Results 71 to 80 of about 15,738 (247)

Heart‐On‐a‐Chip with Integrated Ultrasoft Mechanosensors for Continuous Measurement of Cell‐ and Tissue‐Scale Contractile Stresses

Small, EarlyView.
We present a heart‐on‐a‐chip platform embedded with ultrasoft mechanosensors for real‐time, multi‐scale stress mapping in engineered cardiac tissues. The system enables simultaneous quantification of local cell‐generated stresses and global tissue contractile forces.
Ali Mousavi, Christina‐Marie Boghdady, Shihao Cui, Sabra Rostami, Amid Shakeri, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Milica Radisic, Christopher Moraes, Houman Savoji   +10 more
wiley   +1 more source

Transforming acute exacerbations of chronic obstructive pulmonary disease (AECOPD) risk assessment: A multi‐algorithm machine learning approach for precise clinical phenotyping

VIEW, EarlyView.
We addressed the clinical need for individualized early identification of AECOPD by analyzing a longitudinal cohort of 878 COPD patients (20072024) and benchmarking 91 algorithms, yielding an interpretable ensemble model (AECOPD‐RS). The model showed strong performance (C‐index 0.815; validation 1/3/5‐year AUCs 0.864/0.865/0.855), with SHAP/VIMP ...
Yiqun Dong, Junyi Shen, Chaofan Fan, Anqi Lin, Peng Luo, Xin Chen   +5 more
wiley   +1 more source

Hyperprolactinemia during antipsychotics treatment increases the level of coagulation markers

Neuropsychiatric Disease and Treatment, 2015
Masamichi Ishioka, Norio Yasui-Furukori, Norio Sugawara, Hanako Furukori, Shuhei Kudo, Kazuhiko Nakamura Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, Japan Objective: The strong association between ...
Ishioka M, Yasui-Furukori N, Sugawara N, Furukori H, Kudo S, Nakamura K   +5 more
doaj  

Fibrin/fibrinogen Degradation Products Are Associated With Tumor Stage and Prognosis in Patients Undergoing Resection of Esophageal Cancer [PDF]

, 2021
Makoto Sakai, Makoto Sohda, Shintaro Uchida, Arisa Yamaguchi, Takayoshi Watanabe, Hideyuki Saito, Yasunari Ubukata, Nobuhiro Nakazawa, Kengo Kuriyama, Akihiko Sano, Hiroomi Ogawa, Takehiko Yokobori, Ken Shirabe, Hiroshi Saeki   +13 more
openalex   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Effectiveness, reliability, and validity of new Japanese diagnostic criteria for obstetrical disseminated intravascular coagulation

Scientific Reports
Since July 2022, obstetrical disseminated intravascular coagulation (DIC) in Japan has been diagnosed based on the new criteria (tentative version), which assesses the main underlying disease, fibrinogen level, and fibrin/fibrinogen degradation products ...
Mamoru Morikawa, Yoshiharu Takeda, Shigetaka Matsunaga, Shintaro Makino, Eriko Eto, Mariko Serizawa, Masafumi Nii, Jun Takeda, Hisashi Masuyama, Atsuo Itakura   +9 more
doaj   +1 more source

Common Hematologic Emergencies—Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias—A Pivotal Role of Clinical Laboratory

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Hematologic emergencies are urgent health conditions which result in significant mortality and morbidity unless timely therapeutic measures are taken. Therapeutic success depends on their timely and accurate recognition by hematology laboratory services.
Ganna Shestakova, Nicolas Ulrich Edgar, Anton V. Rets   +2 more
wiley   +1 more source

Modification by Drugs of Urinary Fibrin Fibrinogen Degradation Products in Glomerulonephritis [PDF]

, 1972
A. R. Clarkson, M. K. MacDonald, J. D. Cash, J. S. Robson   +3 more
openalex   +1 more source

A Retrospective Study of Adult and Pediatric D‐Dimer Tests to Identify Opportunities for Improved Utilization

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction D‐dimers are produced by lysis of cross‐linked fibrin. In children, D‐dimer testing is used to evaluate disseminated intravascular coagulation (DIC) and some inflammatory states, but its use is not validated for screening or ruling out suspected venous thromboembolic events (VTE).
Rabab Al Dawood, Hassan Abu Sabah, Natalie Mathews, James Douketis, Catherine Hayward   +4 more
wiley   +1 more source

Construction of a prognostic assessment model for diabetic nephropathy based on serum fibrinogen and renal tissue IFTA score

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Objective To explore the association between serum fibrinogen (FIB) and clinicopathological features and renal prognosis in type 2 diabetic nephropathy (T2DN), and develop a web‐based dynamic model to predict renal progression. Methods This paper retrospectively enrolled 173 biopsy‐proven T2DN patients and stratified them by the optimal FIB ...
Lin Ning, Xiaohong Zhang, Yuan Fang, Mengjie Weng, Yongjie Zhuo, Jianxin Wan   +5 more
wiley   +1 more source