Results 1 to 10 of about 352,535 (382)

Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial

Critical Care, 2018
Background There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial, we explored the use of fibrinogen
Nicola Curry, Claire Foley, Henna Wong, Ana Mora, Elinor Curnow, Agne Zarankaite, Renate Hodge, Valerie Hopkins, Alison Deary, James Ray, Phil Moss, Matthew J. Reed, Suzanne Kellett, Ross Davenport, Simon Stanworth   +14 more
doaj   +2 more sources

Fibrinogen-related proteins in ixodid ticks

Parasites & Vectors, 2011
Background Fibrinogen-related proteins with lectin activity are believed to be part of the tick innate immune system. Several fibrinogen-related proteins have been described and characterised mainly on the basis of their cDNA sequences while direct ...
Vancova Marie, Fiser Miroslav, Dupejova Jarmila, Sterba Jan, Grubhoffer Libor   +4 more
doaj   +1 more source

Adsorption of proteins to thin-films of PDMS and its effect on the adhesion of human endothelial cells [PDF]

, 2011
This paper describes a simple and inexpensive procedure to produce thin-films of poly(dimethylsiloxane). Such films were characterized by a variety of techniques (ellipsometry, nuclear magnetic resonance, atomic force microscopy, and goniometry) and ...
Bizios, Rena, Castro Guerrero, Carlos, Chumbimuni Torres, Karin Y., Coronado, Ramon E., Garcia, Carlos D., Mfuh, Adelphe M., Negrete, George R., Silva, María Fernanda   +7 more
core   +2 more sources

Fibrinogen induces inflammatory responses via the immune activating receptor LILRA2

Frontiers in Immunology
The leukocyte immunoglobulin-like receptor (LILR) family, a group of primate-specific immunoreceptors, is widely expressed on most immune cells and regulates immune responses through interactions with various ligands. The inhibitory type, LILRB, has been
Yifan Li, Yifan Li, Kouyuki Hirayasu, Kouyuki Hirayasu, Gen Hasegawa, Gen Hasegawa, Yosei Tomita, Yosei Tomita, Yuko Hashikawa, Yuko Hashikawa, Yuko Hashikawa, Ryosuke Hiwa, Hisashi Arase, Hisashi Arase, Hisashi Arase, Hisashi Arase, Rikinari Hanayama, Rikinari Hanayama   +17 more
doaj   +1 more source

D-Dimer Combined with Fibrinogen Predicts the Risk of Venous Thrombosis in Fracture Patients

Emergency Medicine International, 2020
Objective. While D-dimer can successfully diagnose venous thrombosis due to its excellent negative predictive value (NPV), it cannot be used to detect venous thromboembolism (VTE) because of its low positive predictive value (PPV).
Chaohui Lin, Yifan Chen, Bin Chen, Ke Zheng, Xiongbiao Luo, Fengfei Lin   +5 more
doaj   +1 more source

Circulating markers of arterial thrombosis and late-stage age-related macular degeneration: a case-control study.

, 2010
PURPOSE: The aim of this study was to examine the relation of late-stage age-related macular degeneration (AMD) with markers of systemic atherothrombosis. METHODS: A hospital-based case-control study of AMD was undertaken in London, UK.
A R Rudnicka, A Shankar, A von Clauss, AC Bird, AR Rudnicka, B Dasch, BG Armstrong, BL De Stavola, C Bunce, C Delcourt, CG Owen, DA Schaumberg, DA Schaumberg, DS Friedman, E Sato, Fibrinogen Studies Collaboration, G Chaine, G Malukiewicz-Wisniewska, GD Lowe, GJ Miller, H Hirvela, J Thornton, JA Cooper, JA Mares-Perlman, JJ Wang, JM Seddon, JM Seddon, JR Evans, JR Evans, JR Vingerling, KH Wu, L Hyman, N Cheung, N Congdon, P K MacCallum, PH Whincup, PK MacCallum, PL Lip, PT de Jong, R Klein, R Klein, R Klein, R Klein, R Klein, R Klein, R Klein, R Klein, R Klein, R Whitelocke, RD Sperduto, T Anderssen, T W Meade, The eye disease case-control study group, TW Meade, TY Wong, W Smith, W Smith, WG Christen, Y Duan, Y Tao   +59 more
core   +1 more source

Comparative study of osteogenic activity of multilayers made of synthetic and biogenic polyelectrolytes [PDF]

, 2017
Polyelectrolyte multilayer (PEM) coatings on biomaterials are applied to tailor adhesion, growth, and function of cells on biomedical implants. Here, biogenic and synthetic polyelectrolytes (PEL) are used for layer-by-layer assembly to study the ...
Gonzalez-Garcia, Cristina, Groth, Thomas, Guduru, Deepak, Niepel, Marcus S., Salmeron-Sanchez, Manuel   +4 more
core   +1 more source

Neonatal Fc receptor is involved in the protection of fibrinogen after its intake in peripheral blood mononuclear cells

Journal of Translational Medicine, 2018
Background Fibrinogen is a central player in the blood coagulation cascade and one of the most abundant plasma proteins. This glycoprotein also triggers important events (e.g., cell spreading, the respiratory burst and degranulation) in neutrophil cells ...
Tiziana Alberio, Greta Forlani, Marta Lualdi, Giovanna Tosi, Roberto S. Accolla, Mauro Fasano   +5 more
doaj   +1 more source

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis [PDF]

, 2009
Platelets play a fundamental role in hemostasis and thrombosis. They are also involved in pathologic conditions resulting from blocked blood vessels, including myocardial infarction and ischemic stroke.
Abtahian, Alexandra Mazharian, Arias-Salgado, Arias-Salgado, Arthur Weiss, Asselin, Auger, Avecilla, Baker, Best, Best, Cheli, Choudhuri, Dhanjal, Dorahy, Dubois, Ezumi, Gibbins, Gibbins, Harper, Hermiston, Holsinger, Jenson Lim, Jing W. Zhu, Jocelyn M. Auger, Kalia, Kato, Klages, Kovalenko, Kralisz, Kristin N. Kornerup, Le Pera, Lin, Lin, Liu, Mangin, McCarty, McNeill, Michael G. Tomlinson, Minuz, Moarefi, Mocsai, Morton, Neena Kalia, Nonne, Obergfell, Palka, Park, Pasquet, Pasquet, Pasquet, Pearce, Poole, Quek, Senis, Snell, Somani, Sorby, Steve G. Thomas, Steve P. Watson, Stuart Ellison, Superti-Furga, Suzuki-Inoue, Suzuki-Inoue, Tarvinder Dhanjal, Tsuboi, Vandendries, Wagner, Watanabe, Watson, Wonerow, Woodside, Xu, Xu, Yamaguchi, Yan Zhao, Yotis A. Senis, Young, Zhang, Zhu   +79 more
core   +2 more sources

A role for Syk-kinase in the control of the binding cycle of the β2 integrins (CD11/CD18) in human polymorphonuclear neutrophils [PDF]

, 2003
A fine control of β2 integrin (CD11/CD18)-mediated firm adhesion of human neutrophils to the endothelial cell monolayer is required to allow ordered emigration.
Arnaout, Arnaout, Bilsland, Bohnsack, Clark, Coxon, Danilenko, Diamond, Diamond, Dustin, El-Hillal, Fougerolles, Geahlen, Harder, Hjorth, Hynes, Kooyk, Kooyk, Krauss, Laemmli, Law, Lawson, Loike, Lu, Lub, Mocsai, Mocsai, Nathan, Ojaniemi, Olivier, Ota, Robinson, Simons, Smilenov, Springer, Tanaka, Vines, Walzog, Walzog, Walzog, Walzog, Willeke, Woodside, Wright, Wright, Yan, Yan, Zhang   +47 more
core   +1 more source