Results 1 to 10 of about 274,907 (333)
Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects
Biomedicines, 2022 Fibrinogen (Fg) and its derivatives play a considerable role in many diseases. For example, increased levels of Fg have been found in many inflammatory diseases, such as Alzheimer’s disease, multiple sclerosis, traumatic brain injury, rheumatoid ...
Nurul H. Sulimai +2 more
doaj +3 more sources
Fibrinogen heterogeneity in horses
Journal of Veterinary Internal Medicine, 2021 Background Fibrinogen heterogeneity has been observed in humans and can influence fibrinogen measurements when using the modified Clauss assay. We hypothesized that fibrinogen heterogeneity also exists in horses.
Elise B. Russell +3 more
doaj +1 more source
Orphan nuclear receptor ERRγ is a key regulator of human fibrinogen gene expression. [PDF]
PLoS ONE, 2017 Fibrinogen, 1 of 13 coagulation factors responsible for normal blood clotting, is synthesized by hepatocytes. Detailed roles of the orphan nuclear receptors regulating fibrinogen gene expression have not yet been fully elucidated.
Yaochen Zhang +15 more
doaj +1 more source
Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations. [PDF]
PLoS ONE, 2017 Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression.
H Toinét Cronjé +5 more
doaj +1 more source
Journal of Cardiothoracic Surgery, 2023 Objective This study aims to examine the impact of preoperative fibrinogen concentration on the short-term outcomes and hospital length of stay (LOS) of patients undergoing Coronary Artery Bypass Grafting (CABG).
Chunsheng Huang +5 more
doaj +1 more source
Fibrinogen and Bleeding in Adult Cardiac Surgery: A Review of the Literature
Surgeries, 2021 Background: Fibrinogen is a substrate for blood clots formation. In cardiac surgery, a number of different mechanisms lead to a decrease in fibrinogen levels and consequent impaired haemostasis.
Višnja Ikić
doaj +1 more source
Cells, 2020 Immune complexes containing citrullinated fibrinogen are present in the sera and synovium of rheumatoid arthritis patients and potentially contribute to synovitis. However, fibrinogen can inhibit the osteoclastogenesis of precursor cells. We investigated
Ji Soo Kim +7 more
doaj +1 more source
Frontiers in Pediatrics, 2021 Fibrinogen is a key coagulation protein, playing a critical role in hemostasis. It is the first factor to decrease to critical levels during bleeding. Hypofibrinogenemia is an important risk factor for bleeding in clinical settings, including pediatric ...
Elise J. Huisman +3 more
doaj +1 more source
Prognostic Impact of Pretreatment Plasma Fibrinogen in Patients with Locally Advanced Oral and Oropharyngeal Cancer. [PDF]
PLoS ONE, 2016 We aimed to determine the prognostic significance of pretreatment plasma fibrinigen in patients with oral and oropharyngeal squamous cell carcinoma (OOSCC).A cohort of 183 patients with locally advanced OOSCC receiving preoperative chemoradiotherapy was ...
Daniel Holzinger +10 more
doaj +1 more source
Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk
Haematologica, 2020 Complement C3 binds fibrinogen and compromises fibrin clot lysis thereby enhancing thrombosis risk. We investigated the role of fibrinogen-C3 interaction as a novel therapeutic target to reduce thrombosis risk by analysing: i) consistency in the ...
Rhodri J. King +12 more
doaj +1 more source