Results 21 to 30 of about 299,922 (347)

Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations. [PDF]

PLoS ONE, 2017
Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression.
H Toinét Cronjé, Cornelie Nienaber-Rousseau, Lizelle Zandberg, Zelda de Lange, Fiona R Green, Marlien Pieters   +5 more
doaj   +1 more source

Fibrinogen and Bleeding in Adult Cardiac Surgery: A Review of the Literature

Surgeries, 2021
Background: Fibrinogen is a substrate for blood clots formation. In cardiac surgery, a number of different mechanisms lead to a decrease in fibrinogen levels and consequent impaired haemostasis.
Višnja Ikić
doaj   +1 more source

Pediatric Fibrinogen PART I—Pitfalls in Fibrinogen Evaluation and Use of Fibrinogen Replacement Products in Children

Frontiers in Pediatrics, 2021
Fibrinogen is a key coagulation protein, playing a critical role in hemostasis. It is the first factor to decrease to critical levels during bleeding. Hypofibrinogenemia is an important risk factor for bleeding in clinical settings, including pediatric ...
Elise J. Huisman, Elise J. Huisman, Elise J. Huisman, Gemma Louise Crighton   +3 more
doaj   +1 more source

Fibrinogen metabolic responses to trauma

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2009
Coagulation complications are significant contributors to morbidity and mortality in trauma patients. Although the lethal triad of hypothermia, acidosis and coagulopathy has been recognized for over a decade, the underlying mechanisms related to the ...
Martini Wenjun
doaj   +1 more source

Guidelines on fibrinogen assays [PDF]

, 2003
No abstract ...
Becker, Blanco, Blomback, Cambas, Chantarangkul, Chantarangkul, Chitolie, Chitolie, Clauss, Cremer, Cushman, De Cristofaro, De Maat, De Metz, Eliasson, Gaffney, Gordon D. O. Lowe, Hantgan, Haverkate, Hoffmann, Humphries, Ian J. Mackie, Jacobsson, Kitchen, Kluft, Lawrie, Lowe, Lowe, Ludlam, Machin, Mackie, Marder, MDA, MDA, Natelson, NCCLS, Nieuwenhuizen, Oosting, Palareti, Rampling, Ratnoff, Rosenson, Rossi, Samuel J. Machin, Steven Kitchen, Swain, Sweetnam, Sweetnam, Thompson, Van Der Bom, Vermylen, Whicher, World Health Organisation Report   +52 more
core   +1 more source

Association of Factor V Secretion with Protein Kinase B Signaling in Platelets from Horses with Atypical Equine Thrombasthenia. [PDF]

, 2015
BackgroundTwo congenital bleeding diatheses have been identified in Thoroughbred horses: Glanzmann thrombasthenia (GT) and a second, novel diathesis associated with abnormal platelet function in response to collagen and thrombin stimulation.Hypothesis ...
Blevins, G, Norris, JW, Pombo, M, Shirley, E, Tablin, F   +4 more
core   +1 more source

Migraine and vascular disease biomarkers: A population-based case-control study. [PDF]

, 2018
Background The underpinnings of the migraine-stroke association remain uncertain, but endothelial activation is a potential mechanism. We evaluated the association of migraine and vascular disease biomarkers in a community-based population.
Ferrari, Michel D., Herial, Nabeel, Khubchandani, Jagdish, Koppen, Hille, Kruit, Mark C., Launer, Lenore J., Palm-Meinders, Inge H., Terwindt, Gisela M., Tietjen, Gretchen E., van Buchem, Mark A.   +9 more
core   +2 more sources

Risk Factors for Postoperative Fibrinogen Deficiency after Surgical Removal of Intracranial Tumors.

PLoS ONE, 2015
Higher levels of fibrinogen, a critical element in hemostasis, are associated with increased postoperative survival rates, especially for patients with massive operative blood loss.
Naili Wei, Yanfei Jia, Xiu Wang, Yinian Zhang, Guoqiang Yuan, Baotian Zhao, Yao Wang, Kai Zhang, Xinding Zhang, Yawen Pan, Jianguo Zhang   +10 more
doaj   +1 more source

InforMing the PAthway of COPD Treatment (IMPACT) trial: fibrinogen levels predict risk of moderate or severe exacerbations

Respiratory Research, 2021
Background Fibrinogen is the first qualified prognostic/predictive biomarker for exacerbations in patients with chronic obstructive pulmonary disease (COPD).
Dave Singh, Gerard J. Criner, Mark T. Dransfield, David M. G. Halpin, MeiLan K. Han, Peter Lange, Sally Lettis, David A. Lipson, David Mannino, Neil Martin, Fernando J. Martinez, Bruce E. Miller, Robert Wise, Chang-Qing Zhu, David Lomas   +14 more
doaj   +1 more source

Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study [PDF]

, 2000
The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an ...
Ann Rumley, Christopher Packard, Gordon Lowe, Ian Ford, James Shepherd, John Norrie, null null, Peter Macfarlane, Stuart Cobbe   +8 more
core   +1 more source