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Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial
Trials, 2017 Background Haemorrhage is a leading cause of death in severe trauma. Fibrinogen plays a critical role in maintaining haemostasis in traumatic haemorrhage. Early fibrinogen replacement is recommended by several international trauma guidelines using either
James Winearls +15 more
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Journal of Immunology Research, 2018 Background. Inflammation is an important hallmark of cancer. Fibrinogen and albumin are both vital factors in systemic inflammation. This study investigated the prognostic value of the fibrinogen/albumin ratio in HCC patients who underwent curative ...
Qiaodong Xu +13 more
doaj +2 more sources
Critical Care, 2018 Background There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial, we explored the use of fibrinogen
Nicola Curry +14 more
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Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects
Biomedicines, 2022 Fibrinogen (Fg) and its derivatives play a considerable role in many diseases. For example, increased levels of Fg have been found in many inflammatory diseases, such as Alzheimer’s disease, multiple sclerosis, traumatic brain injury, rheumatoid ...
Nurul H. Sulimai +2 more
doaj +1 more source
Relationship between plasma sialic acid and fibinogen concentration and incident micro-and macrovascular complications in type 1 diabetes [PDF]
, 2008 AIMS/HYPOTHESIS: Type 1 diabetes is associated with an increased risk of vascular complications. This increased risk could be explained by sialic acid and/or fibrinogen.
CHATURVEDI N +5 more
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Fibrinogen and Atherosclerotic Cardiovascular Diseases—Review of the Literature and Clinical Studies
International Journal of Molecular Sciences, 2021 Atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease, cerebrovascular disease, and peripheral arterial disease, represent a significant cause of premature death worldwide.
Stanisław Surma, M. Banach
semanticscholar +1 more source
Journal of Cardiothoracic Surgery, 2023 Objective This study aims to examine the impact of preoperative fibrinogen concentration on the short-term outcomes and hospital length of stay (LOS) of patients undergoing Coronary Artery Bypass Grafting (CABG).
Chunsheng Huang +5 more
doaj +1 more source
The International Journal of Biochemistry & Cell Biology, 1999 Fibrinogen is a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. As well as controlling blood loss at sites of tissue damage, other properties of fibrinogen have recently been discovered ...
Herrick, SE +3 more
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Fibrinogen heterogeneity in horses
Journal of Veterinary Internal Medicine, 2021 Background Fibrinogen heterogeneity has been observed in humans and can influence fibrinogen measurements when using the modified Clauss assay. We hypothesized that fibrinogen heterogeneity also exists in horses.
Elise B. Russell +3 more
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Journal of Clinical Pathology, 1965 Platelet fibrinogen has been studied in normal, thrombasthenic, and hypofibrinogenaemic subjects. It has been differentiated into adsorbed (plasma) and extractable (intraplatelet) fractions. Isotopic studies suggest that exchange does not occur between intraplatelet and plasma fibrinogen and it appears possible that the intra-platelet fraction may be ...
P A, Castaldi, J, Caen
openaire +2 more sources