Results 1 to 10 of about 160,141 (116)
The Conversion of Fibrinogen to Fibrin: Recombinant Fibrinogen Typifies Plasma Fibrinogen [PDF]
Blood, 1997 AbstractPlasma fibrinogen is a mixture of multiple molecular forms arising mainly through alternative mRNA processing and subsequent posttranslational modification. Recombinant fibrinogen is synthesized without alternative mRNA processing in a cultured cell system that may generate novel posttranslational modifications.
O V, Gorkun +3 more
openaire +2 more sources
Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects
Biomedicines, 2022 Fibrinogen (Fg) and its derivatives play a considerable role in many diseases. For example, increased levels of Fg have been found in many inflammatory diseases, such as Alzheimer’s disease, multiple sclerosis, traumatic brain injury, rheumatoid arthritis, systemic lupus erythematosus, and cancer.
Nurul H. Sulimai +2 more
openaire +3 more sources
Journal of Clinical Pathology, 1965 Platelet fibrinogen has been studied in normal, thrombasthenic, and hypofibrinogenaemic subjects. It has been differentiated into adsorbed (plasma) and extractable (intraplatelet) fractions. Isotopic studies suggest that exchange does not occur between intraplatelet and plasma fibrinogen and it appears possible that the intra-platelet fraction may be ...
P A, Castaldi, J, Caen
openaire +2 more sources
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2004 Fibrinogen is the major plasma protein coagulation factor. Low plasma fibrinogen concentrations are therefore associated with an increased risk of bleeding due to impaired primary and secondary haemostasis. Fibrinogen is a classical positive acute-phase reactant protein and is an independent predictor of coronary heart disease events.
Gordon D O, Lowe +2 more
openaire +2 more sources
Clinical Chemistry, 1967 Abstract Precise, reproducible quantitation of fibrinogen from plasma using thrombin to convert it to fibrin requires careful attention to the technics of clot formation and syneresis. The precision of the method outlined indicates a coefficient of variation of 1.2% with replicate samples.
W R, Swaim, M B, Feders
openaire +2 more sources
Fibrinogen replacement therapy for congenital fibrinogen deficiency [PDF]
Journal of Thrombosis and Haemostasis, 2011 This review of published studies was conducted to derive data on patients with congenital fibrinogen deficiency (CFD), including dosing of fibrinogen replacement therapy, outcome, and adverse events, either temporally related or distant to fibrinogen replacement, in order to assist clinicians in developing treatment plans for patients with CFD.
L, Bornikova +4 more
openaire +2 more sources
Frontiers in OncologyElevated plasma fibrinogen (Fg) levels consistently correlate with an unfavorable prognosis in various tumor patient cohorts. Within the tumor microenvironment, aberrant deposition and expression of Fg have been consistently observed, interacting with multiple cellular receptors and thereby accentuating its role as a regulator of inflammatory processes.
Xinyuan Wu +7 more
openaire +3 more sources
Estimation of Fibrinogen [PDF]
Journal of Clinical Pathology, 1972 R, Henderson, A S, Todd
openaire +2 more sources
Collegium antropologicum, 2005 This paper reviews the advances in understanding of fibrinogen structure and function, its genetic and environmental determinants, role in the process of hemostasis, platelet aggregation, plasma viscosity and erythrocyte aggregation, cellular and matrix interactions, inflammation, wound healing, tumor development, atherogenesis and involvement in ...
Pulanić, Dražen, Rudan, Igor
openaire +3 more sources
Dysfibrinogenemia in Pregnancy: A Case Series Highlighting Diagnostic Challenges and Multidisciplinary Management. [PDF]
CureusMahurkar S +3 more
europepmc +1 more source