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Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects
Biomedicines, 2022 Fibrinogen (Fg) and its derivatives play a considerable role in many diseases. For example, increased levels of Fg have been found in many inflammatory diseases, such as Alzheimer’s disease, multiple sclerosis, traumatic brain injury, rheumatoid ...
Nurul H. Sulimai +2 more
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“No End Point Detected”: A Unique Coagulation Profile Unmasking Dysfibrinogenemia [PDF]
Case Reports in HematologyDysfibrinogenemia is a rare qualitative fibrinogen disorder that can present with bleeding, thrombosis, or both. We report a case of a young woman with first-trimester pregnancy loss and severe hemorrhage, whose coagulation tests reported “no end point ...
Kelsey Uminski, Xiu Yan Jiang
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Relationship between plasma sialic acid and fibinogen concentration and incident micro-and macrovascular complications in type 1 diabetes [PDF]
, 2008 AIMS/HYPOTHESIS: Type 1 diabetes is associated with an increased risk of vascular complications. This increased risk could be explained by sialic acid and/or fibrinogen.
CHATURVEDI N +5 more
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Journal of Cardiothoracic Surgery, 2023 Objective This study aims to examine the impact of preoperative fibrinogen concentration on the short-term outcomes and hospital length of stay (LOS) of patients undergoing Coronary Artery Bypass Grafting (CABG).
Chunsheng Huang +5 more
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Fibrinogen heterogeneity in horses
Journal of Veterinary Internal Medicine, 2021 Background Fibrinogen heterogeneity has been observed in humans and can influence fibrinogen measurements when using the modified Clauss assay. We hypothesized that fibrinogen heterogeneity also exists in horses.
Elise B. Russell +3 more
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Orphan nuclear receptor ERRγ is a key regulator of human fibrinogen gene expression. [PDF]
PLoS ONE, 2017 Fibrinogen, 1 of 13 coagulation factors responsible for normal blood clotting, is synthesized by hepatocytes. Detailed roles of the orphan nuclear receptors regulating fibrinogen gene expression have not yet been fully elucidated.
Yaochen Zhang +15 more
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Cells, 2020 Immune complexes containing citrullinated fibrinogen are present in the sera and synovium of rheumatoid arthritis patients and potentially contribute to synovitis. However, fibrinogen can inhibit the osteoclastogenesis of precursor cells. We investigated
Ji Soo Kim +7 more
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Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations. [PDF]
PLoS ONE, 2017 Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression.
H Toinét Cronjé +5 more
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Fibrinogen and Bleeding in Adult Cardiac Surgery: A Review of the Literature
Surgeries, 2021 Background: Fibrinogen is a substrate for blood clots formation. In cardiac surgery, a number of different mechanisms lead to a decrease in fibrinogen levels and consequent impaired haemostasis.
Višnja Ikić
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Frontiers in Pediatrics, 2021 Fibrinogen is a key coagulation protein, playing a critical role in hemostasis. It is the first factor to decrease to critical levels during bleeding. Hypofibrinogenemia is an important risk factor for bleeding in clinical settings, including pediatric ...
Elise J. Huisman +3 more
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