Results 1 to 10 of about 112,237 (160)

A Novel Inflammation-Based Prognostic Score: The Fibrinogen/Albumin Ratio Predicts Prognoses of Patients after Curative Resection for Hepatocellular Carcinoma

Journal of Immunology Research, 2018
Background. Inflammation is an important hallmark of cancer. Fibrinogen and albumin are both vital factors in systemic inflammation. This study investigated the prognostic value of the fibrinogen/albumin ratio in HCC patients who underwent curative ...
Qiaodong Xu, Yongcong Yan, Songgang Gu, Kai Mao, Jianlong Zhang, Pinbo Huang, Zhenyu Zhou, Zheng Chen, Shaodong Zheng, Jiahong Liang, Zhihua Lin, Jie Wang, Jiang Yan, Zhiyu Xiao   +13 more
doaj   +2 more sources

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

Nature Communications, 2015
Autoimmunity and macrophage recruitment into the central nervous system (CNS) are critical determinants of neuroinflammatory diseases. However, the mechanisms that drive immunological responses targeted to the CNS remain largely unknown.
Jae Kyu Ryu, Justin P Chan, Hans Lassmann   +2 more
exaly   +2 more sources

Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial

Critical Care, 2018
Background There is increasing interest in the timely administration of concentrated sources of fibrinogen to patients with major traumatic bleeding. Following evaluation of early cryoprecipitate in the CRYOSTAT 1 trial, we explored the use of fibrinogen
Nicola Curry, Claire Foley, Henna Wong, Ana Mora, Elinor Curnow, Agne Zarankaite, Renate Hodge, Valerie Hopkins, Alison Deary, James Ray, Phil Moss, Matthew J. Reed, Suzanne Kellett, Ross Davenport, Simon Stanworth   +14 more
doaj   +2 more sources

Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial

Trials, 2017
Background Haemorrhage is a leading cause of death in severe trauma. Fibrinogen plays a critical role in maintaining haemostasis in traumatic haemorrhage. Early fibrinogen replacement is recommended by several international trauma guidelines using either
James Winearls, Martin Wullschleger, Elizabeth Wake, Catherine Hurn, Jeremy Furyk, Glenn Ryan, Melita Trout, James Walsham, Anthony Holley, Jeremy Cohen, Megan Shuttleworth, Wayne Dyer, Gerben Keijzers, John F Fraser, Jeffrey Presneill, Don Campbell   +15 more
doaj   +2 more sources

Fibrinogen-like Protein 1 Is a Major Immune Inhibitory Ligand of LAG-3

Cell, 2019
Jun Wang, Miguel F F Sanmamed, Weiwei Yin   +2 more
exaly   +2 more sources

Fibrinogen and fibrin structure and functions

Journal of Thrombosis and Haemostasis, 2005
M. Mosesson
exaly   +2 more sources

Fibrinogen and Fibrin in Hemostasis and Thrombosis

Arteriosclerosis, Thrombosis, and Vascular Biology, 2017
Sravya Kattula, James R Byrnes, Alisa S Wolberg   +2 more
exaly   +2 more sources

Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects

Biomedicines, 2022
Fibrinogen (Fg) and its derivatives play a considerable role in many diseases. For example, increased levels of Fg have been found in many inflammatory diseases, such as Alzheimer’s disease, multiple sclerosis, traumatic brain injury, rheumatoid ...
Nurul H. Sulimai, Jason Brown, David Lominadze   +2 more
doaj   +1 more source

Fibrinogen and Atherosclerotic Cardiovascular Diseases—Review of the Literature and Clinical Studies

International Journal of Molecular Sciences, 2021
Atherosclerotic cardiovascular diseases (ASCVD), including coronary artery disease, cerebrovascular disease, and peripheral arterial disease, represent a significant cause of premature death worldwide.
Stanisław Surma, M. Banach
semanticscholar   +1 more source

Elevated Plasma Fibrinogen Is Associated With Excessive Inflammation and Disease Severity in COVID-19 Patients

Frontiers in Cellular and Infection Microbiology, 2021
Background The coronavirus disease-19 (COVID-19) is characterized with intense inflammatory response, cardiac involvement, and coagulopathy. Fibrinogen, as a biomarker for inflammation, cardiovascular disease, and coagulation, has not been fully ...
Jingrui Sui, D. Noubouossie, S. Gandotra, Liyun Cao   +3 more
semanticscholar   +1 more source