Results 41 to 50 of about 370,815 (388)
Biomolecules, 2021 This study aimed to analyze the effects of fibrin constructs enhanced with laminin-nidogen, implanted in the wounded rat soft palate. Fibrin constructs with and without laminin-nidogen were implanted in 1 mm excisional wounds in the soft palate of 9-week-
Doris H. Rosero Salazar +5 more
doaj +1 more source
Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and b1-integrin activation [PDF]
, 2018 Lymphatic invasion and lymph node metastasis correlate with poor clinical outcome in melanoma. However, the mechanisms of lymphatic dissemination in distant metastasis remain incompletely understood.
Alve, S +17 more
core +1 more source
Pharmaceutics, 2022 Recanalization of the occluded artery is the gold standard treatment for acute ischemic stroke, which includes enzymatic fibrinolytic treatment with the use of recombinant tissue plasminogen activators (rtPAs) to disrupt the occluding clot, the use of ...
María Luz Alonso-Alonso +9 more
doaj +1 more source
Proceedings of the National Academy of Sciences, 1979 High-symmetry models of the fibrin fiber are proposed that reproduce the experimentally observed high specific volume of the fiber. The models meet the following criteria: fibrin monomers have the three-domain Hall and Slayter structure; the monomers are arranged lengthwise into strands (protofibrils) in which successive monomers half overlap; the ...
openaire +3 more sources
Fibrin Gel Ultrastructure [PDF]
Biophysical Journal, 2010 Ischemic heart disease, which results from occlusion of one of the major coronary arteries as a consequence of thrombi and atherosclerotic plaque, continues to be the leading cause of morbidity and mortality in Western society, while stroke is the second leading cause of death worldwide.
Papi, Massimiliano +6 more
openaire +5 more sources
Nonlinear Elasticity in Biological Gels [PDF]
, 2004 Unlike most synthetic materials, biological materials often stiffen as they are deformed. This nonlinear elastic response, critical for the physiological function of some tissues, has been documented since at least the 19th century, but the molecular ...
AD Karakaplan +33 more
core +2 more sources
Research and Practice in Thrombosis and HaemostasisBackground: Embolization, or rupture of a thrombus, is a complication of thrombosis that increases mortality risk by up to 30%. Fibrin provides mechanical and structural stability to blood clots.
Ranjini K. Ramanujam +4 more
doaj +1 more source
Ex vivo engineering of blood and lymphatic microvascular networks
Vascular Biology, 2019 Despite tremendous efforts in preclinical research over the last decades, the clinical translation of therapeutic angiogenesis to grow stable and functional blood vessels in patients with ischemic diseases continues to prove challenging.
Jaana Schneider +2 more
doaj +1 more source
A xenograft study of human adipose stromal cell‐based vocal fold mucosal replacement in rabbits
Laryngoscope Investigative Otolaryngology, 2022 Objectives Vocal fold (VF) scarring, manifested by increased collagen, decreased glycosaminoglycans (GAGs), and disrupted elastic fibers, remains a negative consequence of VF injury or resection.
Eric K. Tran +6 more
doaj +1 more source
SPECT imaging of fibrin using fibrin‐binding peptides [PDF]
Contrast Media & Molecular Imaging, 2013 Noninvasive detection of fibrin in vivo using diagnostic imaging modalities may improve clinical decision‐making on possible therapeutic options in atherosclerosis, cancer and thrombus‐related pathologies such as pulmonary embolism and deep venous thrombosis.
Holger Grüll +7 more
openaire +3 more sources