrates in patients with cholestatic liver diseases results in improved biochemical parameters and pruritus; however, their safety in this population has been a concern.
Cynthia Levy   +2 more
exaly   +2 more sources

Effects of Fibrates on Serum Metabolic Parameters

open access: yesCurrent Medical Research and Opinion, 2002
Fibric acid derivatives are a class of hypolipidaemic drugs used in the treatment of patients with hypertriglyceridaemia, mixed hyperlipidaemia and diabetic dyslipidaemia.
Moses Elisaf
exaly   +1 more source

Development of Fibrates as Important Scaffolds in Medicinal Chemistry

open access: yesChemMedChem, 2019
Fibrates are a class of phenoxyisobutyric acid derivatives mainly used as anti-hyperlipidemic agents. The fibrate scaffold has undergone a variety of chemical modifications, providing a wide spectrum of biological activities.
Barbara De Filippis   +2 more
exaly   +2 more sources

Effects of fibrates on C-reactive protein concentrations: a meta-analysis of randomized controlled trials

open access: yesClinical Chemistry and Laboratory Medicine, 2012
The effects of fibrates on C-reactive protein (CRP) are controversial. This meta-analysis was conducted to synthesize the available clinical trial evidence and summarize the effects of fibrates on CRP concentrations.
Dongfeng Gu, Xueli Yang, Yongchen Hao
exaly   +2 more sources

Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis

open access: yesLancet, The, 2010
Background Several clinical trials have reported inconsistent findings for the effect of fibrates on cardiovascular risk. We undertook a systematic review and meta-analysis to investigate the effects of fibrates on major clinical outcomes.
Bruce Neal, Alan Cass, Vlado Perkovic
exaly   +2 more sources

Statins, fibrates, and venous thromboembolism: a meta-analysis. [PDF]

open access: yesEuropean Heart Journal, 2010
Aims The aim is to make a systematic review of the literature to assess the effect of lipid-lowering drugs on venous thromboembolism (VTE) occurrence. Methods and results MEDLINE and EMBASE databases were searched to identify studies that evaluated the
Alessandro Squizzato   +2 more
exaly   +2 more sources

Fibrations and nullifications

Israel Journal of Mathematics, 2003
Preservation of homotopical structures by localization functors is a classical question in homotopy theory. In this paper the authors obtain necessary and sufficient conditions for a fibration sequence to be preserved by a nullification functor. Also, nullification functors \(L=P_W\) are characterized among localization functors \(L_f\) defined by ...
Berrick, A.J., Dror Farjoun, E.
openaire   +1 more source

Fibrates

2005
Atherosclerosis of the large arteries is the main origin of cerebro- and cardiovascular diseases, the leading causes of mortality and morbidity in industrialized countries. The pathophysiology of coronary and cerebrovascular atherosclerosis is multifactorial and complex. Fibrates are hypolipidemic drugs that lower progression of atherosclerotic lesions
R, Robillard   +4 more
openaire   +2 more sources

Approximating Approximate Fibrations by Fibrations

Canadian Journal of Mathematics, 1977
A map p: E → B between metric spaces has the approximate homotopy lifting property with respect to the space X if given a cover Ū of B and maps g: X → E and H: X × [0, 1] → B such that H(x, 0) = pg(x) for all x ϵ X, then there exists a map G: X × [0, 1] → E such that G(x, 0) = g(x) and pGt and Ht are Ū-close for all x ϵ X and t ϵ [0, 1]; i.e. given (x,
openaire   +1 more source

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