Results 41 to 50 of about 374,474 (339)

Multi-scale strain-stiffening of semiflexible bundle networks [PDF]

, 2015
Bundles of polymer filaments are responsible for the rich and unique mechanical behaviors of many biomaterials, including cells and extracellular matrices.
Broedersz, C. P., Jansen, K. A., Koenderink, G. H., Kurniawan, N. A., MacKintosh, F. C., Piechocka, I. K.   +5 more
core   +2 more sources

Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile [PDF]

, 2016
Factor XIIIa (FXIIIa) is a transglutaminase that catalyzes the last step in the coagulation process. Orthostery is the only approach that has been exploited to design FXIIIa inhibitors.
Afosa, Daniel K., Al-Horani, Rami A., Desai, Umesh R., Karuturi, Rajesh, Lee, Michael   +4 more
core   +4 more sources

Intraoperative Thrombophilia-Associated Thrombosis of Both Saphenous Veins during Harvesting for Coronary Artery Bypass Grafting

TH Open, 2020
Introduction Intraoperative thrombosis of saphenous veins (SV) during open harvesting is very rare. Case Report We present a case of a 60-year-old male patient with multivessel coronary artery disease and a history of a non-ST elevation acute ...
Piotr Mazur, Michał Ząbczyk, Radosław Litwinowicz, Joanna Natorska, Bogusław Kapelak   +4 more
doaj   +1 more source

Physical forces regulating hemostasis and thrombosis: Vessels, cells, and molecules in illustrated review

Research and Practice in Thrombosis and Haemostasis, 2021
This illustrated review focuses on the physical forces that regulate hemostasis and thrombosis. These phenomena span from the vessel to the cellular to the molecular scales. Blood is a complex fluid with a viscosity that varies with how fast it flows and
Jessica Lin, Matthew G. Sorrells, Wilbur A. Lam, Keith B. Neeves   +3 more
doaj   +1 more source

Three states of stromal cells–solid, liquid, and aerosol–and innovative delivery methods not previously reported

Archives of Plastic Surgery, 2021
Clinical applications of stromal cells obtained mechanically from adipose tissue are quite popular methods. However, generally accepted protocols still do not exist.
Hasim Eray Copcu
doaj   +1 more source

Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. [PDF]

, 2009
PurposeDeposition of fibrin in the alveolar space is a hallmark of acute lung injury (ALI). Plasminogen activator inhibitor-1 (PAI-1) is an antifibrinolytic agent that is activated during inflammation. Increased plasma and pulmonary edema fluid levels of
Brady, Sandra, Curley, Martha AQ, Flori, Heidi, Matthay, Michael A, Sapru, Anil   +4 more
core   +2 more sources

A multiscale hybrid mathematical model of epidermal-dermal interactions during skin wound healing. [PDF]

, 2019
Following injury, skin activates a complex wound healing programme. While cellular and signalling mechanisms of wound repair have been extensively studied, the principles of epidermal-dermal interactions and their effects on wound healing outcomes are ...
Chen, Weitao, Du, Huijing, Figueroa, Seth, Guerrero-Juarez, Christian F, Nie, Qing, Plikus, Maksim V, Qiu, Yuchi, Wang, Yangyang   +7 more
core   +1 more source

Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses. [PDF]

, 2017
Distal extremity wounds are a significant clinical problem in horses and humans and may benefit from mesenchymal stem cell (MSC) therapy. This study evaluated the effects of direct wound treatment with allogeneic stem cells, in terms of gross, histologic,
Aristizobal, Fabio A, Bledsoe, Andrea, Bohannon-Worsley, Laurie K, Borjesson, Dori L, Clark, Kaitlin C, Davidyan, Arik, Gray, Sarah N, Kol, Amir, LeJeune, Sarah S, Textor, Jamie A, Walker, Naomi J, Woolard, Kevin D   +11 more
core   +1 more source

Histological analysis of short-term vital reactions in skin wounds: potential applications in forensic work

Brazilian Journal of Biology
In forensic medical work, in cases with homicide suspicion, it is important to be able to determine with the greatest possible precision when injuries occurred and whether during vital, or post-mortem conditions.
AR. Obac, EG. Carvalho, PCS. Silva, N. Fenerich-Verani, M. Almeida   +4 more
doaj   +1 more source

Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets [PDF]

, 2003
Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown.
Alex, Meike, Engelmann, Bernd, Klocke, Antje, Kotzsch, Matthias, Luther, Thomas, Morgenstern, Eberhard, Müller, Ingrid, Preissner, Klaus, Zahler, Stefan, Zieseniss, Susanne   +9 more
core   +1 more source